Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1960 11
1961 12
1962 116
1963 165
1964 129
1965 97
1966 97
1967 89
1968 81
1969 63
1970 54
1971 66
1972 60
1973 57
1974 42
1975 36
1976 37
1977 42
1978 28
1979 28
1980 24
1981 36
1982 33
1983 43
1984 36
1985 39
1986 35
1987 24
1988 41
1989 39
1990 50
1991 30
1992 51
1993 37
1994 58
1995 91
1996 94
1997 102
1998 123
1999 144
2000 191
2001 246
2002 326
2003 352
2004 342
2005 380
2006 449
2007 492
2008 510
2009 540
2010 583
2011 614
2012 692
2013 680
2014 671
2015 658
2016 681
2017 639
2018 515
2019 500
2020 545
2021 494
2022 394
2023 332
2024 170

Text availability

Article attribute

Article type

Publication date

Search Results

13,046 results

Results by year

Filters applied: . Clear all
Page 1
Thalidomide.
Franks ME, Macpherson GR, Figg WD. Franks ME, et al. Lancet. 2004 May 29;363(9423):1802-11. doi: 10.1016/S0140-6736(04)16308-3. Lancet. 2004. PMID: 15172781 Review.
Despite its history as a human teratogen, thalidomide is emerging as a treatment for cancer and inflammatory diseases. Although the evolution of its clinical application could not have been predicted from the tragedy associated with its misuse in the past, its history serv …
Despite its history as a human teratogen, thalidomide is emerging as a treatment for cancer and inflammatory diseases. Although the e …
The role of thalidomide in dermatology.
Hussain K, Patel P, Roberts N. Hussain K, et al. Clin Exp Dermatol. 2022 Apr;47(4):667-674. doi: 10.1111/ced.15019. Epub 2021 Dec 19. Clin Exp Dermatol. 2022. PMID: 34779533 Review.
Thalidomide is a medication that has been in existence for over half a century, and has proven to be useful and effective in severe dermatological conditions. ...In this review, we look at the background and mechanism of action of thalidomide, provide an overview of …
Thalidomide is a medication that has been in existence for over half a century, and has proven to be useful and effective in severe d …
The thalidomide disaster, lessons from the past.
Ridings JE. Ridings JE. Methods Mol Biol. 2013;947:575-86. doi: 10.1007/978-1-62703-131-8_36. Methods Mol Biol. 2013. PMID: 23138926
It is close to 60 years since thalidomide was created by the German company, Chemie-Grunenthal, and launched as "Contergan." ...The full story of thalidomide was told by the Sunday Times in "Suffer The Children" (Kingsley et al., Suffer the children: the story of …
It is close to 60 years since thalidomide was created by the German company, Chemie-Grunenthal, and launched as "Contergan." ...The f …
From Thalidomide to Rational Molecular Glue Design for Targeted Protein Degradation.
Oleinikovas V, Gainza P, Ryckmans T, Fasching B, Thomä NH. Oleinikovas V, et al. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:291-312. doi: 10.1146/annurev-pharmtox-022123-104147. Epub 2023 Aug 16. Annu Rev Pharmacol Toxicol. 2024. PMID: 37585660 Free article. Review.
Thalidomide and its derivatives are powerful cancer therapeutics that are among the best-understood molecular glue degraders (MGDs). ...
Thalidomide and its derivatives are powerful cancer therapeutics that are among the best-understood molecular glue degraders (MGDs). …
Molecular mechanisms of thalidomide and its derivatives.
Ito T, Handa H. Ito T, et al. Proc Jpn Acad Ser B Phys Biol Sci. 2020;96(6):189-203. doi: 10.2183/pjab.96.016. Proc Jpn Acad Ser B Phys Biol Sci. 2020. PMID: 32522938 Free PMC article.
Although the molecular mechanisms of thalidomide and its derivatives remained poorly understood until recently, we identified cereblon (CRBN), a primary direct target of thalidomide, using ferrite glycidyl methacrylate (FG) beads. CRBN is a ligand-dependent substrat …
Although the molecular mechanisms of thalidomide and its derivatives remained poorly understood until recently, we identified cereblo …
[Thalidomide embryopathy 60 years].
Passarge E. Passarge E. Dtsch Med Wochenschr. 2022 Dec;147(24-25):1635-1638. doi: 10.1055/a-1951-0792. Epub 2022 Dec 5. Dtsch Med Wochenschr. 2022. PMID: 36470274 Review. German.
This review describes the recognition and effects of thalidomide as a potent teratogenic agent sixty years ago. A systematic analysis revealed a broad spectrum of multiple congenital birth defects involving many organ systems. ...Today about 2400 adults live with chronic l …
This review describes the recognition and effects of thalidomide as a potent teratogenic agent sixty years ago. A systematic analysis …
Thalidomide in dermatology.
Wines NY, Cooper AJ, Wines MP. Wines NY, et al. Australas J Dermatol. 2002 Nov;43(4):229-38; quiz 239-40. doi: 10.1046/j.1440-0960.2002.00608.x. Australas J Dermatol. 2002. PMID: 12423428 Review.
Thalidomide is an effective agent to treat over 25 seemingly unrelated dermatological conditions that have an inflammatory or autoimmune basis. ...A review of the therapeutic indications for thalidomide in dermatology as well as the mechanisms of action and side-eff …
Thalidomide is an effective agent to treat over 25 seemingly unrelated dermatological conditions that have an inflammatory or autoimm …
Thalidomide for the treatment of chronic refractory pruritus.
Sharma D, Kwatra SG. Sharma D, et al. J Am Acad Dermatol. 2016 Feb;74(2):363-9. doi: 10.1016/j.jaad.2015.09.039. Epub 2015 Nov 11. J Am Acad Dermatol. 2016. PMID: 26577510 Review.
Because of variations in study design and evaluation of antipruritic effect, it is difficult to fully understand thalidomide's role based on the evidence described to date in the medical literature. In this review, we provide an overview of the reported findings and …
Because of variations in study design and evaluation of antipruritic effect, it is difficult to fully understand thalidomide's …
Efficacy of Thalidomide in Discoid Lupus Erythematosus: Insights into the Molecular Mechanisms.
Domingo S, Solé C, Moliné T, Ferrer B, Ordi-Ros J, Cortés-Hernández J. Domingo S, et al. Dermatology. 2020;236(5):467-476. doi: 10.1159/000508672. Epub 2020 Jul 13. Dermatology. 2020. PMID: 32659758 Free article. Review.
SUMMARY: Thalidomide's efficacy in DLE patients is significant, with 80-90% reaching clinical remission according to different studies. However, thalidomide's use is still limited by serious adverse effects such as teratogenicity, neurotoxicity, and th …
SUMMARY: Thalidomide's efficacy in DLE patients is significant, with 80-90% reaching clinical remission according to different …
13,046 results
You have reached the last available page of results. Please see the User Guide for more information.

Searches related to "thalidomide"