Asin KE - Search Results

1

ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease.

Shiosaki K, Jenner P, Asin KE, Britton DR, Lin CW, Michaelides M, Smith L, Bianchi B, Didomenico S, Hodges L, Hong Y, Mahan L, Mikusa J, Miller T, Nikkel A, Stashko M, Witte D, Williams M. Shiosaki K, et al. Among authors: asin ke. J Pharmacol Exp Ther. 1996 Jan;276(1):150-60. J Pharmacol Exp Ther. 1996. PMID: 8558425

2

Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636.

Lin CW, Bianchi BR, Miller TR, Stashko MA, Wang SS, Curzon P, Bednarz L, Asin KE, Britton DR. Lin CW, et al. Among authors: asin ke. J Pharmacol Exp Ther. 1996 Mar;276(3):1022-9. J Pharmacol Exp Ther. 1996. PMID: 8786531

3

MK-801 differentially affects dopamine D1 and D2 receptor agonist-induced behavioral tolerance and desensitization.

Asin KE, Bednarz L, Nikkel AL. Asin KE, et al. Brain Res. 1996 Jun 24;725(1):67-74. doi: 10.1016/0006-8993(96)00348-4. Brain Res. 1996. PMID: 8828587

4

Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431.

Shiosaki K, Asin KE, Britton DR, Giardina WJ, Bednarz L, Mahan L, Mikusa J, Nikkel A, Wismer C. Shiosaki K, et al. Among authors: asin ke. Eur J Pharmacol. 1996 Dec 19;317(2-3):183-90. doi: 10.1016/s0014-2999(96)00718-2. Eur J Pharmacol. 1996. PMID: 8997599

5

The selective dopamine D1 receptor agonist A-86929 maintains efficacy with repeated treatment in rodent and primate models of Parkinson's disease.

Asin KE, Domino EF, Nikkel A, Shiosaki K. Asin KE, et al. J Pharmacol Exp Ther. 1997 Apr;281(1):454-9. J Pharmacol Exp Ther. 1997. PMID: 9103530

6

Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo.

Michaelides MR, Hong Y, DiDomenico S Jr, Bayburt EK, Asin KE, Britton DR, Lin CW, Shiosaki K. Michaelides MR, et al. Among authors: asin ke. J Med Chem. 1997 May 23;40(11):1585-99. doi: 10.1021/jm970038v. J Med Chem. 1997. PMID: 9171869

7

(5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-azacyclopent-1- ena[c]-phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintains behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431).

Michaelides MR, Hong Y, DiDomenico S Jr, Asin KE, Britton DR, Lin CW, Williams M, Shiosaki K. Michaelides MR, et al. Among authors: asin ke. J Med Chem. 1995 Sep 1;38(18):3445-7. doi: 10.1021/jm00018a002. J Med Chem. 1995. PMID: 7658429 No abstract available.

8

Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa.

Asin KE, Bednarz L, Nikkel A, Perner R. Asin KE, et al. J Pharmacol Exp Ther. 1995 Jun;273(3):1483-90. J Pharmacol Exp Ther. 1995. PMID: 7791123

9

A68930: a potent agonist specific for the dopamine D1 receptor.

Kebabian JW, DeNinno MP, Schoenleber R, MacKenzie R, Britton DR, Asin KE. Kebabian JW, et al. Among authors: asin ke. Neurochem Int. 1992 Mar;20 Suppl:157S-160S. doi: 10.1016/0197-0186(92)90230-o. Neurochem Int. 1992. PMID: 1365416

10

Repeated D1 receptor agonist treatment blocks cocaine-induced locomotor activity and c-fos expression.

Asin KE, Nikkel AL, Wirtshafter D. Asin KE, et al. Brain Res. 1994 Feb 21;637(1-2):342-4. doi: 10.1016/0006-8993(94)91258-0. Brain Res. 1994. PMID: 7910104

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