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Polymorphisms in the NFkB, TNF-alpha, IL-1beta, and IL-18 pathways are associated with response to anti-TNF therapy in Danish patients with inflammatory bowel disease.
Bank S, Julsgaard M, Abed OK, Burisch J, Broder Brodersen J, Pedersen NK, Gouliaev A, Ajan R, Nytoft Rasmussen D, Honore Grauslund C, Roug S, Galsgaard J, Sprogøe Høyer Finsen D, Lindby K; Danish IBD Genetics Working Group; Sørensen J, Larsen L, Rohr Andersen M, Brandslund I, Thomassen M, Green A, Bo Bojesen A, Bek Sørensen S, Vogel U, Andersen V. Bank S, et al. Aliment Pharmacol Ther. 2019 Apr;49(7):890-903. doi: 10.1111/apt.15187. Epub 2019 Feb 27. Aliment Pharmacol Ther. 2019. PMID: 30811631
Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis.
Sode J, Bank S, Vogel U, Andersen PS, Sørensen SB, Bojesen AB, Andersen MR, Brandslund I, Dessau RB, Hoffmann HJ, Glintborg B, Hetland ML, Locht H, Heegaard NH, Andersen V. Sode J, et al. BMC Med Genet. 2018 Sep 12;19(1):165. doi: 10.1186/s12881-018-0680-z. BMC Med Genet. 2018. PMID: 30208882 Free PMC article.
Plasma MicroRNA Profiles in Patients with Early Rheumatoid Arthritis Responding to Adalimumab plus Methotrexate vs Methotrexate Alone: A Placebo-controlled Clinical Trial.
Sode J, Krintel SB, Carlsen AL, Hetland ML, Johansen JS, Hørslev-Petersen K, Stengaard-Pedersen K, Ellingsen T, Burton M, Junker P, Østergaard M, Heegaard NHH. Sode J, et al. J Rheumatol. 2018 Jan;45(1):53-61. doi: 10.3899/jrheum.170266. Epub 2017 Nov 15. J Rheumatol. 2018. PMID: 29142030 Clinical Trial.
Genetically determined high activity of IL-12 and IL-18 in ulcerative colitis and TLR5 in Crohns disease were associated with non-response to anti-TNF therapy.
Bank S, Andersen PS, Burisch J, Pedersen N, Roug S, Galsgaard J, Turino SY, Brodersen JB, Rashid S, Rasmussen BK, Avlund S, Olesen TB, Hoffmann HJ, Nexø BA, Sode J, Vogel U, Andersen V. Bank S, et al. Among authors: sode j. Pharmacogenomics J. 2018 Jan;18(1):87-97. doi: 10.1038/tpj.2016.84. Epub 2017 Jan 31. Pharmacogenomics J. 2018. PMID: 28139755
Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort.
Bank S, Andersen PS, Burisch J, Pedersen N, Roug S, Galsgaard J, Ydegaard Turino S, Brodersen JB, Rashid S, Kaiser Rasmussen B, Avlund S, Bastholm Olesen T, Hoffmann HJ, Andersen Nexø B, Sode J, Vogel U, Andersen V. Bank S, et al. Among authors: sode j. PLoS One. 2015 Dec 23;10(12):e0145302. doi: 10.1371/journal.pone.0145302. eCollection 2015. PLoS One. 2015. PMID: 26698117 Free PMC article.
72 results