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ML345, A Small-Molecule Inhibitor of the Insulin-Degrading Enzyme (IDE).
Bannister TD, Wang H, Abdul-Hay SO, Masson A, Madoux F, Ferguson J, Mercer BA, Schurer S, Zuhl A, Cravatt BF, Leissring MA, Hodder P. Bannister TD, et al. Among authors: mercer ba. 2012 Dec 17 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Dec 17 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23833801 Free Books & Documents. Review.
ML322, A Small Molecule Inhibitor of Dimerization of the Core Protein of Hepatitis C Virus (HCV).
Kota S, Madoux F, Chase P, Takahashi V, Liu Q, Mercer BA, Cameron M, Strosberg AD, Roush W, Hodder P. Kota S, et al. Among authors: mercer ba. 2012 Dec 17 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Dec 17 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23833796 Free Books & Documents. Review.
ML302, a Novel Beta-lactamase (BLA) Inhibitor.
Spicer T, Minond D, Enogieru I, Saldanha SA, Allais C, Liu Q, Mercer BA, Roush WR, Hodder P. Spicer T, et al. Among authors: mercer ba. 2012 Apr 16 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Apr 16 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762954 Free Books & Documents. Review.
Identification of Selective Agonists of the Transient Receptor Potential Channels 3 (TRPML3).
Saldanha SA, Grimm C, Allais C, Smith E, Ouizem S, Mercer BA, Roush WR, Heller S, Hodder P. Saldanha SA, et al. Among authors: mercer ba. 2012 Mar 21 [updated 2013 Sep 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Mar 21 [updated 2013 Sep 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24260779 Free Books & Documents. Review.
ML346: A Novel Modulator of Proteostasis for Protein Conformational Diseases.
Calamini B, Silva MC, Madoux F, Hutt DM, Khanna S, Chalfant MA, Allais C, Ouizem S, Saldanha SA, Ferguson J, Mercer BA, Michael C, Tait BD, Garza D, Balch WE, Roush WR, Morimoto RI, Hodder P. Calamini B, et al. Among authors: mercer ba. 2012 Dec 17 [updated 2013 Apr 5]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Dec 17 [updated 2013 Apr 5]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23833797 Free Books & Documents. Review.
ML328: A Novel Dual Inhibitor of Bacterial AddAB and RecBCD Helicase-nuclease DNA Repair Enzymes.
Bannister TD, Nair R, Spicer T, Fernandez Vega V, Eberhart C, Mercer BA, Cameron M, Schurer S, Amundsen SK, Karabulut A, Londoño LM, Smith GR, Hodder P. Bannister TD, et al. Among authors: mercer ba. 2012 Dec 17 [updated 2013 Apr 5]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Dec 17 [updated 2013 Apr 5]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23833795 Free Books & Documents. Review.
Identification of Small Molecule Inhibitors of Wee1 Degradation and Mitotic Entry.
Simanski S, Madoux F, Rahaim RJ, Chase P, Schurer S, Cameron M, Mercer BA, Hodder P, Roush WR, Ayad NG. Simanski S, et al. Among authors: mercer ba. 2010 Sep 1 [updated 2013 Mar 22]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2010 Sep 1 [updated 2013 Mar 22]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762957 Free Books & Documents. Review.
Identification of a novel selective inverse agonist probe and analogs for the Retinoic acid receptor-related Orphan Receptor Alpha (RORα).
Kumar N, Nuhant P, Solt LA, Conkright JJ, Wang Y, Istrate MA, Busby SA, Ruben DGO, Burris TP, Cameron M, Mercer BA, Hodder P, Roush WR, Rosen H, Griffin PR. Kumar N, et al. Among authors: mercer ba. 2010 Sep 1 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2010 Sep 1 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762959 Free Books & Documents. Review.
Identification of a novel selective inverse agonist probe and analogs for the Retinoic acid receptor-related Orphan Receptor Gamma (RORγ).
Kumar N, Kamenecka T, Lyda B, Khan P, Chang MR, Garcia-Ordonez RD, Cameron M, Ferguson J, Mercer BA, Hodder P, Rosen H, Griffin PR. Kumar N, et al. Among authors: mercer ba. 2012 Apr 16 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Apr 16 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762937 Free Books & Documents. Review.
ML311: A Small Molecule that Potently and Selectively Disrupts the Protein-Protein Interaction of Mcl-1 and Bim: A Probe for Studying Lymphoid Tumorigenesis.
Bannister T, Koenig M, He Y, Mishra J, Spicer T, Minond D, Saldanha A, Mercer BA, Cameron M, Lena R, Carlson N, Richard D, Cardone M, Hodder P. Bannister T, et al. Among authors: mercer ba. 2012 Apr 16 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Apr 16 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762927 Free Books & Documents. Review.
35 results