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A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand.
Neuropharmacology. 1996 Jun;35(6):725-34. doi: 10.1016/0028-3908(96)84644-2.
Neuropharmacology. 1996.
PMID: 8887981
Ligands for brain cholinergic channel receptors: synthesis and in vitro characterization of novel isoxazoles and isothiazoles as bioisosteric replacements for the pyridine ring in nicotine.
Garvey DS, Wasicak JT, Elliott RL, Lebold SA, Hettinger AM, Carrera GM, Lin NH, He Y, Holladay MW, Anderson DJ, et al.
Garvey DS, et al. Among authors: hettinger am.
J Med Chem. 1994 Dec 23;37(26):4455-63. doi: 10.1021/jm00052a005.
J Med Chem. 1994.
PMID: 7799396
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Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.
Abreo MA, Lin NH, Garvey DS, Gunn DE, Hettinger AM, Wasicak JT, Pavlik PA, Martin YC, Donnelly-roberts DL, Anderson DJ, Sullivan JP, Williams M, Arneric SP, Holladay MW.
Abreo MA, et al. Among authors: hettinger am.
J Med Chem. 1996 Feb 16;39(4):817-25. doi: 10.1021/jm9506884.
J Med Chem. 1996.
PMID: 8632405
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Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice.
Holladay MW, Bai H, Li Y, Lin NH, Daanen JF, Ryther KB, Wasicak JT, Kincaid JF, He Y, Hettinger AM, Huang P, Anderson DJ, Bannon AW, Buckley MJ, Campbell JE, Donnelly-Roberts DL, Gunther KL, Kim DJ, Kuntzweiler TA, Sullivan JP, Decker MW, Arneric SP.
Holladay MW, et al. Among authors: hettinger am.
Bioorg Med Chem Lett. 1998 Oct 6;8(19):2797-802. doi: 10.1016/s0960-894x(98)00504-6.
Bioorg Med Chem Lett. 1998.
PMID: 9873625
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Structure-activity studies on a novel series of cholinergic channel activators based on a heteroaryl ether framework.
Lin NH, Abreo MA, Gunn DE, Lebold SA, Lee EL, Wasicak JT, Hettinger AM, Daanen JF, Garvey DS, Campbell JE, Sullivan JP, Williams M, Arneric SP.
Lin NH, et al. Among authors: hettinger am.
Bioorg Med Chem Lett. 1999 Sep 20;9(18):2747-52. doi: 10.1016/s0960-894x(99)00462-x.
Bioorg Med Chem Lett. 1999.
PMID: 10509928
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Detection of bradykinin and bradykinin-beta(2) receptors in the porcine endometrium during the estrous cycle and early pregnancy.
Allen MR, Zhang BR, Hettinger AM, Goad DW, Malayer JR, Geisert RD.
Allen MR, et al. Among authors: hettinger am.
Biol Reprod. 2002 Mar;66(3):574-9. doi: 10.1095/biolreprod66.3.574.
Biol Reprod. 2002.
PMID: 11870060
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Presence of the acute phase protein, bikunin, in the endometrium of gilts during estrous cycle and early pregnancy.
Hettinger AM, Allen MR, Zhang BR, Goad DW, Malayer JR, Geisert RD.
Hettinger AM, et al.
Biol Reprod. 2001 Aug;65(2):507-13. doi: 10.1095/biolreprod65.2.507.
Biol Reprod. 2001.
PMID: 11466219
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