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Year Number of Results
1992 1
1995 10
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1997 5
1998 6
1999 7
2000 13
2001 12
2002 14
2003 18
2004 13
2005 14
2006 10
2007 19
2008 17
2009 25
2010 20
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2012 37
2013 24
2014 24
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2016 6
2017 12
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2020 5
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345 results

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Page 1
Hydrochlorothiazide/Losartan Potassium Tablet Prepared by Direct Compression.
Luo Q, Zhang Q, Wang P. Luo Q, et al. Pharmaceutics. 2022 Aug 21;14(8):1741. doi: 10.3390/pharmaceutics14081741. Pharmaceutics. 2022. PMID: 36015367 Free PMC article.
Hydrochlorothiazide (HCTZ)/losartan potassium (LOS-K) was used as a model drug to prepare compound tablets through the investigation of the compression and mechanical properties of mixed powders to determine the formulation and preparation factors, fol …
Hydrochlorothiazide (HCTZ)/losartan potassium (LOS-K) was used as a model drug to prepare compound tablets throu …
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
Xie M, Tang T, Liang H. Xie M, et al. Clin Cardiol. 2023 Aug;46(8):886-898. doi: 10.1002/clc.24082. Epub 2023 Jul 11. Clin Cardiol. 2023. PMID: 37432701 Free PMC article. Review.
This study aimed to evaluate the efficacy of single-pill combination (SPC) antihypertensive drugs in patients with uncontrolled essential hypertension. ...The results of the network meta-analysis showed that a total of 11 single-pill combination antihypertensive dru …
This study aimed to evaluate the efficacy of single-pill combination (SPC) antihypertensive drugs in patients with uncontrolled essen …
An association of losartan-hydrochlorothiazide, but not losartan-furosemide, completely arrests progressive injury in the remnant kidney.
Arias SC, Souza RA, Malheiros DM, Fanelli C, Fujihara CK, Zatz R. Arias SC, et al. Am J Physiol Renal Physiol. 2016 Jan 15;310(2):F135-43. doi: 10.1152/ajprenal.00388.2015. Epub 2015 Nov 4. Am J Physiol Renal Physiol. 2016. PMID: 26538442 Free article.
At this time, Nx rats were distributed among the following four groups: untreated Nx rats, Nx rats that received losartan, Nx rats that received losartan + hydrochlorothiazide, and Nx rats that received losartan + furosemide. ...The losartan + f …
At this time, Nx rats were distributed among the following four groups: untreated Nx rats, Nx rats that received losartan, Nx rats th …
A risk-benefit assessment of losartan potassium in the treatment of hypertension.
Burrell LM. Burrell LM. Drug Saf. 1997 Jan;16(1):56-65. doi: 10.2165/00002018-199716010-00004. Drug Saf. 1997. PMID: 9010643 Review.
When losartan potassium is combined with hydrochlorothiazide there is a further reduction in blood pressure. ...Losartan potassium increases uric acid secretion and lowers plasma uric acid levels, which may be of benefit when losartan …
When losartan potassium is combined with hydrochlorothiazide there is a further reduction in blood pressure. ... …
Losartan potassium: a review of its pharmacology, clinical efficacy and tolerability in the management of hypertension.
Goa KL, Wagstaff AJ. Goa KL, et al. Drugs. 1996 May;51(5):820-45. doi: 10.2165/00003495-199651050-00008. Drugs. 1996. PMID: 8861549 Review.
Losartan potassium combined with hydrochlorothiazide reduces blood pressure further than either drug given separately. ...The adverse effect profile of the losartan potassium-hydrochlorothiazide combination resembles …
Losartan potassium combined with hydrochlorothiazide reduces blood pressure further than either drug give …
A Rare Culprit of Methemoglobinemia.
Fadah K, Rivera M, Lingireddy A, Kalas MA, Ghafouri RS, Deoker A. Fadah K, et al. J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221117919. doi: 10.1177/23247096221117919. J Investig Med High Impact Case Rep. 2022. PMID: 35959982 Free PMC article.
In this case, there was an acute rise in methemoglobin levels following initiation of an hydrochlorothiazide-losartan combination, which improved following the discontinuation of hydrochlorothiazide. Extensive workup ruled out cytochrome b5 reductase ( …
In this case, there was an acute rise in methemoglobin levels following initiation of an hydrochlorothiazide-losartan combi …
Fimasartan: A New Angiotensin Receptor Blocker.
Lee HY, Oh BH. Lee HY, et al. Drugs. 2016 Jul;76(10):1015-22. doi: 10.1007/s40265-016-0592-1. Drugs. 2016. PMID: 27272555 Review.
Fimasartan is the ninth, and most recent, angiotensin II receptor antagonist approved as an antihypertensive agent. Fimasartan, a pyrimidin-4(3H)-one derivative of losartan with the imidazole ring replaced, which enables higher potency and longer duration than losartan …
Fimasartan is the ninth, and most recent, angiotensin II receptor antagonist approved as an antihypertensive agent. Fimasartan, a pyrimidin- …
Determination of losartan potassium, quinapril hydrochloride and hydrochlorothiazide in pharmaceutical preparations using derivative spectrophotometry and chromatographic-densitometric method.
Stolarczyk M, Maślanka A, Apola A, Krzek J. Stolarczyk M, et al. Acta Pol Pharm. 2013 Nov-Dec;70(6):967-76. Acta Pol Pharm. 2013. PMID: 24383320 Free article.
Two methods, spectrophotometric and chromatographic-densitometric ones, were developed for determination of losartan potassium, quinapril hydrochloride and hydrochlorothiazide in pharmaceutical preparations. ...Retardation factor for quinapril hydrochloride w …
Two methods, spectrophotometric and chromatographic-densitometric ones, were developed for determination of losartan potassium …
Development and validation of an analytical method for trace-level quantification of genotoxic nitrosamine impurities in losartan and hydrochlorothiazide fixed-dose combination tablets using ultra performance liquid chromatography triple quadrupole mass spectrometry.
Patel R, Purohit S, Solanki R, Khunt D, Patel C, Patel R, Parikh S. Patel R, et al. Rapid Commun Mass Spectrom. 2023 Apr 30;37(8):e9488. doi: 10.1002/rcm.9488. Rapid Commun Mass Spectrom. 2023. PMID: 36740827 Review.
Beginning with the class of pharmaceuticals known as sartans, subsequent lines of inquiry included antidiabetic medicines, antihistamines, and antibiotics. A critical review of the U.S. Food and Drug Administration database reveals that the highest number of products recal …
Beginning with the class of pharmaceuticals known as sartans, subsequent lines of inquiry included antidiabetic medicines, antihistamines, a …
A multivariate approach for the simultaneous determination of losartan potassium and hydrochlorothiazide in a combined pharmaceutical tablet formulation.
Maggio RM, Castellano PM, Kaufman TS. Maggio RM, et al. Anal Bioanal Chem. 2008 Aug;391(8):2949-55. doi: 10.1007/s00216-008-2180-z. Epub 2008 Jun 5. Anal Bioanal Chem. 2008. PMID: 18528688
A convenient new method for the simultaneous determination of losartan potassium and hydrochlorothiazide, with minimum sample pretreatment, is described. The procedure, based on the multivariate analysis of spectral data in the 220-274 nm region by the partia …
A convenient new method for the simultaneous determination of losartan potassium and hydrochlorothiazide, with minimum …
345 results