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Page 1
Opioids.
[No authors listed] [No authors listed] 2020 Nov 24. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2020 Nov 24. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643200 Free Books & Documents. Review.
The natural alkaloids are also referred to as opiates and include morphine and codeine. Synthetic derivatives include heroin, fentanyl, hydromorphone, methadone, buprenorphine and others. The opioids are highly potent and effective analgesics, but most have a high potentia …
The natural alkaloids are also referred to as opiates and include morphine and codeine. Synthetic derivatives include heroin, fentanyl, h …
Reducing Opioid Use for Chronic Pain With a Group-Based Intervention: A Randomized Clinical Trial.
Sandhu HK, Booth K, Furlan AD, Shaw J, Carnes D, Taylor SJC, Abraham C, Alleyne S, Balasubramanian S, Betteley L, Haywood KL, Iglesias-Urrutia CP, Krishnan S, Lall R, Manca A, Mistry D, Newton S, Noyes J, Nichols V, Padfield E, Rahman A, Seers K, Tang NKY, Tysall C, Eldabe S, Underwood M. Sandhu HK, et al. JAMA. 2023 May 23;329(20):1745-1756. doi: 10.1001/jama.2023.6454. JAMA. 2023. PMID: 37219554 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: Multicentered, randomized clinical trial of 608 adults taking strong opioids (buprenorphine, dipipanone, morphine, diamorphine, fentanyl, hydromorphone, methadone, oxycodone, papaveretum, pentazocine, pethidine, tapentadol, and tramadol) …
DESIGN, SETTING, AND PARTICIPANTS: Multicentered, randomized clinical trial of 608 adults taking strong opioids (buprenorphine, dipipanone, …
Prescription of Controlled Substances: Benefits and Risks.
Preuss CV, Kalava A, King KC. Preuss CV, et al. 2023 Apr 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Apr 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 30726003 Free Books & Documents.
Controlled Substance Act In the United States, the Comprehensive Drug Abuse Prevention and Control Act was passed in 1970, and it included the Controlled Substance Act. ...When a partial fill occurs, it is treated in the same manner and with the same rules as a refi …
Controlled Substance Act In the United States, the Comprehensive Drug Abuse Prevention and Control Act was passed in 1970, and …
Trends in abuse and misuse of prescription opioids among older adults.
West NA, Severtson SG, Green JL, Dart RC. West NA, et al. Drug Alcohol Depend. 2015 Apr 1;149:117-21. doi: 10.1016/j.drugalcdep.2015.01.027. Epub 2015 Jan 31. Drug Alcohol Depend. 2015. PMID: 25678441
METHODS: Trend analysis using linear regression models was used to analyze 184,136 cases and 1149 deaths associated with abuse and misuse of the prescription opioids oxycodone, fentanyl, hydrocodone, morphine, oxymorphone, hydromorphone, methadone, buprenorphine, tr …
METHODS: Trend analysis using linear regression models was used to analyze 184,136 cases and 1149 deaths associated with abuse and mi …
Safety profile of injectable hydromorphone and diacetylmorphine for long-term severe opioid use disorder.
Oviedo-Joekes E, Brissette S, MacDonald S, Guh D, Marchand K, Jutha S, Harrison S, Janmohamed A, Zhang DZ, Anis AH, Krausz M, Marsh DC, Schechter MT. Oviedo-Joekes E, et al. Drug Alcohol Depend. 2017 Jul 1;176:55-62. doi: 10.1016/j.drugalcdep.2017.02.021. Epub 2017 May 10. Drug Alcohol Depend. 2017. PMID: 28521199 Clinical Trial.
AIMS: To review the safety profile of injectable hydromorphone and diacetylmorphine and explore if adverse events (AEs) or serious adverse events (SAEs) were associated with dose and patterns of attendance. METHODS: This was a non-inferiority randomized double-blind contro …
AIMS: To review the safety profile of injectable hydromorphone and diacetylmorphine and explore if adverse events (AEs) or serious ad …
Evaluation of an emergency safe supply drugs and managed alcohol program in COVID-19 isolation hotel shelters for people experiencing homelessness.
Brothers TD, Leaman M, Bonn M, Lewer D, Atkinson J, Fraser J, Gillis A, Gniewek M, Hawker L, Hayman H, Jorna P, Martell D, O'Donnell T, Rivers-Bowerman H, Genge L. Brothers TD, et al. Drug Alcohol Depend. 2022 Jun 1;235:109440. doi: 10.1016/j.drugalcdep.2022.109440. Epub 2022 Apr 7. Drug Alcohol Depend. 2022. PMID: 35461084 Free PMC article.
Sixty-two (81%) residents were provided medications, alcohol, or cigarettes. Seventeen residents (22%) received opioid agonist treatment (methadone, buprenorphine, or slow-release oral morphine) and 27 (35%) received hydromorphone. ...Six (8%) residents received ben …
Sixty-two (81%) residents were provided medications, alcohol, or cigarettes. Seventeen residents (22%) received opioid agonist treatm …
Drugs in hair. Part I. Metabolisms of major drug classes.
White RM. White RM. Forensic Sci Rev. 2017 Jan;29(1):23-55. Forensic Sci Rev. 2017. PMID: 28119266 Review.
The development of hair as a test matrix and the incorporation of xenobiotics, in general, into the hair matrix were discussed. What constitutes an appropriate metabolite for drug testing to mirror the use of a parent drug was proposed and discussed. The use of meta …
The development of hair as a test matrix and the incorporation of xenobiotics, in general, into the hair matrix were discussed. What constit …
Prescription opioid misuse: characteristics of earliest and most recent memory of hydromorphone use.
Fulton HG, Barrett SP, Stewart SH, Macisaac C. Fulton HG, et al. J Addict Med. 2012 Jun;6(2):137-44. doi: 10.1097/ADM.0b013e3182351550. J Addict Med. 2012. PMID: 22105062
METHODS: Seventy-eight clients enrolled in low-threshold methadone maintenance treatment were interviewed regarding their earliest and most recent uses of hydromorphone. RESULTS: Hydromorphone was first used after trying many different substances (eg, tobacco, al …
METHODS: Seventy-eight clients enrolled in low-threshold methadone maintenance treatment were interviewed regarding their earliest and most …
Effect of Buprenorphine Weekly Depot (CAM2038) and Hydromorphone Blockade in Individuals With Opioid Use Disorder: A Randomized Clinical Trial.
Walsh SL, Comer SD, Lofwall MR, Vince B, Levy-Cooperman N, Kelsh D, Coe MA, Jones JD, Nuzzo PA, Tiberg F, Sheldon B, Kim S. Walsh SL, et al. JAMA Psychiatry. 2017 Sep 1;74(9):894-902. doi: 10.1001/jamapsychiatry.2017.1874. JAMA Psychiatry. 2017. PMID: 28655025 Free PMC article. Clinical Trial.
INTERVENTIONS: A total of five 3-day test sessions evaluated the response to hydromorphone (0, 6, and 18 mg intramuscular in random order; 1 dose/session/day). ...MAIN OUTCOMES AND MEASURES: The primary end point was maximum rating on the visual analog scale for drug …
INTERVENTIONS: A total of five 3-day test sessions evaluated the response to hydromorphone (0, 6, and 18 mg intramuscular in random o …
The relative abuse liability of oral oxycodone, hydrocodone and hydromorphone assessed in prescription opioid abusers.
Walsh SL, Nuzzo PA, Lofwall MR, Holtman JR Jr. Walsh SL, et al. Drug Alcohol Depend. 2008 Dec 1;98(3):191-202. doi: 10.1016/j.drugalcdep.2008.05.007. Epub 2008 Jul 7. Drug Alcohol Depend. 2008. PMID: 18606504 Free PMC article. Clinical Trial.
Abuse of prescription opioids has risen precipitously in the United States. Few controlled comparisons of the abuse liability of the most commonly abused opioids have been conducted. ...
Abuse of prescription opioids has risen precipitously in the United States. Few controlled comparisons of the abuse liability …
74 results