Deficiency of 5'-deoxy-5'-methylthioadenosine phosphorylase activity in malignancy. Absence of the protein in human enzyme-deficient cell lines.
Della Ragione F, Oliva A, Palumbo R, Russo GL, Gragnaniello V, Zappia V.
Della Ragione F, et al. Among authors: oliva a.
Biochem J. 1992 Jan 15;281 ( Pt 2)(Pt 2):533-8. doi: 10.1042/bj2810533.
Biochem J. 1992.
PMID: 1736901
Free PMC article.
The absence of 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAase) activity in malignant cells, and the putative localization of its gene, suggest that this enzyme deficiency might be due to a genomic alteration also involving a tumour-suppressor gene. We studied …
The absence of 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAase) activity in malignant cells, and the putative localization of its gene …