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1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2.
J Med Chem. 1997 May 23;40(11):1619-33. doi: 10.1021/jm970036a.
J Med Chem. 1997.
PMID: 9171872
Diarylspiro[2.4]heptenes as orally active, highly selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationships.
Huang HC, Li JJ, Garland DJ, Chamberlain TS, Reinhard EJ, Manning RE, Seibert K, Koboldt CM, Gregory SA, Anderson GD, Veenhuizen AW, Zhang Y, Perkins WE, Burton EG, Cogburn JN, Isakson PC, Reitz DB.
Huang HC, et al. Among authors: veenhuizen aw.
J Med Chem. 1996 Jan 5;39(1):253-66. doi: 10.1021/jm950664x.
J Med Chem. 1996.
PMID: 8568815
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Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
Penning TD, Talley JJ, Bertenshaw SR, Carter JS, Collins PW, Docter S, Graneto MJ, Lee LF, Malecha JW, Miyashiro JM, Rogers RS, Rogier DJ, Yu SS, AndersonGD, Burton EG, Cogburn JN, Gregory SA, Koboldt CM, Perkins WE, Seibert K, Veenhuizen AW, Zhang YY, Isakson PC.
Penning TD, et al. Among authors: veenhuizen aw.
J Med Chem. 1997 Apr 25;40(9):1347-65. doi: 10.1021/jm960803q.
J Med Chem. 1997.
PMID: 9135032
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1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
Khanna IK, Weier RM, Yu Y, Xu XD, Koszyk FJ, Collins PW, Koboldt CM, Veenhuizen AW, Perkins WE, Casler JJ, Masferrer JL, Zhang YY, Gregory SA, Seibert K, Isakson PC.
Khanna IK, et al. Among authors: veenhuizen aw.
J Med Chem. 1997 May 23;40(11):1634-47. doi: 10.1021/jm9700225.
J Med Chem. 1997.
PMID: 9171873
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Selective cyclooxygenase-2 inhibitors: heteroaryl modified 1,2-diarylimidazoles are potent, orally active antiinflammatory agents.
Khanna IK, Yu Y, Huff RM, Weier RM, Xu X, Koszyk FJ, Collins PW, Cogburn JN, Isakson PC, Koboldt CM, Masferrer JL, Perkins WE, Seibert K, Veenhuizen AW, Yuan J, Yang DC, Zhang YY.
Khanna IK, et al. Among authors: veenhuizen aw.
J Med Chem. 2000 Aug 10;43(16):3168-85. doi: 10.1021/jm0000719.
J Med Chem. 2000.
PMID: 10956225
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Characterization of a monoclonal antibody that neutralizes the activity of prostaglandin E2.
Mnich SJ, Veenhuizen AW, Monahan JB, Sheehan KC, Lynch KR, Isakson PC, Portanova JP.
Mnich SJ, et al. Among authors: veenhuizen aw.
J Immunol. 1995 Nov 1;155(9):4437-44.
J Immunol. 1995.
PMID: 7594605
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Characterization of the cytoprotective action of peroxynitrite decomposition catalysts.
Misko TP, Highkin MK, Veenhuizen AW, Manning PT, Stern MK, Currie MG, Salvemini D.
Misko TP, et al. Among authors: veenhuizen aw.
J Biol Chem. 1998 Jun 19;273(25):15646-53. doi: 10.1074/jbc.273.25.15646.
J Biol Chem. 1998.
PMID: 9624158
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