Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2010 1
2011 1
2012 2
2013 2
2014 3
2015 1
2016 1
2018 1
2020 2
2021 2
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

14 results

Results by year

Filters applied: . Clear all
Page 1
Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan, in healthy volunteers.
Lee J, Lee H, Jang K, Lim KS, Shin D, Yu KS. Lee J, et al. Drug Des Devel Ther. 2014 Oct 8;8:1781-8. doi: 10.2147/DDDT.S68574. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25336921 Free PMC article. Clinical Trial.
PURPOSE: Although cilnidipine and valsartan are widely coadministered to patients with hypertension, their drug-drug interaction potential has not been investigated. ...Likewise, cilnidipine did not affect the PK of valsartan; the geometr …
PURPOSE: Although cilnidipine and valsartan are widely coadministered to patients with hypertension, their drug-drug
Comparative effects of valsartan plus cilnidipine or hydrochlorothiazide on nocturnal home blood pressure.
Fujiwara T, Hoshide S, Tomitani N, Kanegae H, Kario K. Fujiwara T, et al. J Clin Hypertens (Greenwich). 2021 Mar;23(3):687-691. doi: 10.1111/jch.14199. Epub 2021 Jan 26. J Clin Hypertens (Greenwich). 2021. PMID: 33497537 Free PMC article. Clinical Trial.
We tested our hypothesis that, in hypertensive patients with higher nocturnal home systolic blood pressure (HSBP) at baseline, a valsartan/cilnidipine (80/10 mg) combination would reduce nocturnal HSBP more markedly than a valsartan/hydrochlorothiazide …
We tested our hypothesis that, in hypertensive patients with higher nocturnal home systolic blood pressure (HSBP) at baseline, a valsarta
Powerful vascular protection by combining cilnidipine with valsartan in stroke-prone, spontaneously hypertensive rats.
Takai S, Jin D, Aritomi S, Niinuma K, Miyazaki M. Takai S, et al. Hypertens Res. 2013 Apr;36(4):342-8. doi: 10.1038/hr.2012.187. Epub 2012 Nov 29. Hypertens Res. 2013. PMID: 23190689 Free PMC article.
Compared with the valsartan-treated group, the positive areas for 4-hydroxy-2-nonenal were significantly lower only in the valsartan+cilnidipine-treated group. ...Thus, valsartan and cilnidipine combination therapy might have a powerful p …
Compared with the valsartan-treated group, the positive areas for 4-hydroxy-2-nonenal were significantly lower only in the valsart
Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats.
Nagasawa K, Takahashi K, Matsuura N, Takatsu M, Hattori T, Watanabe S, Harada E, Niinuma K, Murohara T, Nagata K. Nagasawa K, et al. Hypertens Res. 2015 Jan;38(1):39-47. doi: 10.1038/hr.2014.136. Epub 2014 Sep 11. Hypertens Res. 2015. PMID: 25209105
We have now compared the effects of the ARB valsartan combined with cilnidipine or amlodipine on cardiac pathophysiology in DS rats. DS rats fed a high-salt diet from 6 weeks of age were treated with vehicle, valsartan alone (10 mg kg(-1) per day), or …
We have now compared the effects of the ARB valsartan combined with cilnidipine or amlodipine on cardiac pathophysiolog …
Comparison between valsartan and valsartan plus cilnidipine in type II diabetics with normo- and microalbuminuria.
Katayama K, Nomura S, Ishikawa H, Murata T, Koyabu S, Nakano T. Katayama K, et al. Kidney Int. 2006 Jul;70(1):151-6. doi: 10.1038/sj.ki.5000349. Epub 2006 May 17. Kidney Int. 2006. PMID: 16710356 Free article. Clinical Trial.
The objective of this trial was to evaluate the effect of reducing albuminuria in type II diabetic patients with a combination therapy consisting of valsartan plus cilnidipine versus monotherapy with valsartan. ...After 1 year, the albumin/creatinine r …
The objective of this trial was to evaluate the effect of reducing albuminuria in type II diabetic patients with a combination therap …
Comparative effects of valsartan plus either cilnidipine or hydrochlorothiazide on home morning blood pressure surge evaluated by information and communication technology-based nocturnal home blood pressure monitoring.
Fujiwara T, Tomitani N, Kanegae H, Kario K. Fujiwara T, et al. J Clin Hypertens (Greenwich). 2018 Jan;20(1):159-167. doi: 10.1111/jch.13154. Epub 2018 Jan 5. J Clin Hypertens (Greenwich). 2018. PMID: 29316213 Free PMC article. Clinical Trial.
The authors tested the hypothesis that a valsartan/cilnidipine combination would suppress the home morning blood pressure (BP) surge (HMBPS) more effectively than a valsartan/hydrochlorothiazide combination in patients with morning hypertension, …
The authors tested the hypothesis that a valsartan/cilnidipine combination would suppress the home morning blood pressu …
A post-marketing survey evaluating the safety and efficacy of a fixed-dose single-pill combination of cilnidipine and valsartan in patients with hypertension: Real-world JSH 2014 and 2019 implementations.
Matsuda S, Nagahama S, Kurose Y, Wakabayashi M, Sugii H, Teshima T, Suzuki N, Kario K. Matsuda S, et al. Clin Exp Hypertens. 2020 Aug 17;42(6):502-511. doi: 10.1080/10641963.2020.1714641. Epub 2020 Jan 22. Clin Exp Hypertens. 2020. PMID: 31964180
METHODS: : The home blood pressure control by a single-pill combination of cilnidipine and valsartan (HOPE-Combi) survey sought to evaluate the safety and efficacy of cilnidipine 10 mg/valsartan 80 mg single-pill combination (SPC of Cil/V …
METHODS: : The home blood pressure control by a single-pill combination of cilnidipine and valsartan (HOPE-Combi) surve …
Single-pill combination of cilnidipine, an L-/N-type calcium channel blocker, and valsartan effectively reduces home pulse pressure in patients with uncontrolled hypertension and sympathetic hyperactivity: The HOPE-Combi survey.
Kario K, Matsuda S, Nagahama S, Kurose Y, Sugii H, Teshima T, Suzuki N. Kario K, et al. J Clin Hypertens (Greenwich). 2020 Mar;22(3):457-464. doi: 10.1111/jch.13771. J Clin Hypertens (Greenwich). 2020. PMID: 32311215 Free PMC article.
The home blood pressure (BP) control by a single-pill combination of cilnidipine (an L-/N-type calcium channel blocker; CCB) and valsartan (HOPE-Combi) survey is a multicenter, post-marketing, prospective observational study of a single-pill combination
The home blood pressure (BP) control by a single-pill combination of cilnidipine (an L-/N-type calcium channel blocker; CCB) a …
Single-pill combination of cilnidipine, an l-/n-type calcium channel blocker, and valsartan reduces the day-by-day variability of morning home systolic blood pressure in patients with treated hypertension: A sub-analysis of the HOPE-combi survey.
Kario K, Matsuda S, Nagahama S, Kurose Y, Sugii H, Teshima T, Suzuki N. Kario K, et al. J Clin Hypertens (Greenwich). 2021 Feb;23(2):392-397. doi: 10.1111/jch.14178. Epub 2021 Jan 17. J Clin Hypertens (Greenwich). 2021. PMID: 33455076 Free PMC article.
We examined the effects of a fixed-dose single-pill combination of cilnidipine (10 mg), an L-/N-type calcium channel blocker, and valsartan (80 mg) (SPC of Cil/Val) on the day-by-day variability of morning home systolic blood pressure (MHSBP) in 616 patients …
We examined the effects of a fixed-dose single-pill combination of cilnidipine (10 mg), an L-/N-type calcium channel blocker, …
Effects of an N-type calcium antagonist on angiotensin II-renin feedback.
Aritomi S, Niinuma K, Ogawa T, Konda T, Nitta K. Aritomi S, et al. Am J Nephrol. 2011;33(2):168-75. doi: 10.1159/000323969. Epub 2011 Feb 4. Am J Nephrol. 2011. PMID: 21293118
Combined administration of cilnidipine, but not amlodipine, and valsartan significantly reduced the noradrenaline content in the renal cortex. CONCLUSIONS: The results of this study suggest that the suppressive effect of cilnidipine on the valsartan
Combined administration of cilnidipine, but not amlodipine, and valsartan significantly reduced the noradrenaline conte
14 results