Pearce BC - Search Results

1

Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Parker RA, et al. Among authors: pearce bc. J Biol Chem. 1993 May 25;268(15):11230-8. J Biol Chem. 1993. PMID: 8388388 Free article.

2

Hypocholesterolemic activity of synthetic and natural tocotrienols.

Pearce BC, Parker RA, Deason ME, Qureshi AA, Wright JJ. Pearce BC, et al. J Med Chem. 1992 Oct 2;35(20):3595-606. doi: 10.1021/jm00098a002. J Med Chem. 1992. PMID: 1433170

3

Inhibitors of cholesterol biosynthesis. 2. Hypocholesterolemic and antioxidant activities of benzopyran and tetrahydronaphthalene analogues of the tocotrienols.

Pearce BC, Parker RA, Deason ME, Dischino DD, Gillespie E, Qureshi AA, Volk K, Wright JJ. Pearce BC, et al. J Med Chem. 1994 Feb 18;37(4):526-41. doi: 10.1021/jm00030a012. J Med Chem. 1994. PMID: 8120870

4

Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains.

Meanwell NA, Pearce BC, Roth HR, Smith EC, Wedding DL, Wright JJ, Buchanan JO, Baryla UM, Gamberdella M, Gillespie E, et al. Meanwell NA, et al. Among authors: pearce bc. J Med Chem. 1992 Jul 10;35(14):2672-87. doi: 10.1021/jm00092a019. J Med Chem. 1992. PMID: 1321910

5

Response of hypercholesterolemic subjects to administration of tocotrienols.

Qureshi AA, Bradlow BA, Brace L, Manganello J, Peterson DM, Pearce BC, Wright JJ, Gapor A, Elson CE. Qureshi AA, et al. Among authors: pearce bc. Lipids. 1995 Dec;30(12):1171-7. doi: 10.1007/BF02536620. Lipids. 1995. PMID: 8614309 Clinical Trial.

6

Inhibitors of HIV-1 attachment. Part 3: A preliminary survey of the effect of structural variation of the benzamide moiety on antiviral activity.

Meanwell NA, Wallace OB, Wang H, Deshpande M, Pearce BC, Trehan A, Yeung KS, Qiu Z, Wright JJ, Robinson BA, Gong YF, Wang HG, Spicer TP, Blair WS, Shi PY, Lin PF. Meanwell NA, et al. Among authors: pearce bc. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5136-9. doi: 10.1016/j.bmcl.2009.07.027. Epub 2009 Jul 10. Bioorg Med Chem Lett. 2009. PMID: 19632112

7

Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens.

Qureshi AA, Pearce BC, Nor RM, Gapor A, Peterson DM, Elson CE. Qureshi AA, et al. Among authors: pearce bc. J Nutr. 1996 Feb;126(2):389-94. doi: 10.1093/jn/126.2.389. J Nutr. 1996. PMID: 8632210

8

1,2-Benzisothiazol-3-one 1,1-dioxide inhibitors of human mast cell tryptase.

Combrink KD, Gülgeze HB, Meanwell NA, Pearce BC, Zulan P, Bisacchi GS, Roberts DG, Stanley P, Seiler SM. Combrink KD, et al. Among authors: pearce bc. J Med Chem. 1998 Nov 19;41(24):4854-60. doi: 10.1021/jm9804580. J Med Chem. 1998. PMID: 9822554

9

Salicylamide inhibitors of influenza virus fusion.

Combrink KD, Gulgeze HB, Yu KL, Pearce BC, Trehan AK, Wei J, Deshpande M, Krystal M, Torri A, Luo G, Cianci C, Danetz S, Tiley L, Meanwell NA. Combrink KD, et al. Among authors: pearce bc. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1649-52. doi: 10.1016/s0960-894x(00)00335-8. Bioorg Med Chem Lett. 2000. PMID: 10937716

10

Novel quinolizidine salicylamide influenza fusion inhibitors.

Yu KL, Ruediger E, Luo G, Cianci C, Danetz S, Tiley L, Trehan AK, Monkovic I, Pearce B, Martel A, Krystal M, Meanwell NA. Yu KL, et al. Bioorg Med Chem Lett. 1999 Aug 2;9(15):2177-80. doi: 10.1016/s0960-894x(99)00361-3. Bioorg Med Chem Lett. 1999. PMID: 10465540

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