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1976 1
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Page 1
Effects of ibudilast on calcium deposition in soft tissues of rabbits with atherosclerosis.
Yasui M, Ota K, Oshima A. Yasui M, et al. J Int Med Res. 1990 Sep-Oct;18(5):415-24. doi: 10.1177/030006059001800510. J Int Med Res. 1990. PMID: 2257963
Calcium concentrations in the frontal cortex and cerebellum were lower in ibudilast/nicomol-treated rabbits and in those fed a standard diet compared with those receiving a cholesterol-rich diet only. ...It is concluded that 2.5 mg/kg.day ibudilast plus 300 mg/kg.day ni …
Calcium concentrations in the frontal cortex and cerebellum were lower in ibudilast/nicomol-treated rabbits and in those fed a standa …
Effect of nicomol on HDL cholesterol level.
Watanabe M, Taketa K, Nagashima H, Yamamoto Y. Watanabe M, et al. Acta Med Okayama. 1979 Aug;33(4):323-6. Acta Med Okayama. 1979. PMID: 227232
In cardiovascular diseases with potential atherosclerosis, the serum concentration of HDL cholesterol as determined by a precipitation method with dextran sulfate and Mg++ was lower while that of total cholesterol was normal or elevated. Treatment with a daily dose of 1,200 mg of …
In cardiovascular diseases with potential atherosclerosis, the serum concentration of HDL cholesterol as determined by a precipitation metho …
Effect of nicomol on high density lipoprotein (HDL) subfractions, HDL2e and HDL3e, separated by electrophoresis.
Ikeda S, Nagashima H, Taketa K, Watanabe M. Ikeda S, et al. Acta Med Okayama. 1981 Apr;35(2):143-8. doi: 10.18926/AMO/31266. Acta Med Okayama. 1981. PMID: 6456646
High density lipoprotein (HDL) fractions were separated by dextran sulfate-Mg++ from sera of 5 healthy males before and after oral administration of a daily 1200 mg dose of Nicomol (2,2,6,6-tetrakis (nicotinoyloxymethyl) cyclohexanol; Cholexamin, Kyorin Pharmaceutical Co. …
High density lipoprotein (HDL) fractions were separated by dextran sulfate-Mg++ from sera of 5 healthy males before and after oral administr …
Effects of some hypolipidemic drugs on biochemical values and on hepatic peroxisomal enzymes of normolipemic rat.
Watanabe T, Manna H, Suga T. Watanabe T, et al. J Pharmacobiodyn. 1981 Oct;4(10):743-50. doi: 10.1248/bpb1978.4.743. J Pharmacobiodyn. 1981. PMID: 6798192
Effects of vitamin B2-butyrate, nicomol, ML-236B, KF 1492 and pantethine, which are hypolipidemic drugs, on biochemical values and on hepatic peroxisomal enzymes of normolipemic rat. 1) Vitamin B2-butyrate (100 mg/kg) and nicomol (lg/Kg) increased carnitine acetyltr …
Effects of vitamin B2-butyrate, nicomol, ML-236B, KF 1492 and pantethine, which are hypolipidemic drugs, on biochemical values and on …
Protection against adriamycin (doxorubicin)-induced toxicity in mice by several clinically used drugs.
Shinozawa S, Gomita Y, Araki Y. Shinozawa S, et al. Acta Med Okayama. 1987 Feb;41(1):11-7. doi: 10.18926/AMO/31766. Acta Med Okayama. 1987. PMID: 2436440
The survival times of mice treated with the following drugs, expressed as a percent of that of the control group, were 293.6% for coenzyme Q10 (Co Q10, 2 mg/kg), 402.2% for dextran sulfate (MDS, 300 mg/kg), 121.6% for flavin adenine dinucleotide (20 mg/kg), 236.3% for adenosine t …
The survival times of mice treated with the following drugs, expressed as a percent of that of the control group, were 293.6% for coenzyme Q …
Hypolipidemic effect of NS-1 and other related drugs in rhesus monkeys.
Yoshikuni Y, Chokai S, Ozaki T, Yoshida H, Nakane M, Kuwabara K. Yoshikuni Y, et al. Atherosclerosis. 1988 Nov;74(1-2):149-56. doi: 10.1016/0021-9150(88)90201-8. Atherosclerosis. 1988. PMID: 3214474
NS-1 was more potent than clofibrate, clinofibrate, simfibrate, bezafibrate, gemfibrozil, nicomol and probucol in hypolipidemic activity in the same model. ...
NS-1 was more potent than clofibrate, clinofibrate, simfibrate, bezafibrate, gemfibrozil, nicomol and probucol in hypolipidemic activ …
Arrhythmogenic effects of acute free fatty acid mobilization on ischemic heart.
Yamazaki N, Suzuki Y, Kamikawa T, Ogawa K, Mizutani K, Kakizawa N, Yamamoto M. Yamazaki N, et al. Recent Adv Stud Cardiac Struct Metab. 1976 May 26-29;12:271-7. Recent Adv Stud Cardiac Struct Metab. 1976. PMID: 201997
These observations indicate that it may play an important role in the provocation of arrhythmia by high plasma FFA on the ischemic heart. Nicomol (2,2,6,6,-tetrakis (nicotinoyloxymethyl) cyclohexanol), an inhibitor for the rapid rise of plasma FFA, was effective in the tre …
These observations indicate that it may play an important role in the provocation of arrhythmia by high plasma FFA on the ischemic heart. …
Protective effects of various drugs on adriamycin (doxorubicin)-induced toxicity and microsomal lipid peroxidation in mice and rats.
Shinozawa S, Gomita Y, Araki Y. Shinozawa S, et al. Biol Pharm Bull. 1993 Nov;16(11):1114-7. doi: 10.1248/bpb.16.1114. Biol Pharm Bull. 1993. PMID: 8312867
The survival times of ADM-administered mice (which were injected 15 mg/kg of ADM twice) treated with the following drugs, expressed as a percent of that of the control group, were 236% for adenosine triphosphate, 224% for coenzyme Q10 (Co Q), 235% for dextran sulfate (DS), 123% f …
The survival times of ADM-administered mice (which were injected 15 mg/kg of ADM twice) treated with the following drugs, expressed as a per …
[Niceritrol decreases serum phosphate levels in chronic hemodialysis patients].
Shimoda K, Akiba T, Matsushima T, Rai T, Abe K, Hoshino M. Shimoda K, et al. Nihon Jinzo Gakkai Shi. 1998 Jan;40(1):1-7. Nihon Jinzo Gakkai Shi. 1998. PMID: 9513376 Japanese.
The aim of the present study was to assess the mechanism of the P-lowering effect of NT in comparison with nicomol (NC), another prodrug of nicotinic acid. NT (750 mg/day) or NC (600 mg/day) was given orally to 10 or 14HD patients respectively. ...
The aim of the present study was to assess the mechanism of the P-lowering effect of NT in comparison with nicomol (NC), another prod …