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1974 4
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2000 100
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2,189 results

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The ventilatory depressant actions but not the antinociceptive effects of morphine are blunted in rats receiving intravenous infusion of L-cysteine ethyl ester.
Lewis THJ, May WJ, Young AP, Bates JN, Baby SM, Getsy PM, Ryan RM, Hsieh YH, Seckler JM, Lewis SJ. Lewis THJ, et al. Biomed Pharmacother. 2022 Dec;156:113939. doi: 10.1016/j.biopha.2022.113939. Epub 2022 Oct 28. Biomed Pharmacother. 2022. PMID: 36411626 Free PMC article.
This study demonstrates that intravenous infusion of the cell-penetrant thiol ester, L-cysteine ethyl ester (L-CYSee), to adult male Sprague-Dawley rats elicited (a) minor alterations in frequency of breathing, expiratory time, tidal volume, minute ventilation, or e …
This study demonstrates that intravenous infusion of the cell-penetrant thiol ester, L-cysteine ethyl ester (L-CYSee), to adul …
L-Cysteine ethyl ester reverses the deleterious effects of morphine on, arterial blood-gas chemistry in tracheotomized rats.
Mendoza J, Passafaro R, Baby S, Young AP, Bates JN, Gaston B, Lewis SJ. Mendoza J, et al. Respir Physiol Neurobiol. 2013 Oct 1;189(1):136-43. doi: 10.1016/j.resp.2013.07.007. Epub 2013 Jul 23. Respir Physiol Neurobiol. 2013. PMID: 23892097 Free PMC article.
This study determined whether the membrane-permeable ventilatory stimulant, L-cysteine ethylester (L-CYSee), reversed the deleterious actions of morphine on arterial blood-gas chemistry in isoflurane-anesthetized rats. ...Injections of L-CYSee (100 mumol/kg, i.v.) reversed …
This study determined whether the membrane-permeable ventilatory stimulant, L-cysteine ethylester (L-CYSee), reversed the deleterious …
D-cysteine ethyl ester and D-cystine dimethyl ester reverse the deleterious effects of morphine on arterial blood-gas chemistry and Alveolar-arterial gradient in anesthetized rats.
Getsy PM, Young AP, Grossfield A, Seckler JM, Wilson CG, Gaston B, Bates JN, Lewis SJ. Getsy PM, et al. Respir Physiol Neurobiol. 2022 Aug;302:103912. doi: 10.1016/j.resp.2022.103912. Epub 2022 Apr 18. Respir Physiol Neurobiol. 2022. PMID: 35447347 Free PMC article.
We determined whether intravenous injections of the membrane-permeable ventilatory stimulants, D-cysteine ethyl ester (ethyl (2 S)- 2-amino-3-sulfanylpropanoate) (D-CYSee) and D-cystine dimethyl ester (methyl (2 S)- 2-amino-3-[[(2 S)- 2-amino-3-methoxy-3-oxop …
We determined whether intravenous injections of the membrane-permeable ventilatory stimulants, D-cysteine ethyl ester (ethy …
Metabolism of 99mTc-L,L-ethyl cysteinate dimer in healthy volunteers.
Walovitch RC, Franceschi M, Picard M, Cheesman EH, Hall KM, Makuch J, Watson MW, Zimmerman RE, Watson AD, Ganey MV, et al. Walovitch RC, et al. Neuropharmacology. 1991 Mar;30(3):283-92. doi: 10.1016/0028-3908(91)90156-6. Neuropharmacology. 1991. PMID: 1906585
99mTc-L,L-Ethyl cysteinate dimer (ECD) is a brain-perfusion imaging agent, which exhibits selective retention in brain and rapid renal excretion. ...They were identified in the urine as the 99mTc ethylenediylbis-L-cysteine, monoethyl ester complex (ECM) and the 99mT …
99mTc-L,L-Ethyl cysteinate dimer (ECD) is a brain-perfusion imaging agent, which exhibits selective retention in brain and rapid rena …
Mass spectrometric analysis of L-cysteine metabolism: physiological role and fate of L-cysteine in the enteric protozoan parasite Entamoeba histolytica.
Jeelani G, Sato D, Soga T, Watanabe H, Nozaki T. Jeelani G, et al. mBio. 2014 Nov 4;5(6):e01995. doi: 10.1128/mBio.01995-14. mBio. 2014. PMID: 25370494 Free PMC article.
These metabolites were identified as thiazolidine-4-carboxylic acid (T4C), 2-methyl thiazolidine-4-carboxylic acid (MT4C), and 2-ethyl-thiazolidine-4-carboxylic acid (ET4C), the condensation products of L-cysteine with aldehydes. We demonstrated that these 2-(R)-thi …
These metabolites were identified as thiazolidine-4-carboxylic acid (T4C), 2-methyl thiazolidine-4-carboxylic acid (MT4C), and 2-ethyl …
s-Ethyl cysteine, an amino acid derivative, attenuated cisplatin induced nephrotoxicity.
Kuo HL, Mong MC, Chen HC, Wang ZH, Yin MC. Kuo HL, et al. Amino Acids. 2020 Aug;52(8):1181-1190. doi: 10.1007/s00726-020-02882-9. Epub 2020 Aug 13. Amino Acids. 2020. PMID: 32789693
Renal protection from s-ethyl cysteine (SEC) against cisplatin (CP)-induced inflammatory and oxidative injury was examined. ...
Renal protection from s-ethyl cysteine (SEC) against cisplatin (CP)-induced inflammatory and oxidative injury was examined. .. …
Preparation and properties of S-nitroso-L-cysteine ethyl ester, an intracellular nitrosating agent.
Clancy R, Cederbaum AI, Stoyanovsky DA. Clancy R, et al. J Med Chem. 2001 Jun 7;44(12):2035-8. doi: 10.1021/jm000463f. J Med Chem. 2001. PMID: 11384248
In this report, a protocol for the preparation of the hydrochloride of S-nitroso-L-cysteine ethyl ester (SNCEE.HCl; 2) is presented. The synthesis of 2 has been targeted because S-nitroso-L-cysteine (SNC; 2b), which is extensively used for trans-S-nitrosation …
In this report, a protocol for the preparation of the hydrochloride of S-nitroso-L-cysteine ethyl ester (SNCEE.HCl; 2) is pres …
L-Cysteine Catalyzed Environmentally Benign One-pot Multicomponent Approach Towards the Synthesis of Dihydropyrano[2,3-c]pyrazole Derivatives.
Sikandar S, Zahoor AF, Ahmad S, Anjum MN, Ahmad MN, Shah MSU. Sikandar S, et al. Curr Org Synth. 2020;17(6):457-463. doi: 10.2174/1570179417666200511092332. Curr Org Synth. 2020. PMID: 32392115
RESULTS AND DISCUSSION: We found that optimal conditions for the preparation of pyrano[2,3-c]pyrazoles were L-cysteine (0.5 mol) in the presence of water:ethanol (9:1) at 90 C. ...CONCLUSION: We described a green and environmentally benign method to synthesize pyrano[2,3-c …
RESULTS AND DISCUSSION: We found that optimal conditions for the preparation of pyrano[2,3-c]pyrazoles were L-cysteine (0.5 mol) in t …
Vibrational and structural behavior of (L)-cysteine ethyl ester hydrochloride in the solid state and in aqueous solution.
Defonsi Lestard ME, Díaz SB, Puiatti M, Echeverría GA, Piro OE, Pierini AB, Altabef AB, Tuttolomondo ME. Defonsi Lestard ME, et al. J Phys Chem A. 2013 Dec 27;117(51):14243-52. doi: 10.1021/jp409252d. Epub 2013 Dec 16. J Phys Chem A. 2013. PMID: 24328050
The aim of this work is to evaluate the vibrational and structural properties of l-cysteine ethyl ester hydrochloride (CE), and its electronic behavior mainly in relation to the action of the thiol and amine groups at different degrees of solvation. ...
The aim of this work is to evaluate the vibrational and structural properties of l-cysteine ethyl ester hydrochloride (CE), an …
2,189 results