Fernandez-Salguero P - Search Results

1

Role of CYP2E1 in the hepatotoxicity of acetaminophen.

Lee SS, Buters JT, Pineau T, Fernandez-Salguero P, Gonzalez FJ. Lee SS, et al. J Biol Chem. 1996 May 17;271(20):12063-7. doi: 10.1074/jbc.271.20.12063. J Biol Chem. 1996. PMID: 8662637 Free article.

2

Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene.

Miyata M, Kudo G, Lee YH, Yang TJ, Gelboin HV, Fernandez-Salguero P, Kimura S, Gonzalez FJ. Miyata M, et al. J Biol Chem. 1999 Aug 20;274(34):23963-8. doi: 10.1074/jbc.274.34.23963. J Biol Chem. 1999. PMID: 10446164 Free article.

3

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators.

Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ. Lee SS, et al. Mol Cell Biol. 1995 Jun;15(6):3012-22. doi: 10.1128/MCB.15.6.3012. Mol Cell Biol. 1995. PMID: 7539101 Free PMC article.

4

Targeted disruption of specific cytochromes P450 and xenobiotic receptor genes.

Fernandez-Salguero PM, Gonzalez FJ. Fernandez-Salguero PM, et al. Methods Enzymol. 1996;272:412-30. doi: 10.1016/s0076-6879(96)72046-3. Methods Enzymol. 1996. PMID: 8791800 No abstract available.

5

Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.

Fernandez-Salguero PM, Hilbert DM, Rudikoff S, Ward JM, Gonzalez FJ. Fernandez-Salguero PM, et al. Toxicol Appl Pharmacol. 1996 Sep;140(1):173-9. doi: 10.1006/taap.1996.0210. Toxicol Appl Pharmacol. 1996. PMID: 8806883

6

Aryl hydrocarbon receptor knockout mice (AHR-/-) exhibit liver retinoid accumulation and reduced retinoic acid metabolism.

Andreola F, Fernandez-Salguero PM, Chiantore MV, Petkovich MP, Gonzalez FJ, De Luca LM. Andreola F, et al. Cancer Res. 1997 Jul 15;57(14):2835-8. Cancer Res. 1997. PMID: 9230184

7

Lesions of aryl-hydrocarbon receptor-deficient mice.

Fernandez-Salguero PM, Ward JM, Sundberg JP, Gonzalez FJ. Fernandez-Salguero PM, et al. Vet Pathol. 1997 Nov;34(6):605-14. doi: 10.1177/030098589703400609. Vet Pathol. 1997. PMID: 9396142

8

The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-beta and apoptosis.

Zaher H, Fernandez-Salguero PM, Letterio J, Sheikh MS, Fornace AJ Jr, Roberts AB, Gonzalez FJ. Zaher H, et al. Mol Pharmacol. 1998 Aug;54(2):313-21. doi: 10.1124/mol.54.2.313. Mol Pharmacol. 1998. PMID: 9687573

9

Diagnostic analysis, clinical importance and molecular basis of dihydropyrimidine dehydrogenase deficiency.

Gonzalez FJ, Fernandez-Salguero P. Gonzalez FJ, et al. Trends Pharmacol Sci. 1995 Oct;16(10):325-7. doi: 10.1016/s0165-6147(00)89065-3. Trends Pharmacol Sci. 1995. PMID: 7491709 Review. No abstract available.

10

The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis.

Fernandez-Salguero P, Gonzalez FJ. Fernandez-Salguero P, et al. Pharmacogenetics. 1995;5 Spec No:S123-8. doi: 10.1097/00008571-199512001-00013. Pharmacogenetics. 1995. PMID: 7581481 Review.

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