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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1993 1
1994 2
1995 4
1996 4
1997 8
1998 9
2000 3
2001 3
2002 16
2003 35
2004 80
2005 83
2006 94
2007 127
2008 136
2009 131
2010 150
2011 153
2012 127
2013 135
2014 117
2015 107
2016 100
2017 95
2018 92
2019 104
2020 87
2021 98
2022 118
2023 94
2024 35

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2,055 results

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Page 1
Antidepressant duloxetine hydrochloride protects against ovariectomy-induced bone loss in mice by inhibiting osteoclast differentiation.
Zhou W, Zhou W, Bi Y, Zhou Z, Zhou Z, Chen S, Xie G, Lian Z, Yuan G, Yao G. Zhou W, et al. Biomed Pharmacother. 2023 Dec;168:115810. doi: 10.1016/j.biopha.2023.115810. Epub 2023 Oct 30. Biomed Pharmacother. 2023. PMID: 37913736 Free article.
METHODS: This study investigates the independent effect of the antidepressant duloxetine hydrochloride (DH) on ovariectomy-induced bone loss in mice. ...
METHODS: This study investigates the independent effect of the antidepressant duloxetine hydrochloride (DH) on ovariectomy-ind …
Fibromyalgia: Diagnosis and Management.
Winslow BT, Vandal C, Dang L. Winslow BT, et al. Am Fam Physician. 2023 Feb;107(2):137-144. Am Fam Physician. 2023. PMID: 36791450
Patient education, exercise, and cognitive behavior therapy can improve pain and function. Duloxetine, milnacipran, pregabalin, and amitriptyline are potentially effective medications for fibromyalgia. ...
Patient education, exercise, and cognitive behavior therapy can improve pain and function. Duloxetine, milnacipran, pregabalin, and a …
Duloxetine for fibromyalgia syndrome: a systematic review and meta-analysis.
Migliorini F, Maffulli N, Eschweiler J, Baroncini A, Bell A, Colarossi G. Migliorini F, et al. J Orthop Surg Res. 2023 Jul 17;18(1):504. doi: 10.1186/s13018-023-03995-z. J Orthop Surg Res. 2023. PMID: 37461044 Free PMC article.
INTRODUCTION: The optimal dose of duloxetine in the management of fibromyalgia remains still controversial. ...CONCLUSIONS: Duloxetine could help in improving symptoms of fibromyalgia. The dose of duloxetine should be customised according to individual patien …
INTRODUCTION: The optimal dose of duloxetine in the management of fibromyalgia remains still controversial. ...CONCLUSIONS: Duloxe …
Management of diabetic neuropathy.
Cernea S, Raz I. Cernea S, et al. Metabolism. 2021 Oct;123:154867. doi: 10.1016/j.metabol.2021.154867. Epub 2021 Aug 17. Metabolism. 2021. PMID: 34411554 Review.
Comparative efficacy of amitriptyline, duloxetine and pregabalin for treating fibromyalgia in adults: an overview with network meta-analysis.
Alberti FF, Becker MW, Blatt CR, Ziegelmann PK, da Silva Dal Pizzol T, Pilger D. Alberti FF, et al. Clin Rheumatol. 2022 Jul;41(7):1965-1978. doi: 10.1007/s10067-022-06129-8. Epub 2022 Mar 26. Clin Rheumatol. 2022. PMID: 35347488 Review.
Our aim is to identify and compare the efficacy of amitriptyline (AMT), duloxetine (DLX), and pregabalin (PGB) for reducing pain intensity by 30% (R30%) and 50% (R50%) in adult patients with fibromyalgia. ...
Our aim is to identify and compare the efficacy of amitriptyline (AMT), duloxetine (DLX), and pregabalin (PGB) for reducing pain inte …
Comparing duloxetine and pregabalin for treatment of pain and depression in women with fibromyalgia: an open-label randomized clinical trial.
Bidari A, Moazen-Zadeh E, Ghavidel-Parsa B, Rahmani S, Hosseini S, Hassankhani A. Bidari A, et al. Daru. 2019 Jun;27(1):149-158. doi: 10.1007/s40199-019-00257-4. Epub 2019 Mar 14. Daru. 2019. PMID: 30877484 Free PMC article. Clinical Trial.
BACKGROUND: Duloxetine and pregabalin are among the most widely used medications in the treatment of patients with fibromyalgia syndrome (FM). ...Drop out rate and cumulative incidence of nausea was significantly higher in the duloxetine arm compared to the pregabal …
BACKGROUND: Duloxetine and pregabalin are among the most widely used medications in the treatment of patients with fibromyalgia syndr …
Pharmacological and Nonpharmacological Treatments for Painful Diabetic Peripheral Neuropathy.
Jang HN, Oh TJ. Jang HN, et al. Diabetes Metab J. 2023 Nov;47(6):743-756. doi: 10.4093/dmj.2023.0018. Epub 2023 Sep 6. Diabetes Metab J. 2023. PMID: 37670573 Free PMC article. Review.
Food and Drug Administration (FDA) has approved pregabalin, duloxetine, tapentadol, and the 8% capsaicin patch as drugs for the treatment of painful DPN. ...
Food and Drug Administration (FDA) has approved pregabalin, duloxetine, tapentadol, and the 8% capsaicin patch as drugs for the treat …
Bioaccumulation of therapeutic drugs by human gut bacteria.
Klünemann M, Andrejev S, Blasche S, Mateus A, Phapale P, Devendran S, Vappiani J, Simon B, Scott TA, Kafkia E, Konstantinidis D, Zirngibl K, Mastrorilli E, Banzhaf M, Mackmull MT, Hövelmann F, Nesme L, Brochado AR, Maier L, Bock T, Periwal V, Kumar M, Kim Y, Tramontano M, Schultz C, Beck M, Hennig J, Zimmermann M, Sévin DC, Cabreiro F, Savitski MM, Bork P, Typas A, Patil KR. Klünemann M, et al. Nature. 2021 Sep;597(7877):533-538. doi: 10.1038/s41586-021-03891-8. Epub 2021 Sep 8. Nature. 2021. PMID: 34497420 Free PMC article.
We find that duloxetine binds to several metabolic enzymes and changes the metabolite secretion of the respective bacteria. When tested in a defined microbial community of accumulators and non-accumulators, duloxetine markedly altered the composition of the communit …
We find that duloxetine binds to several metabolic enzymes and changes the metabolite secretion of the respective bacteria. When test …
Prurigo successfully treated with duloxetine hydrochloride.
Hashimoto T, Satoh T, Yokozeki H. Hashimoto T, et al. Australas J Dermatol. 2019 Aug;60(3):237-239. doi: 10.1111/ajd.12996. Epub 2019 Jan 24. Australas J Dermatol. 2019. PMID: 30675900
We report here two cases with treatment-resistant prurigo that were successfully treated with duloxetine hydrochloride, a serotonin-norepinephrine reuptake inhibitor. ...Duloxetine hydrochloride appears to be useful for treating prurigo via modulating …
We report here two cases with treatment-resistant prurigo that were successfully treated with duloxetine hydrochloride, a sero …
Serotonin and Norepinephrine Reuptake Inhibitors.
Shelton RC. Shelton RC. Handb Exp Pharmacol. 2019;250:145-180. doi: 10.1007/164_2018_164. Handb Exp Pharmacol. 2019. PMID: 30838456
It is approved in the narrow dose range of 50-100 mg per day. Duloxetine is a more potent 5-HT and NE reuptake inhibitor with a more balanced profile of binding at about 10:1 for 5HT and NE transporter binding. It is also a moderate inhibitor of CYP2D6, so that modest dose …
It is approved in the narrow dose range of 50-100 mg per day. Duloxetine is a more potent 5-HT and NE reuptake inhibitor with a more …
2,055 results