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Derivatives of (-)-7-methyl-2-(5-(pyridinyl)pyridin-3-yl)-7-azabicyclo[2.2.1]heptane are potential ligands for positron emission tomography imaging of extrathalamic nicotinic acetylcholine receptors.
Gao Y, Horti AG, Kuwabara H, Ravert HT, Hilton J, Holt DP, Kumar A, Alexander M, Endres CJ, Wong DF, Dannals RF. Gao Y, et al. Among authors: hilton j. J Med Chem. 2007 Aug 9;50(16):3814-24. doi: 10.1021/jm070224t. Epub 2007 Jul 13. J Med Chem. 2007. PMID: 17629263
Use of positron emission tomography to study AT1 receptor regulation in vivo.
Szabo Z, Speth RC, Brown PR, Kerenyi L, Kao PF, Mathews WB, Ravert HT, Hilton J, Rauseo P, Dannals RF, Zheng W, Lee S, Sandberg K. Szabo Z, et al. Among authors: hilton j. J Am Soc Nephrol. 2001 Jul;12(7):1350-1358. doi: 10.1681/ASN.V1271350. J Am Soc Nephrol. 2001. PMID: 11423564
Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2.1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging properties.
Gao Y, Kuwabara H, Spivak CE, Xiao Y, Kellar K, Ravert HT, Kumar A, Alexander M, Hilton J, Wong DF, Dannals RF, Horti AG. Gao Y, et al. Among authors: hilton j. J Med Chem. 2008 Aug 14;51(15):4751-64. doi: 10.1021/jm800323d. Epub 2008 Jul 8. J Med Chem. 2008. PMID: 18605717
951 results