Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2006 3
2007 10
2008 18
2009 16
2010 9
2011 10
2012 14
2013 21
2014 25
2015 18
2016 18
2017 14
2018 5
2019 10
2020 12
2021 12
2022 6
2023 4
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

203 results

Results by year

Filters applied: . Clear all
Page 1
Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial.
Matthews DR, Paldánius PM, Proot P, Chiang Y, Stumvoll M, Del Prato S; VERIFY study group. Matthews DR, et al. Lancet. 2019 Oct 26;394(10208):1519-1529. doi: 10.1016/S0140-6736(19)32131-2. Epub 2019 Sep 18. Lancet. 2019. PMID: 31542292 Clinical Trial.
METHODS: Vildagliptin Efficacy in combination with metfoRmIn For earlY treatment of type 2 diabetes (VERIFY) was a randomised, double-blind, parallel-group study of newly diagnosed patients with type 2 diabetes conducted in 254 centres across 34 countries. .. …
METHODS: Vildagliptin Efficacy in combination with metfoRmIn For earlY treatment of type 2 diabetes (VERIFY) was a rand …
Drug evaluation: vildagliptin-metformin single-tablet combination.
Tahrani AA, Piya MK, Barnett AH. Tahrani AA, et al. Adv Ther. 2009 Feb;26(2):138-54. doi: 10.1007/s12325-009-0010-0. Epub 2009 Mar 19. Adv Ther. 2009. PMID: 19288260 Review.
The single-tablet combination of vildagliptin and metformin addresses key defects of type 2 diabetes for improved glycemic control. ...In active-controlled trials, the vildagliptin-metformin combination has been shown to produce equivalen …
The single-tablet combination of vildagliptin and metformin addresses key defects of type 2 diabetes for improved glyce …
Vildagliptin.
Henness S, Keam SJ. Henness S, et al. Drugs. 2006;66(15):1989-2001; discussion 2002-4. doi: 10.2165/00003495-200666150-00007. Drugs. 2006. PMID: 17100408 Review.
Vildagliptin also showed efficacy in reducing HbA(1c) levels in patients with type 2 diabetes when used in combination with metformin, pioglitazone or insulin. Vildagliptin was generally well tolerated when administered alone or in combination w …
Vildagliptin also showed efficacy in reducing HbA(1c) levels in patients with type 2 diabetes when used in combination with …
Bioequivalence Studies of New Generic Formulations of Vildagliptin and Fixed-Drug Combination of Vildagliptin and Metformin Versus Respective Originator Products in Healthy Volunteers.
Schnaars Y, Gaikwad S, Gottwald-Hostalek U, Klingberg U, Vadla HKC, Prathap VR. Schnaars Y, et al. Diabetes Ther. 2022 Jun;13(6):1215-1229. doi: 10.1007/s13300-022-01269-1. Epub 2022 May 11. Diabetes Ther. 2022. PMID: 35543870 Free PMC article.
Two new generic products, vildagliptin and its fixed-drug combination (FDC) with metformin, were tested for bioequivalence versus the approved originator reference products (Galvus and Eucreas). ...No severe or serious AEs occurred. CONCLUSIONS: The ne …
Two new generic products, vildagliptin and its fixed-drug combination (FDC) with metformin, were tested for bioe …
Combined vildagliptin and metformin exert better cardioprotection than monotherapy against ischemia-reperfusion injury in obese-insulin resistant rats.
Apaijai N, Chinda K, Palee S, Chattipakorn S, Chattipakorn N. Apaijai N, et al. PLoS One. 2014 Jul 18;9(7):e102374. doi: 10.1371/journal.pone.0102374. eCollection 2014. PLoS One. 2014. PMID: 25036861 Free PMC article.
Rats in each diet group were divided into 4 subgroups to receive vildagliptin, metformin, combined vildagliptin and metformin, or saline for 21 days. ...Rats developed insulin resistance after 12 weeks of HFD consumption. Vildagliptin, …
Rats in each diet group were divided into 4 subgroups to receive vildagliptin, metformin, combined vildagliptin …
Effects of Anti-Diabetic Drugs on Fracture Risk: A Systematic Review and Network Meta-Analysis.
Zhang YS, Zheng YD, Yuan Y, Chen SC, Xie BC. Zhang YS, et al. Front Endocrinol (Lausanne). 2021 Oct 14;12:735824. doi: 10.3389/fendo.2021.735824. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34721294 Free PMC article.
Risk ratio (RR) with its 95% confidence interval (CI) was calculated by combining data for the fracture effects of anti-diabetic drugs, including sodium-glucose co-transporter 2 (SGLT2) inhibitors, dipeptidyl peptidase-4 (DPP-4) inhibitors, glucagon-like peptide-1 (GLP-1) …
Risk ratio (RR) with its 95% confidence interval (CI) was calculated by combining data for the fracture effects of anti-diabetic drug …
Efficacy of a Combination of Metformin and Vildagliptin in Comparison to Metformin Alone in Type 2 Diabetes Mellitus: A Multicentre, Retrospective, Real-World Evidence Study.
Mohan V, Zargar A, Chawla M, Joshi A, Ayyagari U, Sethi B, Gaurav K, Patted URH, Bhagat SV, Mane AI. Mohan V, et al. Diabetes Metab Syndr Obes. 2021 Jun 29;14:2925-2933. doi: 10.2147/DMSO.S315227. eCollection 2021. Diabetes Metab Syndr Obes. 2021. PMID: 34234490 Free PMC article.
Given the limitation of the traditional stepwise intensification strategy, early combination therapy can be an effective approach. Therefore, this study aims to assess the real-world efficacy of a combination of metformin and vildagliptin in comparison …
Given the limitation of the traditional stepwise intensification strategy, early combination therapy can be an effective approach. Th …
Initial combination therapy with vildagliptin plus metformin in drug-naive patients with T2DM: a 24-week real-life study from Asia.
Chawla M, Kim TH, Mirasol RC, Faruque P, Cooke K, Hours-Zesiger P, Shete A. Chawla M, et al. Curr Med Res Opin. 2018 Sep;34(9):1605-1611. doi: 10.1080/03007995.2018.1476333. Epub 2018 Jun 12. Curr Med Res Opin. 2018. PMID: 29764225
AIMS: To assess the effectiveness and safety of vildagliptin/metformin initial combination therapy in drug-naive patients with type 2 diabetes mellitus (T2DM). ...There were no serious adverse events or deaths. CONCLUSIONS: Overall, in a relatively you …
AIMS: To assess the effectiveness and safety of vildagliptin/metformin initial combination therapy in drug-naive …
Pharmacokinetics and Bioequivalence of a Generic Fixed-Dose Combination Tablet of Metformin Hydrochloride/Vildagliptin Versus a Branded Product in Healthy Chinese Subjects Under Fed and Fasting Conditions.
Ye L, Li B, Ling N, Gao Y, Tao X, Cai S, Wang Y, Chen S, Wang F. Ye L, et al. Clin Pharmacol Drug Dev. 2022 Jan;11(1):63-70. doi: 10.1002/cpdd.992. Epub 2021 Jul 17. Clin Pharmacol Drug Dev. 2022. PMID: 34273258 Clinical Trial.
The purpose of this study was to compare the bioequivalence and safety of test and reference preparations of fixed-dose combination tablets of metformin hydrochloride/vildagliptin 850 mg/50 mg in healthy volunteers under fasting and fed conditions for …
The purpose of this study was to compare the bioequivalence and safety of test and reference preparations of fixed-dose combination t …
Efficacy and safety of combination therapy with vildagliptin and metformin vs. metformin monotherapy for Type 2 Diabetes Mellitus therapy: a meta-analysis.
Ding Y, Liu Y, Qu Y, Lin M, Dong F, Li Y, Cao L, Lin S. Ding Y, et al. Eur Rev Med Pharmacol Sci. 2022 Apr;26(8):2802-2817. doi: 10.26355/eurrev_202204_28611. Eur Rev Med Pharmacol Sci. 2022. PMID: 35503625 Free article.
CONCLUSIONS: Compared with metformin, vildagliptin combined with metformin could significantly reduce FPG, HbA1c and body weight. When the dose of metformin in the combination group of vildagliptin and metformin is 1500mg/d, …
CONCLUSIONS: Compared with metformin, vildagliptin combined with metformin could significantly reduce FPG, HbA1c …
203 results