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Effect of IL-17A blockade with secukinumab in autoimmune diseases.
Patel DD, Lee DM, Kolbinger F, Antoni C. Patel DD, et al. Ann Rheum Dis. 2013 Apr;72 Suppl 2:ii116-23. doi: 10.1136/annrheumdis-2012-202371. Epub 2012 Dec 19. Ann Rheum Dis. 2013. PMID: 23253932 Review.
Genetic studies and correlative expression data in diseased tissues have pointed to the role of interleukin (IL)-17 and Th17 cells in the pathogenesis of autoimmune disorders such as psoriasis, inflammatory bowel disease and seronegative spondyloarthropathies. ...Early cli …
Genetic studies and correlative expression data in diseased tissues have pointed to the role of interleukin (IL)-17 and Th17 cells in …
Therapeutic strategies in psoriasis patients with psoriatic arthritis: focus on new agents.
Gan EY, Chong WS, Tey HL. Gan EY, et al. BioDrugs. 2013 Aug;27(4):359-73. doi: 10.1007/s40259-013-0025-6. BioDrugs. 2013. PMID: 23580094 Review.
Newer drugs in the treatment armamentarium that have shown efficacy for both psoriasis and psoriatic arthritis consist of the anti-IL-17 agent, secukinumab, and a phosphodiesterase-4 inhibitor, apremilast. The other anti-IL-17 agents, ixekizumab and brodalumab, as well as …
Newer drugs in the treatment armamentarium that have shown efficacy for both psoriasis and psoriatic arthritis consist of the anti-IL-17 age …