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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 6
1980 3
1981 8
1982 9
1983 8
1984 9
1985 21
1986 24
1987 30
1988 46
1989 50
1990 81
1991 74
1992 90
1993 110
1994 106
1995 107
1996 130
1997 138
1998 104
1999 129
2000 135
2001 144
2002 125
2003 138
2004 108
2005 112
2006 121
2007 124
2008 114
2009 122
2010 109
2011 99
2012 93
2013 110
2014 89
2015 101
2016 91
2017 77
2018 70
2019 77
2020 59
2021 90
2022 72
2023 69
2024 24

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3,489 results

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Page 1
Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective.
Collett-Solberg PF, Ambler G, Backeljauw PF, Bidlingmaier M, Biller BMK, Boguszewski MCS, Cheung PT, Choong CSY, Cohen LE, Cohen P, Dauber A, Deal CL, Gong C, Hasegawa Y, Hoffman AR, Hofman PL, Horikawa R, Jorge AAL, Juul A, Kamenický P, Khadilkar V, Kopchick JJ, Kriström B, Lopes MLA, Luo X, Miller BS, Misra M, Netchine I, Radovick S, Ranke MB, Rogol AD, Rosenfeld RG, Saenger P, Wit JM, Woelfle J. Collett-Solberg PF, et al. Horm Res Paediatr. 2019;92(1):1-14. doi: 10.1159/000502231. Epub 2019 Sep 12. Horm Res Paediatr. 2019. PMID: 31514194 Free PMC article. Review.
While some long-standing topics of controversy continue to generate debate, including in whom, and how, to perform and interpret growth hormone stimulation tests, new research areas are changing the clinical landscape, such as the genetics of short stature, s …
While some long-standing topics of controversy continue to generate debate, including in whom, and how, to perform and interpret growth …
Growth hormone - past, present and future.
Ranke MB, Wit JM. Ranke MB, et al. Nat Rev Endocrinol. 2018 May;14(5):285-300. doi: 10.1038/nrendo.2018.22. Epub 2018 Mar 16. Nat Rev Endocrinol. 2018. PMID: 29546874 Review.
Growth hormone (GH) research and its clinical application for the treatment of growth disorders span more than a century. ...The following era (1985 to present) of molecular genetics, recombinant technology and the generation of genetically …
Growth hormone (GH) research and its clinical application for the treatment of growth disorders span more than a centur …
Should Skeletal Maturation Be Manipulated for Extra Height Gain?
Wit JM. Wit JM. Front Endocrinol (Lausanne). 2021 Dec 16;12:812196. doi: 10.3389/fendo.2021.812196. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34975773 Free PMC article. Review.
Skeletal maturation can be delayed by reducing the exposure to estrogens, either by halting pubertal development through administering a GnRH analogue (GnRHa), or by blocking the conversion of androgens to estrogens through an aromatase inhibitor (AI). These agents have been inve …
Skeletal maturation can be delayed by reducing the exposure to estrogens, either by halting pubertal development through administering a GnR …
Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort.
Maghnie M, Ranke MB, Geffner ME, Vlachopapadopoulou E, Ibáñez L, Carlsson M, Cutfield W, Rooman R, Gomez R, Wajnrajch MP, Linglart A, Stawerska R, Clayton PE, Darendeliler F, Hokken-Koelega ACS, Horikawa R, Tanaka T, Dörr HG, Albertsson-Wikland K, Polak M, Grimberg A. Maghnie M, et al. J Clin Endocrinol Metab. 2022 Nov 25;107(12):3287-3301. doi: 10.1210/clinem/dgac517. J Clin Endocrinol Metab. 2022. PMID: 36102184 Free PMC article.
CONTEXT: The Kabi/Pfizer International Growth Database (KIGS) is a large, international database (1987-2012) of children treated with recombinant human growth hormone (rhGH) in real-world settings. ...METHODS: Data were collected by investigator …
CONTEXT: The Kabi/Pfizer International Growth Database (KIGS) is a large, international database (1987-2012) of children treated with …
Solubilization and refolding of bacterial inclusion body proteins.
Singh SM, Panda AK. Singh SM, et al. J Biosci Bioeng. 2005 Apr;99(4):303-10. doi: 10.1263/jbb.99.303. J Biosci Bioeng. 2005. PMID: 16233795 Review.
Refolding of inclusion body proteins into bioactive forms is cumbersome, results in poor recovery and accounts for the major cost in production of recombinant proteins from E. coli. With new information available on the structure and function of protein aggregates in bacte …
Refolding of inclusion body proteins into bioactive forms is cumbersome, results in poor recovery and accounts for the major cost in product …
GrowthHormone Research Society workshop summary: consensus guidelines for recombinant human growth hormone therapy in Prader-Willi syndrome.
Deal CL, Tony M, Höybye C, Allen DB, Tauber M, Christiansen JS; 2011 Growth Hormone in Prader-Willi Syndrome Clinical Care Guidelines Workshop Participants. Deal CL, et al. J Clin Endocrinol Metab. 2013 Jun;98(6):E1072-87. doi: 10.1210/jc.2012-3888. Epub 2013 Mar 29. J Clin Endocrinol Metab. 2013. PMID: 23543664 Free PMC article. Review.
CONTEXT: Recombinant human GH (rhGH) therapy in Prader-Willi syndrome (PWS) has been used by the medical community and advocated by parental support groups since its approval in the United States in 2000 and in Europe in 2001. ...CONCLUSIONS: Following a multidiscip …
CONTEXT: Recombinant human GH (rhGH) therapy in Prader-Willi syndrome (PWS) has been used by the medical community and advocat …
Clinical Characteristics of Short-Stature Patients With Collagen Gene Mutation and the Therapeutic Response to rhGH.
Chen M, Miao H, Liang H, Ke X, Yang H, Gong F, Wang L, Duan L, Chen S, Pan H, Zhu H. Chen M, et al. Front Endocrinol (Lausanne). 2022 Feb 16;13:820001. doi: 10.3389/fendo.2022.820001. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35250876 Free PMC article.
CONTEXT: Clinical genetic evaluation has been demonstrated as an important tool to elucidate the causes of growth disorders. ...Etiological diagnosis of skeletal abnormality-related short stature is challenging, and less is known about recombinant human …
CONTEXT: Clinical genetic evaluation has been demonstrated as an important tool to elucidate the causes of growth disorders. . …
Short stature related to Growth Hormone Insensitivity (GHI) in childhood.
Mastromauro C, Giannini C, Chiarelli F. Mastromauro C, et al. Front Endocrinol (Lausanne). 2023 Mar 15;14:1141039. doi: 10.3389/fendo.2023.1141039. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37008935 Free PMC article. Review.
The best growth determinant system during each period of life is represented by the growth hormone-insulin-like growth factor axis (GH-IGF), even if several other factors are involved in normal growth. Within the broad spectrum of growth …
The best growth determinant system during each period of life is represented by the growth hormone-insulin-like grow …
Inside the Noonan "universe": Literature review on growth, GH/IGF axis and rhGH treatment: Facts and concerns.
Stagi S, Ferrari V, Ferrari M, Priolo M, Tartaglia M. Stagi S, et al. Front Endocrinol (Lausanne). 2022 Aug 18;13:951331. doi: 10.3389/fendo.2022.951331. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36060964 Free PMC article. Review.
NS is caused by germline pathogenic variants in genes coding proteins with a role in the RAS/mitogen-activated protein kinase signaling pathway, and it is typically associated with substantial genetic and clinical complexity and variability. Short stature is a cardinal fea …
NS is caused by germline pathogenic variants in genes coding proteins with a role in the RAS/mitogen-activated protein kinase signaling path …
Growth hormone insensitivity: diagnostic and therapeutic approaches.
Kurtoğlu S, Hatipoglu N. Kurtoğlu S, et al. J Endocrinol Invest. 2016 Jan;39(1):19-28. doi: 10.1007/s40618-015-0327-2. Epub 2015 Jun 11. J Endocrinol Invest. 2016. PMID: 26062520 Review.
INTRODUCTION: Growth hormone resistance defines several genetic (primary) and acquired (secondary) pathologies that result in completely or partially interrupted activity of growth hormone. An archetypal disease of this group is the Laron-type d …
INTRODUCTION: Growth hormone resistance defines several genetic (primary) and acquired (secondary) pathologies that res …
3,489 results