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Serine- and threonine-rich domain regulates internalization of muscarinic cholinergic receptors.
Moro O, Lameh J, Sadée W. Moro O, et al. Among authors: lameh j. J Biol Chem. 1993 Apr 5;268(10):6862-5. J Biol Chem. 1993. PMID: 8463213 Free article.
With the use of deletion mutations, we previously showed that a small region in the middle of the third intracellular loop (i3) appears to be required for the agonist-induced internalization of the Hm1 muscarinic cholinergic receptor (Lameh, J., Philip, M., Sharma, …
With the use of deletion mutations, we previously showed that a small region in the middle of the third intracellular loop (i3) appears to b …
Activating and inactivating mutations in N- and C-terminal i3 loop junctions of muscarinic acetylcholine Hm1 receptors.
Högger P, Shockley MS, Lameh J, Sadée W. Högger P, et al. Among authors: lameh j. J Biol Chem. 1995 Mar 31;270(13):7405-10. doi: 10.1074/jbc.270.13.7405. J Biol Chem. 1995. PMID: 7706286 Free article.
We had previously constructed two triple point alanine mutants of the i3 junction of the muscarinic Hm1 receptor, W209A/I211A/Y212A and E360A/K362A/T366A, which are defective in mediating carbachol stimulation of phosphatidylinositol (PI) turnover (Moro, O., Lameh, J …
We had previously constructed two triple point alanine mutants of the i3 junction of the muscarinic Hm1 receptor, W209A/I211A/Y212A and E360 …
Overlapping multi-site domains of the muscarinic cholinergic Hm1 receptor involved in signal transduction and sequestration.
Moro O, Shockley MS, Lameh J, Sadée W. Moro O, et al. Among authors: lameh j. J Biol Chem. 1994 Mar 4;269(9):6651-5. J Biol Chem. 1994. PMID: 8120019 Free article.
Using these multiple alanine point mutants of Hm1, we had previously identified several receptor domains in the intracellular loops i1-3 that play a role in coupling to phosphatidyl inositol turnover, most notably, a lipophilic residue, Leu-131, in the conserved i2 loop domain DR …
Using these multiple alanine point mutants of Hm1, we had previously identified several receptor domains in the intracellular loops i1-3 tha …
50 results