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Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis.
Nikolic I, Ruiz-Garrido I, Crespo M, Romero-Becerra R, Leiva-Vega L, Mora A, León M, Rodríguez E, Leiva M, Plata-Gómez AB, Alvarez Flores MB, Torres JL, Hernández-Cosido L, López JA, Vázquez J, Efeyan A, Martin P, Marcos M, Sabio G. Nikolic I, et al. Among authors: leon m. EMBO Rep. 2024 Jun;25(6):2635-2661. doi: 10.1038/s44319-024-00149-y. Epub 2024 May 10. EMBO Rep. 2024. PMID: 38730210 Free PMC article.
MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation.
Romero-Becerra R, Mora A, Manieri E, Nikolic I, Santamans AM, Montalvo-Romeral V, Cruz FM, Rodríguez E, León M, Leiva-Vega L, Sanz L, Bondía V, Filgueiras-Rama D, Jiménez-Borreguero LJ, Jalife J, Gonzalez-Teran B, Sabio G. Romero-Becerra R, et al. Among authors: leon m. Elife. 2022 Aug 16;11:e75250. doi: 10.7554/eLife.75250. Elife. 2022. PMID: 35971771 Free PMC article.
p38γ is essential for cell cycle progression and liver tumorigenesis.
Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G. Tomás-Loba A, et al. Among authors: leon m. Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10. Nature. 2019. PMID: 30971822
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension.
Santamans AM, Cicuéndez B, Mora A, Villalba-Orero M, Rajlic S, Crespo M, Vo P, Jerome M, Macías Á, López JA, Leiva M, Rocha SF, León M, Rodríguez E, Leiva L, Pintor Chocano A, García Lunar I, García-Álvarez A, Hernansanz-Agustín P, Peinado VI, Barberá JA, Ibañez B, Vázquez J, Spinelli JB, Daiber A, Oliver E, Sabio G. Santamans AM, et al. Among authors: leon m. Sci Adv. 2024 Jan 19;10(3):eadk6524. doi: 10.1126/sciadv.adk6524. Epub 2024 Jan 19. Sci Adv. 2024. PMID: 38241373 Free PMC article.
Clinical outcomes with thin versus thick strut polymer-free biolimus-coated stents at 3 years.
Eberli FR, Oldroyd KG, Urban P, Krucoff MW, Morice MC, Tanguay JF, Leon MB, Brunel P, Maillard L, Lipiecki J, Cook S, Berland J, Hovasse T, Carrié D, Schütte D, Sadozai Slama S, Garot P. Eberli FR, et al. Among authors: leon mb. Open Heart. 2024 Jun 18;11(1):e002679. doi: 10.1136/openhrt-2024-002679. Open Heart. 2024. PMID: 38890129 Free article.
Deep Learning for Echo Analysis, Tracking, and Evaluation of Mitral Regurgitation (DELINEATE-MR).
Long A, Haggerty CM, Finer J, Hartzel D, Jing L, Keivani A, Kelsey C, Rocha D, Ruhl J, vanMaanen D, Metser G, Duffy E, Mawson T, Maurer M, Einstein AJ, Beecy A, Kumaraiah D, Homma S, Liu Q, Agarwal V, Lebehn M, Leon M, Hahn R, Elias P, Poterucha TJ. Long A, et al. Among authors: leon m. Circulation. 2024 Jun 17. doi: 10.1161/CIRCULATIONAHA.124.068996. Online ahead of print. Circulation. 2024. PMID: 38881496
3,403 results