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Year Number of Results
1955 1
1959 1
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1979 3
1980 6
1981 5
1982 10
1983 24
1984 21
1985 17
1986 23
1987 27
1988 31
1989 40
1990 30
1991 48
1992 35
1993 38
1994 21
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1996 32
1997 27
1998 27
1999 22
2000 12
2001 25
2002 25
2003 36
2004 26
2005 24
2006 26
2007 33
2008 20
2009 17
2010 19
2011 19
2012 19
2013 15
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2015 19
2016 10
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2018 10
2019 9
2020 21
2021 9
2022 8
2023 9
2024 4

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917 results

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Page 1
Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats.
Mikami K, Goto T, Miura K, Ohshima S, Yoneyama K, Lin JG, Watanabe D, Segawa D, Kataoka E, Shibuya T, Watanabe S. Mikami K, et al. J Gastroenterol. 2005 Mar;40(3):260-5. doi: 10.1007/s00535-004-1534-3. J Gastroenterol. 2005. PMID: 15830285
BACKGROUND: Gabexate mesilate, a synthetic protease inhibitor, is used to treat acute pancreatitis and disseminated intravascular coagulation because it inhibits various serine proteases; however, whether gabexate mesilate prevents acute liver failure …
BACKGROUND: Gabexate mesilate, a synthetic protease inhibitor, is used to treat acute pancreatitis and disseminated intravascu …
Efficacy of gabexate mesilate in preventing post endoscopic retrograde cholangiopancreatography pancreatitis: A meta-analysis of randomized clinical trials.
Chiu YJ, Chen SC, Kang YN, Hou SK, Chao CC, Chang CC. Chiu YJ, et al. J Formos Med Assoc. 2021 Apr;120(4):1090-1099. doi: 10.1016/j.jfma.2020.10.034. Epub 2020 Nov 9. J Formos Med Assoc. 2021. PMID: 33183879 Free article.
To enhance the understanding of this topic, this study aimed to provide overview of gabexate mesilate on preventing post ERCP pancreatitis (PEP) by synthesizing all relevant randomized controlled trials (RCTs). ...RESULTS: Thirteen RCTs with 3718 patients undergoing …
To enhance the understanding of this topic, this study aimed to provide overview of gabexate mesilate on preventing post ERCP …
Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies.
Minakata D, Fujiwara SI, Ikeda T, Kawaguchi SI, Toda Y, Ito S, Ochi SI, Nagayama T, Mashima K, Umino K, Nakano H, Yamasaki R, Morita K, Kawasaki Y, Sugimoto M, Yamamoto C, Ashizawa M, Hatano K, Sato K, Oh I, Ohmine K, Muroi K, Ohmori T, Kanda Y. Minakata D, et al. Int J Hematol. 2019 Feb;109(2):141-146. doi: 10.1007/s12185-018-02567-w. Epub 2018 Dec 8. Int J Hematol. 2019. PMID: 30536180
We evaluated clinical outcomes of disseminated intravascular coagulation (DIC) in patients with hematological malignancies treated with synthetic protease inhibitors (SPIs) and compared the effects of gabexate mesilate (FOY) and nafamostat mesilate (FUT). We …
We evaluated clinical outcomes of disseminated intravascular coagulation (DIC) in patients with hematological malignancies treated with synt …
Gabexate mesilate in human acute pancreatitis.
Yoshida T. Yoshida T. Gastroenterology. 1993 Dec;105(6):1922-3. doi: 10.1016/0016-5085(93)91102-n. Gastroenterology. 1993. PMID: 8253373 No abstract available.
Gabexate mesilate, a synthetic protease inhibitor, attenuates endotoxin-induced pulmonary vascular injury by inhibiting tumor necrosis factor production by monocytes.
Murakami K, Okajima K, Uchiba M, Okabe H, Takatsuki K. Murakami K, et al. Crit Care Med. 1996 Jun;24(6):1047-53. doi: 10.1097/00003246-199606000-00027. Crit Care Med. 1996. PMID: 8681572
Intravenous administration of endotoxin significantly increased pulmonary vascular permeability. Gabexate mesilate significantly inhibited pulmonary vascular injury observed 6 hrs after the administration of endotoxin. ...CONCLUSION: Our findings suggest that gab …
Intravenous administration of endotoxin significantly increased pulmonary vascular permeability. Gabexate mesilate significant …
Gabexate mesilate, a synthetic protease inhibitor, reduces ischemia/reperfusion injury of rat liver by inhibiting leukocyte activation.
Harada N, Okajima K, Kushimoto S. Harada N, et al. Crit Care Med. 1999 Sep;27(9):1958-64. doi: 10.1097/00003246-199909000-00040. Crit Care Med. 1999. PMID: 10507625
To determine whether gabexate mesilate inhibits leukocyte activation, we examined the effects of gabexate mesilate on hepatic concentrations of tumor necrosis factor-alpha and rat interleukin-8 and on hepatic myeloperoxidase activity after ischemia/rep …
To determine whether gabexate mesilate inhibits leukocyte activation, we examined the effects of gabexate mesilate …
Gabexate mesilate in human acute pancreatitis. German Pancreatitis Study Group.
Büchler M, Malfertheiner P, Uhl W, Schölmerich J, Stöckmann F, Adler G, Gaus W, Rolle K, Beger HG. Büchler M, et al. Gastroenterology. 1993 Apr;104(4):1165-70. doi: 10.1016/0016-5085(93)90288-n. Gastroenterology. 1993. PMID: 8462805 Clinical Trial.
BACKGROUND: A multicenter controlled study was performed to evaluate the effect of high doses of the low molecular weight protease inhibitor gabexate mesilate on mortality and complications associated with moderate and severe acute pancreatitis. ...RESULTS: There wa …
BACKGROUND: A multicenter controlled study was performed to evaluate the effect of high doses of the low molecular weight protease inhibitor …
Gabexate mesilate, a synthetic anticoagulant, inhibits the expression of endothelial leukocyte adhesion molecules in vitro.
Uchiba M, Okajima K, Kaun C, Binder BR, Wojta J. Uchiba M, et al. Crit Care Med. 2003 Apr;31(4):1147-53. doi: 10.1097/01.CCM.0000060005.48885.2B. Crit Care Med. 2003. PMID: 12682486
We examined whether gabexate mesilate inhibits tumor necrosis factor-alpha-induced expression of leukocyte adhesion molecules in cultured endothelial cells. ...Inhibition of nuclear factor-kappaB activation by gabexate mesilate could be explained by in …
We examined whether gabexate mesilate inhibits tumor necrosis factor-alpha-induced expression of leukocyte adhesion molecules …
Gabexate mesilate suppresses influenza pneumonia in mice through inhibition of cytokines.
Kosai K, Seki M, Yanagihara K, Nakamura S, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, Kohno S. Kosai K, et al. J Int Med Res. 2008 Mar-Apr;36(2):322-8. doi: 10.1177/147323000803600215. J Int Med Res. 2008. PMID: 18380943 Free article.
Gabexate mesilate is a synthetic protease inhibitor that is effective for acute pancreatitis. The effect of gabexate mesilate in influenza pneumonia in mice was investigated by examining the changes in pulmonary inflammatory cytokines and chemokines. . …
Gabexate mesilate is a synthetic protease inhibitor that is effective for acute pancreatitis. The effect of gabexate …
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