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Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects.
Chapman IM, Bach MA, Van Cauter E, Farmer M, Krupa D, Taylor AM, Schilling LM, Cole KY, Skiles EH, Pezzoli SS, Hartman ML, Veldhuis JD, Gormley GJ, Thorner MO. Chapman IM, et al. Among authors: skiles eh. J Clin Endocrinol Metab. 1996 Dec;81(12):4249-57. doi: 10.1210/jcem.81.12.8954023. J Clin Endocrinol Metab. 1996. PMID: 8954023 Clinical Trial.
Oral administration of growth hormone (GH) releasing peptide-mimetic MK-677 stimulates the GH/insulin-like growth factor-I axis in selected GH-deficient adults.
Chapman IM, Pescovitz OH, Murphy G, Treep T, Cerchio KA, Krupa D, Gertz B, Polvino WJ, Skiles EH, Pezzoli SS, Thorner MO. Chapman IM, et al. Among authors: skiles eh. J Clin Endocrinol Metab. 1997 Oct;82(10):3455-63. doi: 10.1210/jcem.82.10.4297. J Clin Endocrinol Metab. 1997. PMID: 9329386 Clinical Trial.