Gosden J - Search Results

1

Receptor binding and functional evidence suggest that postsynaptic alpha 2-adrenoceptors in rat brain are of the alpha 2D subtype.

Heal DJ, Cheetham SC, Butler SA, Gosden J, Prow MR, Buckett WR. Heal DJ, et al. Among authors: gosden j. Eur J Pharmacol. 1995 Apr 24;277(2-3):215-21. doi: 10.1016/0014-2999(95)00078-y. Eur J Pharmacol. 1995. PMID: 7493611

2

A comparison of various antidepressant drugs demonstrates rapid desensitisation of alpha 2-adrenoceptors exclusively by sibutramine hydrochloride.

Heal DJ, Prow MR, Gosden J, Luscombe GP, Buckett WR. Heal DJ, et al. Among authors: gosden j. Psychopharmacology (Berl). 1992;107(4):497-502. doi: 10.1007/BF02245262. Psychopharmacology (Berl). 1992. PMID: 1351304

3

A comparison of the effects of sibutramine hydrochloride, bupropion and methamphetamine on dopaminergic function: evidence that dopamine is not a pharmacological target for sibutramine.

Heal DJ, Frankland AT, Gosden J, Hutchins LJ, Prow MR, Luscombe GP, Buckett WR. Heal DJ, et al. Among authors: gosden j. Psychopharmacology (Berl). 1992;107(2-3):303-9. doi: 10.1007/BF02245152. Psychopharmacology (Berl). 1992. PMID: 1615130

4

Mediation of the antidepressant-like effect of 8-OH-DPAT in mice by postsynaptic 5-HT1A receptors.

Luscombe GP, Martin KF, Hutchins LJ, Gosden J, Heal DJ. Luscombe GP, et al. Among authors: gosden j. Br J Pharmacol. 1993 Mar;108(3):669-77. doi: 10.1111/j.1476-5381.1993.tb12859.x. Br J Pharmacol. 1993. PMID: 8467355 Free PMC article.

5

A review of late-stage CNS drug candidates for the treatment of obesity.

Heal DJ, Gosden J, Smith SL. Heal DJ, et al. Among authors: gosden j. Int J Obes (Lond). 2013 Jan;37(1):107-17. doi: 10.1038/ijo.2012.26. Epub 2012 Mar 13. Int J Obes (Lond). 2013. PMID: 22410963 Review.

6

Lisdexamfetamine and immediate release d-amfetamine - differences in pharmacokinetic/pharmacodynamic relationships revealed by striatal microdialysis in freely-moving rats with simultaneous determination of plasma drug concentrations and locomotor activity.

Rowley HL, Kulkarni R, Gosden J, Brammer R, Hackett D, Heal DJ. Rowley HL, et al. Among authors: gosden j. Neuropharmacology. 2012 Nov;63(6):1064-74. doi: 10.1016/j.neuropharm.2012.07.008. Epub 2012 Jul 14. Neuropharmacology. 2012. PMID: 22796358

7

The effects in rats of lisdexamfetamine in combination with olanzapine on mesocorticolimbic dopamine efflux, striatal dopamine D2 receptor occupancy and stimulus generalization to a D-amphetamine cue.

Hutson PH, Rowley HL, Gosden J, Kulkarni RS, Slater N, Love PL, Wang Y, Heal D. Hutson PH, et al. Among authors: gosden j. Neuropharmacology. 2016 Feb;101:24-35. doi: 10.1016/j.neuropharm.2015.09.014. Epub 2015 Sep 16. Neuropharmacology. 2016. PMID: 26384654

8

Experimental strategies to discover and develop the next generation of psychedelics and entactogens as medicines.

Heal DJ, Gosden J, Smith SL, Atterwill CK. Heal DJ, et al. Among authors: gosden j. Neuropharmacology. 2023 Mar 1;225:109375. doi: 10.1016/j.neuropharm.2022.109375. Epub 2022 Dec 16. Neuropharmacology. 2023. PMID: 36529260 Free article. Review.

9

Stimulant prodrugs: A pharmacological and clinical assessment of their role in treating ADHD and binge-eating disorder.

Heal DJ, Gosden J, Smith SL. Heal DJ, et al. Among authors: gosden j. Adv Pharmacol. 2024;99:251-286. doi: 10.1016/bs.apha.2023.10.002. Epub 2023 Oct 25. Adv Pharmacol. 2024. PMID: 38467483 Review.

10

New Drugs to Treat ADHD: Opportunities and Challenges in Research and Development.

Heal DJ, Gosden J, Smith SL. Heal DJ, et al. Among authors: gosden j. Curr Top Behav Neurosci. 2022;57:79-126. doi: 10.1007/7854_2022_332. Curr Top Behav Neurosci. 2022. PMID: 35507283 Review.

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