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1999 3
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Page 1
Conflict of Interest Disclosures.
[No authors listed] [No authors listed] Global Spine J. 2023 May;13(2_suppl):568S-591S. doi: 10.1177/21925682231173597. Global Spine J. 2023. PMID: 37222100 Free PMC article. No abstract available.
Non-Typeable Haemophilus influenzae Infection of the Junbo Mouse.
Cheeseman MT, Hood DW. Cheeseman MT, et al. Curr Protoc Mouse Biol. 2017 Mar 2;7(1):29-46. doi: 10.1002/cpmo.24. Curr Protoc Mouse Biol. 2017. PMID: 28252201
An innate immune response is detected in the bulla of Junbo mice following NTHi infection, and bacteria are maintained in some ears at least up to day 56 post-inoculation. The Junbo/NTHi infection model facilitates studies on bacterial pathogenesis and antimicrobial …
An innate immune response is detected in the bulla of Junbo mice following NTHi infection, and bacteria are maintained in some ears a …
Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.
Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N, Maggioni AP, Marso SP, Öhman P, Pagidipati NJ, Poulter N, Ramachandran A, Zinman B, Hernandez AF; EXSCEL Study Group. Holman RR, et al. N Engl J Med. 2017 Sep 28;377(13):1228-1239. doi: 10.1056/NEJMoa1612917. Epub 2017 Sep 14. N Engl J Med. 2017. PMID: 28910237 Free PMC article. Clinical Trial.
Myringotomy in the Junbo mouse model of chronic otitis media alleviates inflammation and cellular hypoxia.
Bhutta MF, Cheeseman MT, Brown SD. Bhutta MF, et al. Laryngoscope. 2014 Sep;124(9):E377-83. doi: 10.1002/lary.24698. Epub 2014 May 30. Laryngoscope. 2014. PMID: 24706577 Free article.
The reason for this is not understood, but there is little to suggest alteration in eustachian tube ventilatory capacity. Previous work has shown that the Junbo mouse model of chronic otitis media has hypoxic middle ear mucosa and bulla fluid leucocytes. ...We performed un …
The reason for this is not understood, but there is little to suggest alteration in eustachian tube ventilatory capacity. Previous work has …
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD. Cheeseman MT, et al. PLoS Genet. 2011 Oct;7(10):e1002336. doi: 10.1371/journal.pgen.1002336. Epub 2011 Oct 20. PLoS Genet. 2011. PMID: 22028672 Free PMC article.
We found that Jeff and Junbo mice labeled in vivo with pimonidazole showed cellular hypoxia in inflammatory cells in the bulla lumen, and in Junbo the middle ear mucosa was also hypoxic. The bulla fluid inflammatory cell numbers were greater and the upregulation of …
We found that Jeff and Junbo mice labeled in vivo with pimonidazole showed cellular hypoxia in inflammatory cells in the bulla lumen, …
Cellular Immune Response against Nontypeable Haemophilus influenzae Infecting the Preinflamed Middle Ear of the Junbo Mouse.
Vikhe PP, Purnell T, Brown SDM, Hood DW. Vikhe PP, et al. Infect Immun. 2019 Nov 18;87(12):e00689-19. doi: 10.1128/IAI.00689-19. Print 2019 Dec. Infect Immun. 2019. PMID: 31548315 Free PMC article.
The pathology of AOM increases during long-term infection in the middle ear (ME), but the host cellular immune response to bacterial infection in this inflamed environment is poorly understood. Using the Junbo mouse, a characterized NTHi infection model, we analyzed the ce …
The pathology of AOM increases during long-term infection in the middle ear (ME), but the host cellular immune response to bacterial infecti …
Cellular content plays a crucial role in Non-typeable Haemophilus influenzae infection of preinflamed Junbo mouse middle ear.
Vikhe PP, Purnell T, Brown SDM, Hood DW. Vikhe PP, et al. Cell Microbiol. 2019 Jan;21(1):e12960. doi: 10.1111/cmi.12960. Epub 2018 Oct 15. Cell Microbiol. 2019. PMID: 30265765 Free PMC article.
The MEF of the Junbo mouse was heterogeneous between ears and was graded from 1 to 5; 1 being highly serous/clear and 5 being heavily viscous/opaque. ...These data underline a role for immune cells, specifically monocytes and neutrophils, and cell necrosis in NTHi infectio …
The MEF of the Junbo mouse was heterogeneous between ears and was graded from 1 to 5; 1 being highly serous/clear and 5 being heavily …
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media.
Parkinson N, Hardisty-Hughes RE, Tateossian H, Tsai HT, Brooker D, Morse S, Lalane Z, MacKenzie F, Fray M, Glenister P, Woodward AM, Polley S, Barbaric I, Dear N, Hough TA, Hunter AJ, Cheeseman MT, Brown SD. Parkinson N, et al. PLoS Genet. 2006 Oct 6;2(10):e149. doi: 10.1371/journal.pgen.0020149. PLoS Genet. 2006. PMID: 17029558 Free PMC article.
We identified an N-ethyl-N-nitrosourea-induced dominant mouse mutant Junbo with hearing loss due to chronic suppurative OM and otorrhea. ...This protein is expressed in middle ear basal epithelial cells, fibroblasts, and neutrophil leukocytes at postnatal day 13 and 21 whe …
We identified an N-ethyl-N-nitrosourea-induced dominant mouse mutant Junbo with hearing loss due to chronic suppurative OM and otorrh …
140 results