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Crystal chemistry of the antibiotic doripenem.
Colombo V, Masciocchi N, Palmisano G. Colombo V, et al. J Pharm Sci. 2014 Nov;103(11):3641-3647. doi: 10.1002/jps.24166. Epub 2014 Sep 17. J Pharm Sci. 2014. PMID: 25231384
Doripenem, an ultrabroad spectrum-injectable antibiotic belonging to the wide class of carbapenem beta-lactams, is commonly marketed as powders of a pure monohydrate phase. Here, we have selectively prepared another hydrated phase (a dihydrate) and determined the cr …
Doripenem, an ultrabroad spectrum-injectable antibiotic belonging to the wide class of carbapenem beta-lactams, is commonly marketed …
In vitro models to detect in vivo bile acid changes induced by antibiotics.
Zhang N, Wang J, Bakker W, Zheng W, Baccaro M, Murali A, van Ravenzwaay B, Rietjens IMCM. Zhang N, et al. Arch Toxicol. 2022 Dec;96(12):3291-3303. doi: 10.1007/s00204-022-03373-4. Epub 2022 Sep 8. Arch Toxicol. 2022. PMID: 36074177 Free PMC article.
In this study, two in vitro models were applied to further elucidate the mode of action underlying reported in vivo bile acid changes induced by antibiotics (colistin sulfate, tobramycin, meropenem trihydrate, and doripenem hydrate). 16S rRNA analysis of rat fecal s …
In this study, two in vitro models were applied to further elucidate the mode of action underlying reported in vivo bile acid changes induce …
Gateways to clinical trials.
Tomillero A, Moral MA. Tomillero A, et al. Methods Find Exp Clin Pharmacol. 2009 Jul-Aug;31(6):397-417. Methods Find Exp Clin Pharmacol. 2009. PMID: 19798455
[90Y-DOTA-Tyr3]octreotate, Abatacept, ABT-888, ACE-011, Adefovir dipivoxil, Alosetron hydrochloride, Aminolevulinic acid methyl ester, Amlodipine, Apaziquone, Aripiprazole, AS-101, Atomoxetine hydrochloride, Atrasentan, Azacitidine; Bevacizumab, Biphasic insulin aspart, Bortezomi …
[90Y-DOTA-Tyr3]octreotate, Abatacept, ABT-888, ACE-011, Adefovir dipivoxil, Alosetron hydrochloride, Aminolevulinic acid methyl ester, Amlod …
[Pubic Bone Osteomyelitis in Patient with Prostate Cancer after Robot-Assisted Laparoscopic Prostatectomy; A Case Report].
Fukui S, Iemura Y, Matsumura Y, Kagebayashi Y, Samma S. Fukui S, et al. Hinyokika Kiyo. 2019 Jan;65(1):23-27. doi: 10.14989/ActaUrolJap_65_1_23. Hinyokika Kiyo. 2019. PMID: 30831674 Free article. Japanese.
A pelvic MRI revealed inflammation of the pubic area, and pubic bone osteomyelitis was suspected. He was admitted and administered doripenem hydrate (DRPM) intravenously for 3 weeks. The symnptoms of gait disturbance, pain at the bilateral inner thigh, and lower abd …
A pelvic MRI revealed inflammation of the pubic area, and pubic bone osteomyelitis was suspected. He was admitted and administered doripe …
[A case of probable catastrophic antiphospholipid syndrome with multi-organ failure presenting as a transient increase of antiphospholipid antibody levels].
Sato R, Sato H, Nishiwaki A, Yokoe I, Tsuruta S, Haraoka H. Sato R, et al. Nihon Rinsho Meneki Gakkai Kaishi. 2014;37(3):183-8. doi: 10.2177/jsci.37.183. Nihon Rinsho Meneki Gakkai Kaishi. 2014. PMID: 24974932 Free article. Japanese.
Therefore, the patient was placed on a respirator and was administered ciprofloxacin, doripenem hydrate, thrombomodulin, antithrombin III, and methylprednisolone pulse therapy. ...
Therefore, the patient was placed on a respirator and was administered ciprofloxacin, doripenem hydrate, thrombomodulin, antit …