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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1914 1
1929 2
1930 4
1931 2
1932 2
1933 4
1934 5
1935 6
1936 9
1937 8
1938 11
1939 7
1940 5
1941 6
1943 4
1944 6
1945 31
1946 79
1947 90
1948 111
1949 83
1950 129
1951 132
1952 155
1953 171
1954 146
1955 168
1956 164
1957 167
1958 160
1959 169
1960 192
1961 190
1962 228
1963 478
1964 604
1965 510
1966 559
1967 709
1968 760
1969 855
1970 869
1971 962
1972 978
1973 1007
1974 1088
1975 1101
1976 1129
1977 1209
1978 1135
1979 1154
1980 1292
1981 1234
1982 1333
1983 1443
1984 1439
1985 1475
1986 1611
1987 1615
1988 1673
1989 1879
1990 1933
1991 1948
1992 2008
1993 2196
1994 2111
1995 2089
1996 2091
1997 2164
1998 2150
1999 2047
2000 2253
2001 2086
2002 2104
2003 2136
2004 2164
2005 2260
2006 2461
2007 2383
2008 2389
2009 2341
2010 2368
2011 2306
2012 2391
2013 2544
2014 2381
2015 2438
2016 2363
2017 2353
2018 2315
2019 2097
2020 2320
2021 2354
2022 2071
2023 1875
2024 1058
2025 1

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102,993 results

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Page 1
Dequalinium chloride is an antagonists of alpha7 nicotinic acetylcholine receptors.
Belanger-Coast MG, Zhang M, Bugay V, Gutierrez RA, Gregory SR, Yu W, Brenner R. Belanger-Coast MG, et al. Eur J Pharmacol. 2022 Jun 15;925:175000. doi: 10.1016/j.ejphar.2022.175000. Epub 2022 May 4. Eur J Pharmacol. 2022. PMID: 35525312
Here we investigated dequalinium chloride as an antagonist to alpha7 nicotinic acetylcholine receptors. ...Using calcium dye fluorescence plate reader measurements, we find dequalinium chloride is an antagonist of alpha7 nicotinic acetylcholine recepto …
Here we investigated dequalinium chloride as an antagonist to alpha7 nicotinic acetylcholine receptors. ...Using calcium dye f …
Early postdenervation depolarization is controlled by acetylcholine and glutamate via nitric oxide regulation of the chloride transporter.
Vyskocil F. Vyskocil F. Neurochem Res. 2003 Apr;28(3-4):575-85. doi: 10.1023/a:1022833709448. Neurochem Res. 2003. PMID: 12675147 Review.
Resting non-quantal acetylcholine (ACh) and probably glutamate (Glu) release from nerve endings activates M1- and NMDA receptor-mediated Ca2+ entry into the sarcoplasm with following activation of NOS and production of NO. ...
Resting non-quantal acetylcholine (ACh) and probably glutamate (Glu) release from nerve endings activates M1- and NMDA receptor-media …
Acetylcholine-activated chloride current in the T-84 colonic cell line.
Cliff WH, Duffey ME, Packianathan N. Cliff WH, et al. Pflugers Arch. 1998 Jun;436(1):90-4. doi: 10.1007/s004240050608. Pflugers Arch. 1998. PMID: 9560451
The stimulation of epithelial chloride secretion by hormones and neurotransmitters involves the activation of apical membrane chloride channels. The regulation of chloride current by acetylcholine in the T-84 colonic cell line was investigated using si …
The stimulation of epithelial chloride secretion by hormones and neurotransmitters involves the activation of apical membrane chlo …
Acetylcholine chloride as a potential source of variability in the study of cutaneous vascular function in man.
Sauvet F, Mahé G, Chennaoui M, Langrume C, Vasseur M, Abraham P, Leftheriotis G. Sauvet F, et al. Microvasc Res. 2011 Sep;82(2):190-7. doi: 10.1016/j.mvr.2011.05.001. Epub 2011 May 12. Microvasc Res. 2011. PMID: 21601579
INTRODUCTION: Laser-Doppler flowmetry (LDF) coupled with acetylcholine chloride (ACh) iontophoresis is increasingly recognized as a reliable non-invasive method to study the endothelial function. ...These problems may be partially overcome by using methacholine c …
INTRODUCTION: Laser-Doppler flowmetry (LDF) coupled with acetylcholine chloride (ACh) iontophoresis is increasingly recognized …
The Validation of Nematode-Specific Acetylcholine-Gated Chloride Channels as Potential Anthelmintic Drug Targets.
Wever CM, Farrington D, Dent JA. Wever CM, et al. PLoS One. 2015 Sep 22;10(9):e0138804. doi: 10.1371/journal.pone.0138804. eCollection 2015. PLoS One. 2015. PMID: 26393923 Free PMC article.
We validated five members of the nematode-specific family of acetylcholine-gated chloride channels as targets of agonists with anthelmintic properties by ectopically expressing an ivermectin-gated chloride channel, AVR-15, in tissues that endogenously express …
We validated five members of the nematode-specific family of acetylcholine-gated chloride channels as targets of agonists with …
Advances in our understanding of nematode ion channels as potential anthelmintic targets.
Choudhary S, Kashyap SS, Martin RJ, Robertson AP. Choudhary S, et al. Int J Parasitol Drugs Drug Resist. 2022 Apr;18:52-86. doi: 10.1016/j.ijpddr.2021.12.001. Epub 2021 Dec 25. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35149380 Free PMC article. Review.
We review cys-loop ligand gated ion channels (LGICs), including nicotinic acetylcholine receptors (nAChRs), acetylcholine-chloride gated ion channels (ACCs), glutamate-gated chloride channels (GluCls), and GABA (gamma-aminobutyric acid) receptors, and …
We review cys-loop ligand gated ion channels (LGICs), including nicotinic acetylcholine receptors (nAChRs), acetylcholine-c …
Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus.
Habibi SA, Callanan M, Forrester SG. Habibi SA, et al. Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):518-525. doi: 10.1016/j.ijpddr.2018.09.004. Epub 2018 Sep 22. Int J Parasitol Drugs Drug Resist. 2018. PMID: 30266440 Free PMC article.
Nematode cys-loop ligand-gated ion channels (LGICs) have been shown to be attractive targets for the development of novel anti-parasitic drugs. The ACC-1 family of receptors are a unique group of acetylcholine-gated chloride channels present only in invertebrates, a …
Nematode cys-loop ligand-gated ion channels (LGICs) have been shown to be attractive targets for the development of novel anti-parasitic dru …
Inhibition of p53 Mutant Peptide Aggregation In Vitro by Cationic Osmolyte Acetylcholine Chloride.
Chen Z, Kanapathipillai M. Chen Z, et al. Protein Pept Lett. 2017;24(4):353-357. doi: 10.2174/0929866524666170123142858. Protein Pept Lett. 2017. PMID: 28117010
Here in this study we focus on the inhibitory effects of cationic osmolyte molecules acetylcholine chloride, and choline on an aggregation prone 10 amino acid p53 mutant peptide WRPILTIITL, and the corresponding wildtype peptide RRPILTIITL in vitro. The characteriza …
Here in this study we focus on the inhibitory effects of cationic osmolyte molecules acetylcholine chloride, and choline on an …
Comparison of intraocular acetylcholine and carbachol.
Yee RW, Edelhauser HF. Yee RW, et al. J Cataract Refract Surg. 1986 Jan;12(1):18-22. doi: 10.1016/s0886-3350(86)80049-9. J Cataract Refract Surg. 1986. PMID: 3958945
Commercially available 1% acetylcholine chloride and 0.01% carbachol chloride, which are commonly used as miotics in intraocular surgery, have recently been reformulated. ...This study showed that 0.01% carbachol chloride was less toxic to the corneal …
Commercially available 1% acetylcholine chloride and 0.01% carbachol chloride, which are commonly used as miotics in in …
102,993 results
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