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Novel nonpeptide CCK-B antagonists: design and development of quinazolinone derivatives as potent, selective, and orally active CCK-B antagonists.
J Med Chem. 1998 Mar 26;41(7):1042-9. doi: 10.1021/jm970373j.
J Med Chem. 1998.
PMID: 9544204
Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.
Trivedi BK, Padia JK, Holmes A, Rose S, Wright DS, Hinton JP, Pritchard MC, Eden JM, Kneen C, Webdale L, Suman-Chauhan N, Boden P, Singh L, Field MJ, Hill D.
Trivedi BK, et al. Among authors: padia jk.
J Med Chem. 1998 Jan 1;41(1):38-45. doi: 10.1021/jm970065l.
J Med Chem. 1998.
PMID: 9438020
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Inhibitors of lipoprotein(a) assembly.
Sexton KE, Lee HT, Massa M, Padia J, Patt WC, Liao P, Pontrello JK, Roth BD, Spahr MA, Ramharack R.
Sexton KE, et al. Among authors: padia j.
Bioorg Med Chem. 2003 Nov 3;11(22):4827-45. doi: 10.1016/j.bmc.2002.04.001.
Bioorg Med Chem. 2003.
PMID: 14556799
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Bioisosterism in drug design: identification of and structure-activity relationships in a series of glycine anilide ACAT inhibitors.
Roark WH, Padia J, Bolton GL, Blankley CJ, Essenburg AD, Stanfield RL, Bousley RF, Krause BR, Roth BD.
Roark WH, et al.
Bioorg Med Chem. 1995 Jan;3(1):29-39. doi: 10.1016/0968-0896(94)00144-r.
Bioorg Med Chem. 1995.
PMID: 8612044
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Design, Synthesis, and Biological Evaluation of a Series of Anthracene-9,10-dione Dioxime β-Catenin Pathway Inhibitors.
Soldi R, Horrigan SK, Cholody MW, Padia J, Sorna V, Bearss J, Gilcrease G, Bhalla K, Verma A, Vankayalapati H, Sharma S.
Soldi R, et al.
J Med Chem. 2015 Aug 13;58(15):5854-62. doi: 10.1021/acs.jmedchem.5b00460. Epub 2015 Jul 31.
J Med Chem. 2015.
PMID: 26182238
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Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia-adaptation by AV65--a novel Wnt/β-catenin signaling inhibitor.
Nagao R, Ashihara E, Kimura S, Strovel JW, Yao H, Takeuchi M, Tanaka R, Hayashi Y, Hirai H, Padia J, Strand K, Maekawa T.
Nagao R, et al.
Cancer Lett. 2011 Dec 15;312(1):91-100. doi: 10.1016/j.canlet.2011.08.002. Epub 2011 Aug 17.
Cancer Lett. 2011.
PMID: 21906872
Free article.
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AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model.
Yao H, Ashihara E, Strovel JW, Nakagawa Y, Kuroda J, Nagao R, Tanaka R, Yokota A, Takeuchi M, Hayashi Y, Shimazaki C, Taniwaki M, Strand K, Padia J, Hirai H, Kimura S, Maekawa T.
Yao H, et al.
Blood Cancer J. 2011 Nov;1(11):e43. doi: 10.1038/bcj.2011.41. Epub 2011 Nov 4.
Blood Cancer J. 2011.
PMID: 22829079
Free PMC article.
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Discovery and Preclinical Development of Antigiardiasis Fumagillol Derivatives.
Padia J, Kulakova L, Galkin A, Herzberg O.
Padia J, et al.
Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00582-20. doi: 10.1128/AAC.00582-20. Print 2020 Sep 21.
Antimicrob Agents Chemother. 2020.
PMID: 32778548
Free PMC article.
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