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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 2
1998 8
1999 13
2000 12
2001 24
2002 25
2003 48
2004 48
2005 76
2006 53
2007 65
2008 82
2009 84
2010 92
2011 86
2012 103
2013 96
2014 130
2015 111
2016 97
2017 118
2018 117
2019 94
2020 78
2021 84
2022 75
2023 62
2024 28

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1,704 results

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Page 1
The Optimization of the Synthesis Process and the Identification of Levobupivacaine Hydrochloride.
Yan Q, Gan H, Li C, Gui G, Wang J, Zha X. Yan Q, et al. Molecules. 2023 Nov 8;28(22):7482. doi: 10.3390/molecules28227482. Molecules. 2023. PMID: 38005204 Free PMC article.
In this study, we not only optimized and improved the synthesis process of levobupivacaine hydrochloride (21) but also conducted a comprehensive exploration of critical industrial-scale production details, and a novel high-performance liquid chromatography (HPLC) an …
In this study, we not only optimized and improved the synthesis process of levobupivacaine hydrochloride (21) but also conduct …
Clinical Pharmacokinetics and Pharmacodynamics of Levobupivacaine.
Heppolette CAA, Brunnen D, Bampoe S, Odor PM. Heppolette CAA, et al. Clin Pharmacokinet. 2020 Jun;59(6):715-745. doi: 10.1007/s40262-020-00868-0. Clin Pharmacokinet. 2020. PMID: 32034727 Review.
Levobupivacaine is a long-acting amide local anaesthetic used in analgesia and anaesthesia. ...A favourable safety and drug effect profile for levobupivacaine has led to widespread use. Levobupivacaine is generally well tolerated but dose adjustment is import
Levobupivacaine is a long-acting amide local anaesthetic used in analgesia and anaesthesia. ...A favourable safety and drug effect pr
Levobupivacaine plasma concentrations following repeat caudal anesthetics.
Frawley G, Cortinez LI, Anderson BJ, Bjorksten A, King S. Frawley G, et al. Paediatr Anaesth. 2022 Dec;32(12):1347-1354. doi: 10.1111/pan.14556. Epub 2022 Sep 25. Paediatr Anaesth. 2022. PMID: 36106368
Parameter estimates were used to simulate concentrations after a repeat levobupivacaine 2.5 mg kg(-1) caudal at 3 or 4 h following an initial levobupivacaine 2.5 mg kg(-1) caudal. ...Simulation of total plasma concentrations in neonates (7 kg, 57 weeks postmenstrual …
Parameter estimates were used to simulate concentrations after a repeat levobupivacaine 2.5 mg kg(-1) caudal at 3 or 4 h following an …
The Efficacy of Levobupivacaine Hydrochloride-Dexamethasone Infiltration for Post-Tonsillectomy Pain in Adults.
Bayram A, Doğan M, Cihan C, Karataş D, Gökahmetoğlu G, Özcan I. Bayram A, et al. J Craniofac Surg. 2015 Oct;26(7):e651-3. doi: 10.1097/SCS.0000000000001975. J Craniofac Surg. 2015. PMID: 26468853 Clinical Trial.
OBJECTIVE: The aim of the study is to evaluate the efficacy of peritonsillar infiltration of a levobupivacaine hydrochloride and dexamethasone combination for post-tonsillectomy pain in adult patients. ...The patients were equally randomized into 2 groups by means o …
OBJECTIVE: The aim of the study is to evaluate the efficacy of peritonsillar infiltration of a levobupivacaine hydrochloride a …
Levobupivacaine Thermogel for Long-acting Analgesia.
de Lima EN, de Andrade ARB, Leal LB, de Santana DP. de Lima EN, et al. AAPS PharmSciTech. 2018 Aug;19(6):2533-2542. doi: 10.1208/s12249-018-1083-3. Epub 2018 Jun 12. AAPS PharmSciTech. 2018. PMID: 29948983
The present research investigates development of thermogels containing poloxamer and levobupivacaine. All formulations were prepared by the cold method; the compatibilities of the excipients were evaluated by DSC, rheology and viscosities, transition temperature, syringeab …
The present research investigates development of thermogels containing poloxamer and levobupivacaine. All formulations were prepared …
[Levobupivacaine for regional anesthesia. A systematic review].
Urbanek B, Kapral S. Urbanek B, et al. Anaesthesist. 2006 Mar;55(3):296-313. doi: 10.1007/s00101-005-0941-z. Anaesthesist. 2006. PMID: 16341730 Review. German.
Epidural levobupivacaine was combined with fentanyl, morphine, sufentanil, epinephrine, and clonidine, spinal levobupivacaine was combined with sufentanil, fentanyl, and epinephrine. In most studies, levobupivacaine was compared to bupivacaine and/or ropivaca …
Epidural levobupivacaine was combined with fentanyl, morphine, sufentanil, epinephrine, and clonidine, spinal levobupivacaine
1,704 results