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Page 1
Synthesis and characterization of oxitropium bromide related substances and novel stability indicating HPLC methods.
Bellur Atici E, Ağtaş Ç, Yazar Y, Rıdvanoğlu N. Bellur Atici E, et al. J Pharm Biomed Anal. 2020 May 10;183:113145. doi: 10.1016/j.jpba.2020.113145. Epub 2020 Feb 5. J Pharm Biomed Anal. 2020. PMID: 32058292
Eur.) described two separate HPLC methods for determination of organic impurities in oxitropium bromide, a synthetic anticholinergic agent used by inhalation in the treatment of asthma and other bronchial disorders, and a potentiometric titration assay method which …
Eur.) described two separate HPLC methods for determination of organic impurities in oxitropium bromide, a synthetic anticholi …
Oxitropium bromide. Dose-response and time-response study of a new anticholinergic bronchodilator drug.
Frith PA, Jenner B, Dangerfield R, Atkinson J, Drennan C. Frith PA, et al. Chest. 1986 Feb;89(2):249-53. doi: 10.1378/chest.89.2.249. Chest. 1986. PMID: 3510822 Clinical Trial.
The efficacy and side effects of oxitropium bromide, a new anticholinergic bronchodilator drug, were tested in a double-blind placebo-control study. ...Anticholinergic effects were not seen in this group of elderly men. Oxitropium bromide therefore is …
The efficacy and side effects of oxitropium bromide, a new anticholinergic bronchodilator drug, were tested in a double-blind …
Oxitropium bromide, ipratropium bromide and fenoterol in exercise-induced asthma.
Larsson K. Larsson K. Respiration. 1982;43(1):57-63. doi: 10.1159/000194464. Respiration. 1982. PMID: 6211753 Clinical Trial.
Oxitropium bromide (Ba 253) is a new inhaled bronchodilating agent with anticholinergic properties. ...Thus, only 4 patients did benefit from ipratropium bromide, 1 patient from oxitropium bromide and 2 patients from placebo. No side effect occurred. . …
Oxitropium bromide (Ba 253) is a new inhaled bronchodilating agent with anticholinergic properties. ...Thus, only 4 patients d …
Muscarinic Receptor Antagonists.
Matera MG, Cazzola M. Matera MG, et al. Handb Exp Pharmacol. 2017;237:41-62. doi: 10.1007/164_2016_68. Handb Exp Pharmacol. 2017. PMID: 27787709 Review.
There are currently six muscarinic receptor antagonists licenced for use in the treatment of COPD, the short-acting muscarinic receptor antagonists (SAMAs) ipratropium bromide and oxitropium bromide and the long-acting muscarinic receptor antagonists (LAMAs) aclidin …
There are currently six muscarinic receptor antagonists licenced for use in the treatment of COPD, the short-acting muscarinic receptor anta …
Effects of inhalation or incubation of oxitropium bromide on diaphragm muscle contractility in mice.
Shindoh C, Shishido R, Sasaki K, Miura M. Shindoh C, et al. Allergol Int. 2011 Sep;60(3):365-72. doi: 10.2332/allergolint.10-OA-0266. Epub 2011 May 25. Allergol Int. 2011. PMID: 21593578 Free article.
METHODS: Three treatment sets, an oxitropium bromide inhalation only group, an oxitropium bromide inhalation plus endotoxin injection group (in vivo) and an oxitropium bromide incubation group (in vitro) were studied as to diaphragm muscl …
METHODS: Three treatment sets, an oxitropium bromide inhalation only group, an oxitropium bromide inhalation plu …
Effects of formoterol, salmeterol or oxitropium bromide on airway responses to salbutamol in COPD.
Cazzola M, Di Perna F, Noschese P, Vinciguerra A, Calderaro F, Girbino G, Matera MG. Cazzola M, et al. Eur Respir J. 1998 Jun;11(6):1337-41. doi: 10.1183/09031936.98.11061337. Eur Respir J. 1998. PMID: 9657576 Free article. Clinical Trial.
We examined whether a pretreatment with formoterol, oxitropium bromide, or salmeterol might modify the dose-response curves to inhaled salbutamol in patients with stable and partially reversible chronic obstructive pulmonary disease (COPD). ...Dose increments were g …
We examined whether a pretreatment with formoterol, oxitropium bromide, or salmeterol might modify the dose-response curves to …
Oxitropium bromide improves exercise performance in patients with COPD.
Ikeda A, Nishimura K, Koyama H, Sugiura N, Izumi T. Ikeda A, et al. Chest. 1994 Dec;106(6):1740-5. doi: 10.1378/chest.106.6.1740. Chest. 1994. PMID: 7988193 Clinical Trial.
All the patients were studied by symptom-limited progressive cycle ergometry before and 90 min after the inhalation of either oxitropium bromide, 800 micrograms, or an identical placebo. Spirometry was assessed before and after each exercise test. ...There was a sig …
All the patients were studied by symptom-limited progressive cycle ergometry before and 90 min after the inhalation of either oxitropium …
Incremental benefit of adding oxitropium bromide to formoterol in patients with stable COPD.
Cazzola M, Di Perna F, Califano C, Vinciguerra A, D'Amato M. Cazzola M, et al. Pulm Pharmacol Ther. 1999;12(4):267-71. doi: 10.1006/pupt.1999.0208. Pulm Pharmacol Ther. 1999. PMID: 10501652 Clinical Trial.
On each of 4 study days patients inhaled both drugs separated by 180 min in alternate sequence, with formoterol being administered in two doses (formoterol 12 microg + oxitropium bromide 200 microg; oxitropium bromide 200 microg + formoterol 12 microg; …
On each of 4 study days patients inhaled both drugs separated by 180 min in alternate sequence, with formoterol being administered in two do …
Oxitropium bromide: an acute dose response study of a new anticholinergic drug in combination with fenoterol in asthma and chronic bronchitis.
Bryant DH, Rogers P. Bryant DH, et al. Pulm Pharmacol. 1990;3(2):55-8. doi: 10.1016/0952-0600(90)90032-e. Pulm Pharmacol. 1990. PMID: 2135210 Clinical Trial.
The peak bronchodilator response to oxitropium bromide of the patients with chronic bronchitis was equivalent to the fenoterol response while, in the patients with asthma, the response to oxitropium bromide was approximately 30% of the response to feno …
The peak bronchodilator response to oxitropium bromide of the patients with chronic bronchitis was equivalent to the fenoterol …
Bronchodilator effects of oxitropium bromide, fenoterol, and their combination in normal subjects.
Fujimura M, Kamio Y, Matsuda T, Hashimoto T. Fujimura M, et al. Clin Auton Res. 1993 Feb;3(1):31-5. doi: 10.1007/BF01819140. Clin Auton Res. 1993. PMID: 8477178 Clinical Trial.
Oxitropium bromide is a quaternary anticholinergic compound based on the scopolamine molecule instead of atropine. ...The group mean percentage increase in the PEF25-time course curve was significantly greater after treatment with the combination than with placebo ( …
Oxitropium bromide is a quaternary anticholinergic compound based on the scopolamine molecule instead of atropine. ...The grou …
150 results