Elder JS - Search Results

1

The chemistry of pseudomonic acid. 17. Dual-action C-1 oxazole derivatives of pseudomonic acid having an extended spectrum of antibacterial activity.

Broom NJ, Cassels R, Cheng HY, Elder JS, Hannan PC, Masson N, O'Hanlon PJ, Pope A, Wilson JM. Broom NJ, et al. Among authors: elder js. J Med Chem. 1996 Aug 30;39(18):3596-600. doi: 10.1021/jm950882q. J Med Chem. 1996. PMID: 8784459

2

Chemistry of pseudomonic acid. Part 16. Aryl and heteroaryl ketone derivatives of monic acid.

Abson A, Broom NJ, Coates PA, Elder JS, Forrest AK, Hannan PC, Hicks AJ, O'Hanlon PJ, Masson ND, Pearson ND, Pons JE, Wilson JM. Abson A, et al. Among authors: elder js. J Antibiot (Tokyo). 1996 Apr;49(4):390-4. doi: 10.7164/antibiotics.49.390. J Antibiot (Tokyo). 1996. PMID: 8642004 Free article.

3

Synthesis and antibacterial properties of beta-diketone acrylate bioisosteres of pseudomonic acid A.

Bennett I, Broom NJ, Cassels R, Elder JS, Masson ND, O'Hanlon PJ. Bennett I, et al. Among authors: elder js. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1847-52. doi: 10.1016/s0960-894x(99)00296-6. Bioorg Med Chem Lett. 1999. PMID: 10406653

4

The chemistry of pseudomonic acid. Part 14. Synthesis and in vivo biological activity of heterocyclyl substituted oxazole derivatives.

Broom NJ, Elder JS, Hannan PC, Pons JE, O'Hanlon PJ, Walker G, Wilson J, Woodall P. Broom NJ, et al. Among authors: elder js. J Antibiot (Tokyo). 1995 Nov;48(11):1336-44. doi: 10.7164/antibiotics.48.1336. J Antibiot (Tokyo). 1995. PMID: 8557577 Free article.

5

Nanomolar inhibitors of Staphylococcus aureus methionyl tRNA synthetase with potent antibacterial activity against gram-positive pathogens.

Jarvest RL, Berge JM, Berry V, Boyd HF, Brown MJ, Elder JS, Forrest AK, Fosberry AP, Gentry DR, Hibbs MJ, Jaworski DD, O'Hanlon PJ, Pope AJ, Rittenhouse S, Sheppard RJ, Slater-Radosti C, Worby A. Jarvest RL, et al. Among authors: elder js. J Med Chem. 2002 May 9;45(10):1959-62. doi: 10.1021/jm025502x. J Med Chem. 2002. PMID: 11985462

6

Optimisation of aryl substitution leading to potent methionyl tRNA synthetase inhibitors with excellent gram-positive antibacterial activity.

Jarvest RL, Berge JM, Brown MJ, Brown P, Elder JS, Forrest AK, Houge-Frydrych CS, O'Hanlon PJ, McNair DJ, Rittenhouse S, Sheppard RJ. Jarvest RL, et al. Among authors: elder js. Bioorg Med Chem Lett. 2003 Feb 24;13(4):665-8. doi: 10.1016/s0960-894x(02)01027-2. Bioorg Med Chem Lett. 2003. PMID: 12639554

7

Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues.

Jarvest RL, Armstrong SA, Berge JM, Brown P, Elder JS, Brown MJ, Copley RC, Forrest AK, Hamprecht DW, O'Hanlon PJ, Mitchell DJ, Rittenhouse S, Witty DR. Jarvest RL, et al. Among authors: elder js. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3937-41. doi: 10.1016/j.bmcl.2004.05.070. Bioorg Med Chem Lett. 2004. PMID: 15225702

8

Structure-activity relationships of some arylglycine analogues and catechol isosteres of BRL 36650, a 6 alpha-formamido penicillin.

Best DJ, Burton G, Davies DT, Elder JS, Smale TC, Southgate R, Stachulski AV, Basker MJ, Knott SJ. Best DJ, et al. Among authors: elder js. J Antibiot (Tokyo). 1990 May;43(5):574-7. doi: 10.7164/antibiotics.43.574. J Antibiot (Tokyo). 1990. PMID: 2358408 Free article. No abstract available.

9

Emergence of the natural history of Myhre syndrome: 47 patients evaluated in the Massachusetts General Hospital Myhre Syndrome Clinic (2016-2023).

Lin AE, Scimone ER, Thom RP, Balaguru D, Kinane TB, Moschovis PP, Cohen MS, Tan W, Hague CD, Dannheim K, Levitsky LL, Lilly E, DiGiacomo DV, Masse KM, Kadzielski SM, Zar-Kessler CA, Ginns LC, Neumeyer AM, Colvin MK, Elder JS, Learn CP, Mou H, Weagle KM, Buch KA, Butler WE, Alhadid K, Musolino PL, Sultana S, Bandyopadhyay D, Rapalino O, Peacock ZS, Chou EL, Heidary G, Dorfman AT, Morris SA, Bergin JD, Rayment JH, Schimmenti LA, Lindsay ME; MGH Myhre Syndrome Study Group. Lin AE, et al. Among authors: elder js. Am J Med Genet A. 2024 May 23:e63638. doi: 10.1002/ajmg.a.63638. Online ahead of print. Am J Med Genet A. 2024. PMID: 38779990

10

Awake neuraxial anesthesia for infants undergoing infraumbilical surgery.

Chen AL, Elder JS, Liu CA. Chen AL, et al. Among authors: elder js. Paediatr Anaesth. 2023 Apr;33(4):324-325. doi: 10.1111/pan.14606. Epub 2022 Dec 4. Paediatr Anaesth. 2023. PMID: 36424879 No abstract available.

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