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Transgenic approaches to model Alzheimer's disease.
Sommer B, Sturchler-Pierrat C, Abramowski D, Wiederhold KH, Calhoun M, Jucker M, Kelly P, Staufenbiel M. Sommer B, et al. Among authors: staufenbiel m. Rev Neurosci. 2000;11(1):47-51. doi: 10.1515/revneuro.2000.11.1.47. Rev Neurosci. 2000. PMID: 10716654 Review.
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
Sturchler-Pierrat C, Abramowski D, Duke M, Wiederhold KH, Mistl C, Rothacher S, Ledermann B, Bürki K, Frey P, Paganetti PA, Waridel C, Calhoun ME, Jucker M, Probst A, Staufenbiel M, Sommer B. Sturchler-Pierrat C, et al. Among authors: staufenbiel m. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13287-92. doi: 10.1073/pnas.94.24.13287. Proc Natl Acad Sci U S A. 1997. PMID: 9371838 Free PMC article.
Co-expression of truncated and full-length tau induces severe neurotoxicity.
Ozcelik S, Sprenger F, Skachokova Z, Fraser G, Abramowski D, Clavaguera F, Probst A, Frank S, Müller M, Staufenbiel M, Goedert M, Tolnay M, Winkler DT. Ozcelik S, et al. Among authors: staufenbiel m. Mol Psychiatry. 2016 Dec;21(12):1790-1798. doi: 10.1038/mp.2015.228. Epub 2016 Feb 2. Mol Psychiatry. 2016. PMID: 26830137 Free PMC article.
Progressive age-related impairment of cognitive behavior in APP23 transgenic mice.
Kelly PH, Bondolfi L, Hunziker D, Schlecht HP, Carver K, Maguire E, Abramowski D, Wiederhold KH, Sturchler-Pierrat C, Jucker M, Bergmann R, Staufenbiel M, Sommer B. Kelly PH, et al. Among authors: staufenbiel m. Neurobiol Aging. 2003 Mar-Apr;24(2):365-78. doi: 10.1016/s0197-4580(02)00098-2. Neurobiol Aging. 2003. PMID: 12498971
Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid.
Calhoun ME, Burgermeister P, Phinney AL, Stalder M, Tolnay M, Wiederhold KH, Abramowski D, Sturchler-Pierrat C, Sommer B, Staufenbiel M, Jucker M. Calhoun ME, et al. Among authors: staufenbiel m. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):14088-93. doi: 10.1073/pnas.96.24.14088. Proc Natl Acad Sci U S A. 1999. PMID: 10570203 Free PMC article.
214 results