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Development of Fast Disintegrating Tablets Containing Loxoprofen Sodium by HYDROFLASH Manufacturing Method.
Kuwata A, Ono T, Tsuchiya Y, Yonemochi E. Kuwata A, et al. Chem Pharm Bull (Tokyo). 2024;72(1):48-55. doi: 10.1248/cpb.c23-00520. Chem Pharm Bull (Tokyo). 2024. PMID: 38171904 Free article.
In order to create and offer superior pharmaceuticals for consumers who wish to be relieved of headache and fever as soon as possible, we established HYDROFLASH manufacturing method that enables us to offer fast disintegration tablets containing loxoprofen sodium (L …
In order to create and offer superior pharmaceuticals for consumers who wish to be relieved of headache and fever as soon as possible, we es …
Evaluation of the Percutaneous Absorption of Drug Molecules in Zebrafish.
Morikane D, Zang L, Nishimura N. Morikane D, et al. Molecules. 2020 Aug 31;25(17):3974. doi: 10.3390/molecules25173974. Molecules. 2020. PMID: 32878194 Free PMC article.
Here, we developed a novel protocol for percutaneous absorption of molecules via the zebrafish tail skin, by applying a liquid solution directly, or using a filter paper imbibed with a chemical solution (coating). Human skin is capable of absorbing felbinac and loxoprofen …
Here, we developed a novel protocol for percutaneous absorption of molecules via the zebrafish tail skin, by applying a liquid solution dire …
Is epidural analgesia necessary after video-assisted thoracoscopic lobectomy?
Kamiyoshihara M, Nagashima T, Ibe T, Atsumi J, Shimizu K, Takeyoshi I. Kamiyoshihara M, et al. Asian Cardiovasc Thorac Ann. 2010 Oct;18(5):464-8. doi: 10.1177/0218492310381817. Asian Cardiovasc Thorac Ann. 2010. PMID: 20947601
The continuous subcutaneous analgesia catheter for morphine (2 mg in 48 h) was removed from 15 patients on postoperative day 1, and from the other 15 on day 2. We administered loxoprofen sodium hydrate, diclofenac sodium suppository, pentazocine hydroc …
The continuous subcutaneous analgesia catheter for morphine (2 mg in 48 h) was removed from 15 patients on postoperative day 1, and from the …
Lamotrigine for intractable migraine-like headaches in Sturge-Weber syndrome.
Nomura S, Shimakawa S, Fukui M, Tanabe T, Tamai H. Nomura S, et al. Brain Dev. 2014 May;36(5):399-401. doi: 10.1016/j.braindev.2013.06.009. Epub 2013 Jul 19. Brain Dev. 2014. PMID: 23877022
In addition, after 14years of age, the pulsating headaches were preceded by photophobia without homonymous hemianopsia and occurred almost daily. Headache pains were not improved by acetaminophen or loxoprofen sodium hydrate. Furthermore, various prophylactic …
In addition, after 14years of age, the pulsating headaches were preceded by photophobia without homonymous hemianopsia and occurred almost d …
Medication use before and during pregnancy in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.
Noda A, Obara T, Shirota M, Ueno F, Matsuzaki F, Hatanaka R, Obara R, Morishita K, Shinoda G, Orui M, Murakami K, Ishikuro M, Kuriyama S. Noda A, et al. Eur J Clin Pharmacol. 2024 Apr 17. doi: 10.1007/s00228-024-03685-7. Online ahead of print. Eur J Clin Pharmacol. 2024. PMID: 38630193
The proportion of pregnant women using medications was 49.0% prior to pregnancy diagnosis, 52.1% from diagnosis to week 12, and 58.4% post week 12 of pregnancy. The most frequently prescribed medications were loxoprofen sodium hydrate (5.5%) prior to pregnanc …
The proportion of pregnant women using medications was 49.0% prior to pregnancy diagnosis, 52.1% from diagnosis to week 12, and 58.4% post w …
[A Case Report of Kampo Medicine Improving the Symptoms of Antiresorptive Agent-related Osteonecrosis of the Jaw (ARONJ)].
Yamazaki Y, Shimada M. Yamazaki Y, et al. Yakugaku Zasshi. 2021;141(9):1123-1127. doi: 10.1248/yakushi.21-00128. Yakugaku Zasshi. 2021. PMID: 34471013 Free article. Japanese.
She was diagnosed with left mandibular osteomyelitis based on head computed tomography examination findings. The pain did not reduce even with amoxicillin and loxoprofen sodium hydrate. The patient was then referred to our clinic for treatment. Hainosankyuto …
She was diagnosed with left mandibular osteomyelitis based on head computed tomography examination findings. The pain did not reduce even wi …
Giant Gastric Antral Ulcer Developing After Short-Term NSAID Administration.
Yamane T, Ishii T, Umeda A, Takeda A, Shimao H, Morisane T. Yamane T, et al. Gastroenterology Res. 2011 Dec;4(6):294-296. doi: 10.4021/gr382w. Epub 2011 Nov 20. Gastroenterology Res. 2011. PMID: 27957032 Free PMC article.
A 61-year-old man took loxoprofen sodium hydrate, a prodrug NSAID, for acute upper respiratory infection for 5 days, developed melena 2 days later, and was admitted to our hospital. ...
A 61-year-old man took loxoprofen sodium hydrate, a prodrug NSAID, for acute upper respiratory infection for 5 days, de …
[Quantitative evaluation method of the informational value of initial symptoms based on Bayesian theory].
Ohshima S, Ieda M, Yamamoto M, Kobayashi D. Ohshima S, et al. Yakugaku Zasshi. 2012;132(6):763-8. doi: 10.1248/yakushi.132.763. Yakugaku Zasshi. 2012. PMID: 22687735 Free article. Japanese.
First, we calculated using the data from the clinical trials. For liver damage caused by loxoprofen sodium hydrate, the LR(+) was as high as 27.9 in the presence of rash, but the PP was 0.002067, which means there were only 2 liver damage cases among 1000 ras …
First, we calculated using the data from the clinical trials. For liver damage caused by loxoprofen sodium hydrate, the …