Mach RH - Search Results

1

Positron Emission Tomography with [¹⁸F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy.

Gallagher E, Hou C, Zhu Y, Hsieh CJ, Lee H, Li S, Xu K, Henderson P, Chroneos R, Sheldon M, Riley S, Luk KC, Mach RH, McManus MJ. Gallagher E, et al. Among authors: mach rh. Int J Mol Sci. 2024 May 1;25(9):4943. doi: 10.3390/ijms25094943. Int J Mol Sci. 2024. PMID: 38732162 Free PMC article.

2

Development of a Positron Emission Tomography Radiotracer for Imaging Elevated Levels of Superoxide in Neuroinflammation.

Hou C, Hsieh CJ, Li S, Lee H, Graham TJ, Xu K, Weng CC, Doot RK, Chu W, Chakraborty SK, Dugan LL, Mintun MA, Mach RH. Hou C, et al. Among authors: mach rh. ACS Chem Neurosci. 2018 Mar 21;9(3):578-586. doi: 10.1021/acschemneuro.7b00385. Epub 2017 Dec 3. ACS Chem Neurosci. 2018. PMID: 29099578 Free PMC article.

3

Correlation analysis of [¹⁸F]ROStrace using ex vivo autoradiography and dihydroethidium fluorescent imaging in lipopolysaccharide-treated animals.

Weng CC, Carlin S, Hou C, Metz T, Li S, Lee H, Xu K, Makvandi M, Mach RH. Weng CC, et al. Among authors: mach rh. Biochem Biophys Res Commun. 2019 Aug 20;516(2):397-401. doi: 10.1016/j.bbrc.2019.06.062. Epub 2019 Jun 17. Biochem Biophys Res Commun. 2019. PMID: 31221481

4

[¹⁸F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer's disease pathology in APP/PS1 mice.

Hsieh CJ, Hou C, Zhu Y, Lee JY, Kohli N, Gallagher E, Xu K, Lee H, Li S, McManus MJ, Mach RH. Hsieh CJ, et al. Among authors: mach rh. EJNMMI Res. 2022 Jul 27;12(1):43. doi: 10.1186/s13550-022-00914-x. EJNMMI Res. 2022. PMID: 35895177 Free PMC article.

5

Exploration of Diazaspiro Cores as Piperazine Bioisosteres in the Development of σ2 Receptor Ligands.

Xu K, Hsieh CJ, Lee JY, Riad A, Izzo NJ, Look G, Catalano S, Mach RH. Xu K, et al. Among authors: mach rh. Int J Mol Sci. 2022 Jul 27;23(15):8259. doi: 10.3390/ijms23158259. Int J Mol Sci. 2022. PMID: 35897835 Free PMC article.

6

Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D₃-Selective Antagonists.

Kim HY, Lee JY, Hsieh CJ, Taylor M, Luedtke RR, Mach RH. Kim HY, et al. Among authors: mach rh. Int J Mol Sci. 2022 Dec 27;24(1):432. doi: 10.3390/ijms24010432. Int J Mol Sci. 2022. PMID: 36613875 Free PMC article.

7

Correction: [¹⁸F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer's disease pathology in APP/PS1 mice.

Hsieh CJ, Hou C, Zhu Y, Lee JY, Kohli N, Gallagher E, Xu K, Lee H, Li S, McManus MJ, Mach RH. Hsieh CJ, et al. Among authors: mach rh. EJNMMI Res. 2023 Feb 27;13(1):16. doi: 10.1186/s13550-023-00963-w. EJNMMI Res. 2023. PMID: 36847980 Free PMC article. No abstract available.

8

Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search.

Janssen B, Tian G, Lengyel-Zhand Z, Hsieh CJ, Lougee MG, Riad A, Xu K, Hou C, Weng CC, Lopresti BJ, Kim HJ, Pagar VV, Ferrie JJ, Garcia BA, Mathis CA, Luk K, Petersson EJ, Mach RH. Janssen B, et al. Among authors: mach rh. Mol Imaging Biol. 2023 Aug;25(4):704-719. doi: 10.1007/s11307-023-01814-9. Epub 2023 Mar 29. Mol Imaging Biol. 2023. PMID: 36991273

9

A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy.

Kim HY, Chia WK, Hsieh CJ, Saturnino Guarino D, Graham TJA, Lengyel-Zhand Z, Schneider M, Tomita C, Lougee MG, Kim HJ, Pagar VV, Lee H, Hou C, Garcia BA, Petersson EJ, O'Shea J, Kotzbauer PT, Mathis CA, Lee VM, Luk KC, Mach RH. Kim HY, et al. Among authors: mach rh. J Med Chem. 2023 Sep 14;66(17):12185-12202. doi: 10.1021/acs.jmedchem.3c00779. Epub 2023 Aug 31. J Med Chem. 2023. PMID: 37651366

10

Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules.

Hsieh CJ, Ferrie JJ, Xu K, Lee I, Graham TJA, Tu Z, Yu J, Dhavale D, Kotzbauer P, Petersson EJ, Mach RH. Hsieh CJ, et al. Among authors: mach rh. ACS Chem Neurosci. 2018 Nov 21;9(11):2521-2527. doi: 10.1021/acschemneuro.8b00177. Epub 2018 May 16. ACS Chem Neurosci. 2018. PMID: 29750499 Free PMC article.

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