Kondo H - Search Results

1

Studies on selectin blockers. 4. Structure-function relationships of sulfated sialyl Lewis X hexasaccharide ceramides toward E-, P-, and L-selectin binding.

Yoshino K, Ohmoto H, Kondo N, Tsujishita H, Hiramatsu Y, Inoue Y, Kondo H. Yoshino K, et al. Among authors: kondo n, kondo h. J Med Chem. 1997 Feb 14;40(4):455-62. doi: 10.1021/jm9605290. J Med Chem. 1997. PMID: 9046335

2

Synthesis and antibacterial activity of a new series of tetracyclic pyridone carboxylic acids.

Jinbo Y, Taguchi M, Inoue Y, Kondo H, Miyasaka T, Tsujishita H, Sakamoto F, Tsukamoto G. Jinbo Y, et al. Among authors: kondo h. J Med Chem. 1993 Oct 15;36(21):3148-53. doi: 10.1021/jm00073a014. J Med Chem. 1993. PMID: 8230101

3

Studies on selectin blocker. 1. Structure-activity relationships of sialyl Lewis X analogs.

Ohmoto H, Nakamura K, Inoue T, Kondo N, Inoue Y, Yoshino K, Kondo H, Ishida H, Kiso M, Hasegawa A. Ohmoto H, et al. Among authors: kondo n, kondo h. J Med Chem. 1996 Mar 15;39(6):1339-43. doi: 10.1021/jm9506478. J Med Chem. 1996. PMID: 8632441

4

Studies on selectin blockers. 2. Novel selectin blocker as potential therapeutics for inflammatory disorders.

Wada Y, Saito T, Matsuda N, Ohmoto H, Yoshino K, Ohashi M, Kondo H, Ishida H, Kiso M, Hasegawa A. Wada Y, et al. Among authors: kondo h. J Med Chem. 1996 May 10;39(10):2055-9. doi: 10.1021/jm950877m. J Med Chem. 1996. PMID: 8642564

5

Studies on selectin blocker. 3. Investigation of the carbohydrate ligand sialyl Lewis X recognition site of P-selectin.

Hiramatsu Y, Tsujishita H, Kondo H. Hiramatsu Y, et al. Among authors: kondo h. J Med Chem. 1996 Nov 8;39(23):4547-53. doi: 10.1021/jm960134g. J Med Chem. 1996. PMID: 8917642

6

Selectin-ligand interactions revealed by molecular dynamics simulation in solution.

Tsujishita H, Hiramatsu Y, Kondo N, Ohmoto H, Kondo H, Kiso M, Hasegawa A. Tsujishita H, et al. Among authors: kondo n, kondo h. J Med Chem. 1997 Jan 31;40(3):362-9. doi: 10.1021/jm9606103. J Med Chem. 1997. PMID: 9022803

7

Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides.

Tsukida T, Hiramatsu Y, Tsujishita H, Kiyoi T, Yoshida M, Kurokawa K, Moriyama H, Ohmoto H, Wada Y, Saito T, Kondo H. Tsukida T, et al. Among authors: kondo h. J Med Chem. 1997 Oct 24;40(22):3534-41. doi: 10.1021/jm970262k. J Med Chem. 1997. PMID: 9357520

8

Synthesis of sialyl Lewis X pentasaccharide analogue for high-throughput screening of selectin blockers.

Kiyoi T, Inoue Y, Ohmoto H, Yoshida M, Kiso M, Kondo H. Kiyoi T, et al. Among authors: kondo h. Bioorg Med Chem. 1998 May;6(5):587-93. doi: 10.1016/s0968-0896(98)00003-0. Bioorg Med Chem. 1998. PMID: 9629472

9

Studies on selectin blockers. 6. Discovery of homologous fucose sugar unit necessary for E-selectin binding.

Hiramatsu Y, Moriyama H, Kiyoi T, Tsukida T, Inoue Y, Kondo H. Hiramatsu Y, et al. Among authors: kondo h. J Med Chem. 1998 Jun 18;41(13):2302-7. doi: 10.1021/jm9707481. J Med Chem. 1998. PMID: 9632363

10

Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides.

Tsukida T, Moriyama H, Kurokawa K, Achiha T, Inoue Y, Kondo H. Tsukida T, et al. Among authors: kondo h. J Med Chem. 1998 Oct 22;41(22):4279-87. doi: 10.1021/jm980267x. J Med Chem. 1998. PMID: 9784103

We have previously found that heterochiral fucodipeptides, L-Ser-D-Glu (3a) and D-Ser-L-Glu (3b), exhibited up to 20-100 times more potency than a sialyl Lewis X (sLeX, 1) and a 3'-sulfated Lewis X analogue (2) toward E-selectin binding and have also proposed, from molecular dyna …

We have previously found that heterochiral fucodipeptides, L-Ser-D-Glu (3a) and D-Ser-L-Glu (3b), exhibited up to 20-100 times more potency …

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