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Eszopiclone.
[No authors listed] [No authors listed] 2023 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000277 Free Books & Documents. Review.
No data are available on the use of eszopiclone during breastfeeding. Data from the racemate, zopiclone, indicate that occasional use while breastfeeding an older infant should pose little risk to the infant. ...
No data are available on the use of eszopiclone during breastfeeding. Data from the racemate, zopiclone, indicate that occasional use …
Eszopiclone.
[No authors listed] [No authors listed] 2018 Feb 20. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2018 Feb 20. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643378 Free Books & Documents. Review.
Eszopiclone is a benzodiazepine receptor agonist that is used for the treatment of insomnia. Eszopiclone has not been implicated in causing serum enzyme elevations or clinically apparent liver injury....
Eszopiclone is a benzodiazepine receptor agonist that is used for the treatment of insomnia. Eszopiclone has not been implicat …
Eszopiclone for insomnia.
Melton ST, Wood JM, Kirkwood CK. Melton ST, et al. Ann Pharmacother. 2005 Oct;39(10):1659-66. doi: 10.1345/aph.1G179. Epub 2005 Aug 30. Ann Pharmacother. 2005. PMID: 16131537 Review.
OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy data, and adverse effects of eszopiclone in the treatment of transient and chronic insomnia in adult and geriatric patients. ...The results of the 6-month, open-label extension trial demonstrated that improv …
OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy data, and adverse effects of eszopiclone in the treatment of transi …
Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis.
De Crescenzo F, D'Alò GL, Ostinelli EG, Ciabattini M, Di Franco V, Watanabe N, Kurtulmus A, Tomlinson A, Mitrova Z, Foti F, Del Giovane C, Quested DJ, Cowen PJ, Barbui C, Amato L, Efthimiou O, Cipriani A. De Crescenzo F, et al. Lancet. 2022 Jul 16;400(10347):170-184. doi: 10.1016/S0140-6736(22)00878-9. Lancet. 2022. PMID: 35843245 Free article.
For long-term treatment, eszopiclone and lemborexant were more effective than placebo (eszopiclone: SMD 0.63 [95% CI 0.36-0.90; very low]; lemborexant: 0.41 [0.04-0.78; very low]) and eszopiclone was more effective than ramelteon (0.63 [0.16-1.10; very low]) …
For long-term treatment, eszopiclone and lemborexant were more effective than placebo (eszopiclone: SMD 0.63 [95% CI 0.36-0.90 …
Eszopiclone: a review of its use in the treatment of insomnia.
Hair PI, McCormack PL, Curran MP. Hair PI, et al. Drugs. 2008;68(10):1415-34. doi: 10.2165/00003495-200868100-00005. Drugs. 2008. PMID: 18578559 Review.
On discontinuation of eszopiclone, there was no rebound insomnia or serious withdrawal effects. ...Unlike most other hypnotics, eszopiclone is not limited to short-term use....
On discontinuation of eszopiclone, there was no rebound insomnia or serious withdrawal effects. ...Unlike most other hypnotics, es …
Insomnia Management: A Review and Update.
Shaha DP. Shaha DP. J Fam Pract. 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620. J Fam Pract. 2023. PMID: 37549414 Free PMC article. Review.
Pharmacologic agents that are approved by the US Food and Drug Administration for insomnia include benzodiazepine receptor agonists (zolpidem, eszopiclone, and zaleplon), low-dose doxepin (tricyclic antidepressant), ramelteon (melatonin receptor agonist), and dual orexin r …
Pharmacologic agents that are approved by the US Food and Drug Administration for insomnia include benzodiazepine receptor agonists (zolpide …
Eszopiclone for late-life insomnia.
McCrae CS, Ross A, Stripling A, Dautovich ND. McCrae CS, et al. Clin Interv Aging. 2007;2(3):313-26. Clin Interv Aging. 2007. PMID: 18044182 Free PMC article. Review.
Clinical studies in younger adults (mean = 44 years) have shown eszopiclone can be used for 6-12 months without evidence of problems. ...Cognitive-behavioral therapy for insomnia, which effectively targets the behavioral factors that maintain chronic insomnia, represents a …
Clinical studies in younger adults (mean = 44 years) have shown eszopiclone can be used for 6-12 months without evidence of problems. …
Eszopiclone for the treatment of insomnia.
Scharf M. Scharf M. Expert Opin Pharmacother. 2006 Feb;7(3):345-56. doi: 10.1517/14656566.7.3.345. Expert Opin Pharmacother. 2006. PMID: 16448328 Review.

Nightly treatment with eszopiclone 1 mg effectively induced sleep in elderly patients and the 2-mg dose effectively induced and maintained sleep. ...Eszopiclone was well tolerated in clinical trials < or = 12 months duration, with no clinically significant eviden

…
Nightly treatment with eszopiclone 1 mg effectively induced sleep in elderly patients and the 2-mg dose effectively induced and maint …
Eszopiclone.
Halas CJ. Halas CJ. Am J Health Syst Pharm. 2006 Jan 1;63(1):41-8. doi: 10.2146/ajhp050357. Am J Health Syst Pharm. 2006. PMID: 16373464
PURPOSE: The pharmacology, pharmacokinetics, indications, clinical efficacy, adverse effects, drug interactions, dosing, and administration of eszopiclone are discussed. SUMMARY: The pharmacology of eszopiclone is not well understood. Eszopiclone is the S-iso …
PURPOSE: The pharmacology, pharmacokinetics, indications, clinical efficacy, adverse effects, drug interactions, dosing, and administration …
Eszopiclone, a nonbenzodiazepine sedative-hypnotic agent for the treatment of transient and chronic insomnia.
Najib J. Najib J. Clin Ther. 2006 Apr;28(4):491-516. doi: 10.1016/j.clinthera.2006.04.014. Clin Ther. 2006. PMID: 16750462 Review.
In vitro studies have indicated that the cytochrome P450 (CYP) isozymes CYP3A4 and CYP2E1 are involved in the biotransformation of eszopiclone; therefore, drugs that induce or inhibit these CYP isozymes may affect the metabolism of eszopiclone. Eszopiclone is …
In vitro studies have indicated that the cytochrome P450 (CYP) isozymes CYP3A4 and CYP2E1 are involved in the biotransformation of eszopi …
347 results

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