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Page 1
Itraconazole.
Piérard GE, Arrese JE, Piérard-Franchimont C. Piérard GE, et al. Expert Opin Pharmacother. 2000 Jan;1(2):287-304. doi: 10.1517/14656566.1.2.287. Expert Opin Pharmacother. 2000. PMID: 11249550 Review.
Itraconazole is a broad spectrum triazole antifungal agent. It has favourable pharmacodynamic and pharmacokinetic profiles and is available as both oral and i.v. formulations. ...Itraconazole has been well-tolerated with doses of up to 400 mg/day being generally fre …
Itraconazole is a broad spectrum triazole antifungal agent. It has favourable pharmacodynamic and pharmacokinetic profiles and is ava …
Repurposed itraconazole for use in the treatment of malignancies as a promising therapeutic strategy.
Li CL, Fang ZX, Wu Z, Hou YY, Wu HT, Liu J. Li CL, et al. Biomed Pharmacother. 2022 Oct;154:113616. doi: 10.1016/j.biopha.2022.113616. Epub 2022 Aug 30. Biomed Pharmacother. 2022. PMID: 36055112 Free article. Review.
To explore the potential utilization of itraconazole in different types of malignancies, we retrieved the published literature relating to itraconazole in cancer and reviewed the mechanisms of itraconazole in preclinical and clinical cancer studies. Current r …
To explore the potential utilization of itraconazole in different types of malignancies, we retrieved the published literature relati …
Intravenous itraconazole.
Slain D, Rogers PD, Cleary JD, Chapman SW. Slain D, et al. Ann Pharmacother. 2001 Jun;35(6):720-9. doi: 10.1345/aph.10262. Ann Pharmacother. 2001. PMID: 11408991 Review.
Due to the paucity of published information concerning the pharmacokinetics, efficacy, and safety of the intravenous formulation of intravenous itraconazole, additional information was obtained from the manufacturer. ...This formulation provides quicker and more consistent …
Due to the paucity of published information concerning the pharmacokinetics, efficacy, and safety of the intravenous formulation of intraven …
Pharmacology of itraconazole.
De Beule K, Van Gestel J. De Beule K, et al. Drugs. 2001;61 Suppl 1:27-37. doi: 10.2165/00003495-200161001-00003. Drugs. 2001. PMID: 11219548 Review.
Itraconazole is highly efficacious, particularly because its main metabolite, hydroxy-itraconazole, also has considerable antifungal activity. ...These formulations combine lipophilic itraconazole with hydroxypropyl-beta-cyclodextrin, a ring of substituted gl …
Itraconazole is highly efficacious, particularly because its main metabolite, hydroxy-itraconazole, also has considerable anti …
Itraconazole: pharmacokinetics and indications.
Negroni R, Arechavala AI. Negroni R, et al. Arch Med Res. 1993 Winter;24(4):387-93. Arch Med Res. 1993. PMID: 8118163 Review.
Itraconazole is a highly lipophilic triazolic compound, scarcely soluble in acidified polyethylene glycol, and soluble in hydroxypropyl-beta-cyclodextrin. ...In the skin and particularly nails, itraconazole persists for a long time after discontinuation of therapy. …
Itraconazole is a highly lipophilic triazolic compound, scarcely soluble in acidified polyethylene glycol, and soluble in hydroxyprop …
Itraconazole in cyclodextrin solution.
Stevens DA. Stevens DA. Pharmacotherapy. 1999 May;19(5):603-11. doi: 10.1592/phco.19.8.603.31529. Pharmacotherapy. 1999. PMID: 10331823 Review.
Itraconazole, a water-insoluble oral triazole antifungal, has been formulated in cyclodextrin as a solution. ...This enables solubilization and delivery to the lipid interface of the gut lumen, resulting in absorption of the guest molecule without absorption of the ring. T …
Itraconazole, a water-insoluble oral triazole antifungal, has been formulated in cyclodextrin as a solution. ...This enables solubili …
Itraconazole--perspectives for the management of invasive aspergillosis.
Groll AH. Groll AH. Mycoses. 2002;45 Suppl 3:48-55. doi: 10.1111/j.1439-0507.2002.tb04770.x. Mycoses. 2002. PMID: 12690972 Review.
Itraconazole has become an important option in the management of invasive aspergillosis. ...Itraconazole has an important role for consolidation and maintenance therapy of patients with invasive aspergillosis, and novel combination therapies involving itraconazol …
Itraconazole has become an important option in the management of invasive aspergillosis. ...Itraconazole has an important role …
[Pharmacokinetics of itraconazole].
Cauwenbergh G. Cauwenbergh G. Mycoses. 1994;37 Suppl 2:27-33. Mycoses. 1994. PMID: 7609740 Review. German.
Itraconazole is a lipophilic triazole antifungal with a broad spectrum of activity. ...Itraconazole levels are decreased by rifampicin, phenytoin and phenobarbital. ...
Itraconazole is a lipophilic triazole antifungal with a broad spectrum of activity. ...Itraconazole levels are decreased by ri …
Itraconazole for the treatment of onychomycosis.
Gupta AK, De Doncker P, Scher RK, Haneke E, Daniel CR 3rd, André J, Baran R. Gupta AK, et al. Int J Dermatol. 1998 Apr;37(4):303-8. doi: 10.1046/j.1365-4362.1998.00360.x. Int J Dermatol. 1998. PMID: 9585906 Review.
The pharmacokinetics of itraconazole in the nail results in drug remaining at therapeutic levels for 6-9 months after completion of therapy. METHODS: An overview of studies where continuous or pulse itraconazole therapy has been used in the treatment of fingernail a …
The pharmacokinetics of itraconazole in the nail results in drug remaining at therapeutic levels for 6-9 months after completion of t …
"Hedgehog pathway": a potential target of itraconazole in the treatment of cancer.
Wei X, Liu W, Wang JQ, Tang Z. Wei X, et al. J Cancer Res Clin Oncol. 2020 Feb;146(2):297-304. doi: 10.1007/s00432-019-03117-5. Epub 2020 Jan 20. J Cancer Res Clin Oncol. 2020. PMID: 31960187 Review.
PURPOSE: Itraconazole is an antifungal drug that has been clinically used for over 30 years. ...In any case, an in-depth study on itraconazole will bring new hope for cancer patients in the near future....
PURPOSE: Itraconazole is an antifungal drug that has been clinically used for over 30 years. ...In any case, an in-depth study on …
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