Guzzi M - Search Results

1

GR231118 (1229U91) and other analogues of the C-terminus of neuropeptide Y are potent neuropeptide Y Y1 receptor antagonists and neuropeptide Y Y4 receptor agonists.

Parker EM, Babij CK, Balasubramaniam A, Burrier RE, Guzzi M, Hamud F, Mukhopadhyay G, Rudinski MS, Tao Z, Tice M, Xia L, Mullins DE, Salisbury BG. Parker EM, et al. Among authors: guzzi m. Eur J Pharmacol. 1998 May 15;349(1):97-105. doi: 10.1016/s0014-2999(98)00171-x. Eur J Pharmacol. 1998. PMID: 9669502

2

Identification and characterization of pseudoirreversible nonpeptide antagonists of the neuropeptide Y Y5 receptor and development of a novel Y5-selective radioligand.

Mullins D, Adham N, Hesk D, Wu Y, Kelly J, Huang Y, Guzzi M, Zhang X, McCombie S, Stamford A, Parker E. Mullins D, et al. Among authors: guzzi m. Eur J Pharmacol. 2008 Dec 28;601(1-3):1-7. doi: 10.1016/j.ejphar.2008.10.021. Epub 2008 Oct 18. Eur J Pharmacol. 2008. PMID: 18976648

3

[D-Trp(34)] neuropeptide Y is a potent and selective neuropeptide Y Y(5) receptor agonist with dramatic effects on food intake.

Parker EM, Balasubramaniam A, Guzzi M, Mullins DE, Salisbury BG, Sheriff S, Witten MB, Hwa JJ. Parker EM, et al. Among authors: guzzi m. Peptides. 2000 Mar;21(3):393-9. doi: 10.1016/s0196-9781(00)00156-x. Peptides. 2000. PMID: 10793222

4

Pharmacological characterization of the cloned neuropeptide Y y(6) receptor.

Mullins DE, Guzzi M, Xia L, Parker EM. Mullins DE, et al. Among authors: guzzi m. Eur J Pharmacol. 2000 Apr 28;395(2):87-93. doi: 10.1016/s0014-2999(00)00255-7. Eur J Pharmacol. 2000. PMID: 10794812

5

Identification of potent and selective neuropeptide Y Y(1) receptor agonists with orexigenic activity in vivo.

Mullins D, Kirby D, Hwa J, Guzzi M, Rivier J, Parker E. Mullins D, et al. Among authors: guzzi m. Mol Pharmacol. 2001 Sep;60(3):534-40. Mol Pharmacol. 2001. PMID: 11502885

6

Genomic organization and functional characterization of the mouse GalR1 galanin receptor.

Wang S, He C, Maguire MT, Clemmons AL, Burrier RE, Guzzi MF, Strader CD, Parker EM, Bayne ML. Wang S, et al. Among authors: guzzi mf. FEBS Lett. 1997 Jul 14;411(2-3):225-30. doi: 10.1016/s0014-5793(97)00695-9. FEBS Lett. 1997. PMID: 9271210 Free article.

7

Comparison of the V1b antagonist, SSR149415, and the CRF1 antagonist, CP-154,526, in rodent models of anxiety and depression.

Hodgson RA, Higgins GA, Guthrie DH, Lu SX, Pond AJ, Mullins DE, Guzzi MF, Parker EM, Varty GB. Hodgson RA, et al. Among authors: guzzi mf. Pharmacol Biochem Behav. 2007 Mar;86(3):431-40. doi: 10.1016/j.pbb.2006.12.021. Epub 2007 Jan 9. Pharmacol Biochem Behav. 2007. PMID: 17291571

8

Highly selective and potent neuropeptide Y (NPY) Y1 receptor antagonists based on [Pro(30), Tyr(32), Leu(34)]NPY(28-36)-NH2 (BW1911U90).

Balasubramaniam A, Dhawan VC, Mullins DE, Chance WT, Sheriff S, Guzzi M, Prabhakaran M, Parker EM. Balasubramaniam A, et al. Among authors: guzzi m. J Med Chem. 2001 May 10;44(10):1479-82. doi: 10.1021/jm010031k. J Med Chem. 2001. PMID: 11334558 No abstract available.

9

Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY(32-36): development of an anorectic Y4 receptor selective agonist with picomolar affinity.

Balasubramaniam A, Mullins DE, Lin S, Zhai W, Tao Z, Dhawan VC, Guzzi M, Knittel JJ, Slack K, Herzog H, Parker EM. Balasubramaniam A, et al. Among authors: guzzi m. J Med Chem. 2006 Apr 20;49(8):2661-5. doi: 10.1021/jm050907d. J Med Chem. 2006. PMID: 16610810

10

Discovery of novel orally active ureido NPY Y5 receptor antagonists.

Li G, Stamford AW, Huang Y, Cheng KC, Cook J, Farley C, Gao J, Ghibaudi L, Greenlee WJ, Guzzi M, van Heek M, Hwa JJ, Kelly J, Mullins D, Parker EM, Wainhaus S, Zhang X. Li G, et al. Among authors: guzzi m. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1146-50. doi: 10.1016/j.bmcl.2007.11.132. Epub 2007 Dec 5. Bioorg Med Chem Lett. 2008. PMID: 18160282

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