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4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro.
Woods JM, Bethell RC, Coates JA, Healy N, Hiscox SA, Pearson BA, Ryan DM, Ticehurst J, Tilling J, Walcott SM, et al. Woods JM, et al. Among authors: hiscox sa. Antimicrob Agents Chemother. 1993 Jul;37(7):1473-9. doi: 10.1128/AAC.37.7.1473. Antimicrob Agents Chemother. 1993. PMID: 8363379 Free PMC article.
Role of neuraminidase in influenza virus-induced apoptosis.
Morris SJ, Price GE, Barnett JM, Hiscox SA, Smith H, Sweet C. Morris SJ, et al. Among authors: hiscox sa. J Gen Virol. 1999 Jan;80 ( Pt 1):137-146. doi: 10.1099/0022-1317-80-1-137. J Gen Virol. 1999. PMID: 9934696