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Comparison of Efficacy and Safety of Azilsartan and Amlodipine Combination Versus Telmisartan and Amlodipine Combination in Hypertensive Patients: A Non-inferiority Trial.
Dash A, Meher BR, Padhy BM, Mohanty RR, Tripathy A. Dash A, et al. Cureus. 2023 Mar 7;15(3):e35865. doi: 10.7759/cureus.35865. eCollection 2023 Mar. Cureus. 2023. PMID: 37033509 Free PMC article.
The objective of this study was to compare the efficacy and safety of the azilsartan and amlodipine combination versus the telmisartan and amlodipine combination in hypertensive patients. ...The most commonly reported adverse effect in both grou …
The objective of this study was to compare the efficacy and safety of the azilsartan and amlodipine combination versus …
Azilsartan, aliskiren, and combination antihypertensives utilizing renin-angiotensin-aldosterone system antagonists.
Lanier G, Sankholkar K, Aronow WS. Lanier G, et al. Am J Ther. 2014 Sep-Oct;21(5):419-35. doi: 10.1097/MJT.0b013e31824a0ed7. Am J Ther. 2014. PMID: 22975662 Review.
Seven of these combine 2 drugs together in a single pill: Edarbyclor (azilsartan/chlorthalidone), Exforge (amlodipine/valsartan), Azor (olmesartan/amlodipine), Twynsta (amlodipine/telmisartan), Tekturna HCT [aliskiren/hydrochlorothiazide (HCTZ)] …
Seven of these combine 2 drugs together in a single pill: Edarbyclor (azilsartan/chlorthalidone), Exforge (amlodipine/v …
Azilsartan medoxomil for the treatment of hypertension.
Vasiliou S. Vasiliou S. Drugs Today (Barc). 2011 Sep;47(9):647-51. doi: 10.1358/dot.2011.47.9.1688573. Drugs Today (Barc). 2011. PMID: 21971539 Review.
The agent has been evaluated as monotherapy and in combination with amlodipine or chlorthalidone in phase III trials in patients with essential hypertension. In 2011, azilsartan medoxomil was approved in the U.S. for the treatment of hypertension....
The agent has been evaluated as monotherapy and in combination with amlodipine or chlorthalidone in phase III trials in patien …
Azilsartan medoxomil in the management of hypertension: an evidence-based review of its place in therapy.
Angeloni E. Angeloni E. Core Evid. 2016 Apr 5;11:1-10. doi: 10.2147/CE.S81776. eCollection 2016. Core Evid. 2016. PMID: 27103882 Free PMC article. Review.
BACKGROUND: Azilsartan (AZI) is a relatively new angiotensin receptor blocker available for the treatment of any stage of hypertension, which was eventually given in combination with chlorthalidone (CLT). ...CONCLUSION: Azilsartan is a safe and effective trea …
BACKGROUND: Azilsartan (AZI) is a relatively new angiotensin receptor blocker available for the treatment of any stage of hypertensio …
Effects of combining azilsartan medoxomil with amlodipine in patients with stage 2 hypertension.
Weber MA, White WB, Sica D, Bakris GL, Cao C, Roberts A, Kupfer S. Weber MA, et al. Blood Press Monit. 2014 Apr;19(2):90-7. doi: 10.1097/MBP.0000000000000027. Blood Press Monit. 2014. PMID: 24445723 Free PMC article. Clinical Trial.
OBJECTIVE: The aim of the study was to measure the effects on blood pressure (BP) of the angiotensin receptor blocker azilsartan medoxomil, in 40 and 80 mg doses, combined with 5 mg of the calcium channel blocker amlodipine and to compare these effects with p …
OBJECTIVE: The aim of the study was to measure the effects on blood pressure (BP) of the angiotensin receptor blocker azilsartan medo …
A phase III, open-label, multicenter study to evaluate the safety and efficacy of long-term triple combination therapy with azilsartan, amlodipine, and hydrochlorothiazide in patients with essential hypertension.
Rakugi H, Shimizu K, Nishiyama Y, Sano Y, Umeda Y. Rakugi H, et al. Blood Press. 2018 Jun;27(3):125-133. doi: 10.1080/08037051.2017.1412797. Epub 2017 Dec 13. Blood Press. 2018. PMID: 29235365 Clinical Trial.
This study aimed to evaluate the long-term safety and efficacy of a triple combination therapy with 20 mg azilsartan (AZL), 5 mg amlodipine (AML) and 12.5 mg hydrochlorothiazide (HCTZ). ...Patients with inadequate BP control despite AZL/AML therapy (n = 341) …
This study aimed to evaluate the long-term safety and efficacy of a triple combination therapy with 20 mg azilsartan (AZL), 5 …
Evaluation of the efficacy and tolerability of fixed-dose combination therapy of azilsartan and amlodipine besylate in Japanese patients with grade I to II essential hypertension.
Rakugi H, Nakata E, Sasaki E, Kagawa T. Rakugi H, et al. Clin Ther. 2014 May;36(5):711-21. doi: 10.1016/j.clinthera.2014.03.009. Epub 2014 Apr 16. Clin Ther. 2014. PMID: 24742498 Clinical Trial.
BACKGROUND: Guidelines for the management of hypertension recommend using drugs with different mechanisms of action in antihypertensive regimens that include simple single-pill fixed-dose combination (FDC) products. OBJECTIVE: The objective of this study was to compare the …
BACKGROUND: Guidelines for the management of hypertension recommend using drugs with different mechanisms of action in antihypertensive regi …
Effects of triple combination therapy with azilsartan/amlodipine/hydrochlorothiazide on office/home blood pressure: a randomized-controlled trial in Japanese essential hypertensive patients.
Rakugi H, Shimizu K, Sano Y, Nishiyama Y, Kinugawa Y, Terashio S. Rakugi H, et al. Blood Press Monit. 2018 Apr;23(2):91-102. doi: 10.1097/MBP.0000000000000308. Blood Press Monit. 2018. PMID: 29239867 Clinical Trial.
OBJECTIVE: The efficacy and safety of triple therapy with azilsartan (AZI), amlodipine besylate (AML), and hydrochlorothiazide (HCTZ) compared with dual therapy with AZI/AML or HCTZ monotherapy were evaluated in Japanese essential hypertensive patients in a double-b …
OBJECTIVE: The efficacy and safety of triple therapy with azilsartan (AZI), amlodipine besylate (AML), and hydrochlorothiazide …