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Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated state.
Chen D, Fucini RV, Olson AL, Hemmings BA, Pessin JE. Chen D, et al. Mol Cell Biol. 1999 Jul;19(7):4684-94. doi: 10.1128/MCB.19.7.4684. Mol Cell Biol. 1999. PMID: 10373517 Free PMC article.
We have previously reported that insulin and osmotic shock stimulate an increase in glucose transport activity and translocation of the insulin-responsive glucose transporter isoform GLUT4 to the plasma membrane through distinct pathways in 3T3L1 adipocytes (D. Chen …
We have previously reported that insulin and osmotic shock stimulate an increase in glucose transport activity and translocation of the insu …
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