Keating MT - Search Results

1

Molecular genetic insights into cardiovascular disease.

Keating MT, Sanguinetti MC. Keating MT, et al. Science. 1996 May 3;272(5262):681-5. doi: 10.1126/science.272.5262.681. Science. 1996. PMID: 8614827 Review.

2

Pathophysiology of ion channel mutations.

Keating MT, Sanguinetti MC. Keating MT, et al. Curr Opin Genet Dev. 1996 Jun;6(3):326-33. doi: 10.1016/s0959-437x(96)80010-4. Curr Opin Genet Dev. 1996. PMID: 8791523 Review.

3

Compound mutations: a common cause of severe long-QT syndrome.

Westenskow P, Splawski I, Timothy KW, Keating MT, Sanguinetti MC. Westenskow P, et al. Among authors: keating mt. Circulation. 2004 Apr 20;109(15):1834-41. doi: 10.1161/01.CIR.0000125524.34234.13. Epub 2004 Mar 29. Circulation. 2004. PMID: 15051636

4

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.

Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT. Splawski I, et al. Among authors: keating mt. Cell. 2004 Oct 1;119(1):19-31. doi: 10.1016/j.cell.2004.09.011. Cell. 2004. PMID: 15454078 Free article.

5

Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations.

Splawski I, Timothy KW, Decher N, Kumar P, Sachse FB, Beggs AH, Sanguinetti MC, Keating MT. Splawski I, et al. Among authors: keating mt. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8089-96; discussion 8086-8. doi: 10.1073/pnas.0502506102. Epub 2005 Apr 29. Proc Natl Acad Sci U S A. 2005. PMID: 15863612 Free PMC article.

6

Impaired interaction between the slide helix and the C-terminus of Kir2.1: a novel mechanism of Andersen syndrome.

Decher N, Renigunta V, Zuzarte M, Soom M, Heinemann SH, Timothy KW, Keating MT, Daut J, Sanguinetti MC, Splawski I. Decher N, et al. Among authors: keating mt. Cardiovasc Res. 2007 Sep 1;75(4):748-57. doi: 10.1016/j.cardiores.2007.05.010. Epub 2007 May 10. Cardiovasc Res. 2007. PMID: 17568571

7

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel.

Sanguinetti MC, Jiang C, Curran ME, Keating MT. Sanguinetti MC, et al. Among authors: keating mt. Cell. 1995 Apr 21;81(2):299-307. doi: 10.1016/0092-8674(95)90340-2. Cell. 1995. PMID: 7736582 Free article.

8

Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides.

Spector PS, Curran ME, Keating MT, Sanguinetti MC. Spector PS, et al. Among authors: keating mt. Circ Res. 1996 Mar;78(3):499-503. doi: 10.1161/01.res.78.3.499. Circ Res. 1996. PMID: 8593709

9

Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.

Sanguinetti MC, Curran ME, Spector PS, Keating MT. Sanguinetti MC, et al. Among authors: keating mt. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2208-12. doi: 10.1073/pnas.93.5.2208. Proc Natl Acad Sci U S A. 1996. PMID: 8700910 Free PMC article.

10

Fast inactivation causes rectification of the IKr channel.

Spector PS, Curran ME, Zou A, Keating MT, Sanguinetti MC. Spector PS, et al. Among authors: keating mt. J Gen Physiol. 1996 May;107(5):611-9. doi: 10.1085/jgp.107.5.611. J Gen Physiol. 1996. PMID: 8740374 Free PMC article.

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