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Combination immunotherapy with vaccine and oncolytic HSV virotherapy is time dependent.
Totsch SK, Ishizuka AS, Kang KD, Gary SE, Rocco A, Fan AE, Zhou L, Valdes PA, Lee S, Li J, Peruzzotti-Jametti L, Blitz S, Garliss CM, Johnston JM, Markert JM, Lynn GM, Bernstock JD, Friedman GK. Totsch SK, et al. Among authors: lynn gm. Mol Cancer Ther. 2024 May 6. doi: 10.1158/1535-7163.MCT-23-0873. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38710101
Structural basis for self-discrimination by neoantigen-specific TCRs.
Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Finnigan JP, et al. Among authors: lynn gm. Nat Commun. 2024 Mar 8;15(1):2140. doi: 10.1038/s41467-024-46367-9. Nat Commun. 2024. PMID: 38459027 Free PMC article.
Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing.
Zumbrun EE, Garvey CB, Wells JB, Lynn GC, Van Tongeren S, Steffens JT, Wetzel KS, Gomba LM, O'Brien KA, Rossi FD, Zeng X, Lee ED, Raymond JLW, Hoffman DA, Jay AN, Brown ES, Kallgren PA, Norris SL, Cantey-Kiser J, Kudiya H, Arthur C, Blair C, Babusis D, Chu VC, Singh B, Bannister R, Porter DP, Cihlar T, Dye JM. Zumbrun EE, et al. Among authors: lynn gc. Viruses. 2023 Nov 28;15(12):2335. doi: 10.3390/v15122335. Viruses. 2023. PMID: 38140576 Free PMC article.
Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression.
Ramirez-Valdez RA, Baharom F, Khalilnezhad A, Fussell SC, Hermans DJ, Schrager AM, Tobin KKS, Lynn GM, Khalilnezhad S, Ginhoux F, Van den Eynde BJ, Leung CSK, Ishizuka AS, Seder RA. Ramirez-Valdez RA, et al. Among authors: lynn gm. Cell Rep. 2023 Jun 27;42(6):112599. doi: 10.1016/j.celrep.2023.112599. Epub 2023 Jun 7. Cell Rep. 2023. PMID: 37279110 Free PMC article.
Role of cGAS-Sting Signaling in Alzheimer's Disease.
Govindarajulu M, Ramesh S, Beasley M, Lynn G, Wallace C, Labeau S, Pathak S, Nadar R, Moore T, Dhanasekaran M. Govindarajulu M, et al. Among authors: lynn g. Int J Mol Sci. 2023 May 2;24(9):8151. doi: 10.3390/ijms24098151. Int J Mol Sci. 2023. PMID: 37175853 Free PMC article. Review.
Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs.
Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Finnigan JP, et al. Among authors: lynn gm. Res Sq [Preprint]. 2023 Jan 31:rs.3.rs-2531184. doi: 10.21203/rs.3.rs-2531184/v1. Res Sq. 2023. PMID: 36778273 Free PMC article. Updated. Preprint.
Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment.
Baharom F, Ramirez-Valdez RA, Khalilnezhad A, Khalilnezhad S, Dillon M, Hermans D, Fussell S, Tobin KKS, Dutertre CA, Lynn GM, Müller S, Ginhoux F, Ishizuka AS, Seder RA. Baharom F, et al. Among authors: lynn gm. Cell. 2022 Nov 10;185(23):4317-4332.e15. doi: 10.1016/j.cell.2022.10.006. Epub 2022 Oct 26. Cell. 2022. PMID: 36302380 Free PMC article.
87 results