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P2-proline-derived inhibitors of calpain I.
Tripathy R, Gu ZQ, Dunn D, Senadhi SE, Ator MA, Chatterjee S. Tripathy R, et al. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2647-52. doi: 10.1016/s0960-894x(98)00470-3. Bioorg Med Chem Lett. 1998. PMID: 9873596
Strategies to mitigate the bioactivation of 2-anilino-7-aryl-pyrrolo[2,1-f][1,2,4]triazines: identification of orally bioavailable, efficacious ALK inhibitors.
Mesaros EF, Thieu TV, Wells GJ, Zificsak CA, Wagner JC, Breslin HJ, Tripathy R, Diebold JL, McHugh RJ, Wohler AT, Quail MR, Wan W, Lu L, Huang Z, Albom MS, Angeles TS, Wells-Knecht KJ, Aimone LD, Cheng M, Ator MA, Ott GR, Dorsey BD. Mesaros EF, et al. Among authors: tripathy r. J Med Chem. 2012 Jan 12;55(1):115-25. doi: 10.1021/jm2010767. Epub 2011 Dec 29. J Med Chem. 2012. PMID: 22141319
D-amino acid containing, high-affinity inhibitors of recombinant human calpain I.
Chatterjee S, Gu ZQ, Dunn D, Tao M, Josef K, Tripathy R, Bihovsky R, Senadhi SE, O'Kane TM, McKenna BA, Mallya S, Ator MA, Bozyczko-Coyne D, Siman R, Mallamo JP. Chatterjee S, et al. Among authors: tripathy r. J Med Chem. 1998 Jul 16;41(15):2663-6. doi: 10.1021/jm980035y. J Med Chem. 1998. PMID: 9667954 No abstract available.
Discovery of a potent inhibitor of anaplastic lymphoma kinase with in vivo antitumor activity.
Ott GR, Tripathy R, Cheng M, McHugh R, Anzalone AV, Underiner TL, Curry MA, Quail MR, Lu L, Wan W, Angeles TS, Albom MS, Aimone LD, Ator MA, Ruggeri BA, Dorsey BD. Ott GR, et al. Among authors: tripathy r. ACS Med Chem Lett. 2010 Sep 1;1(9):493-8. doi: 10.1021/ml100158s. eCollection 2010 Dec 9. ACS Med Chem Lett. 2010. PMID: 24900237 Free PMC article.
Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors.
Weinberg LR, Albom MS, Angeles TS, Husten J, Lisko JG, McHugh RJ, Milkiewicz KL, Murthy S, Ott GR, Theroff JP, Tripathy R, Underiner TL, Zificsak CA, Dorsey BD. Weinberg LR, et al. Among authors: tripathy r. Bioorg Med Chem Lett. 2011 Jan 1;21(1):164-7. doi: 10.1016/j.bmcl.2010.11.045. Epub 2010 Nov 11. Bioorg Med Chem Lett. 2011. PMID: 21123062
134 results