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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 8
1982 2
1983 2
1984 2
1985 2
1986 2
1987 1
1988 5
1989 5
1990 10
1991 6
1992 5
1993 11
1994 8
1995 10
1996 10
1997 15
1998 15
1999 23
2000 24
2001 16
2002 27
2003 43
2004 47
2005 46
2006 78
2007 72
2008 93
2009 110
2010 141
2011 156
2012 182
2013 205
2014 231
2015 243
2016 263
2017 246
2018 298
2019 341
2020 383
2021 421
2022 509
2023 637
2024 479

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4,881 results

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Page 1
Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer.
Niu N, Shen X, Wang Z, Chen Y, Weng Y, Yu F, Tang Y, Lu P, Liu M, Wang L, Sun Y, Yang M, Shen B, Jin J, Lu Z, Jiang K, Shi Y, Xue J. Niu N, et al. Cancer Cell. 2024 May 13;42(5):869-884.e9. doi: 10.1016/j.ccell.2024.03.005. Epub 2024 Apr 4. Cancer Cell. 2024. PMID: 38579725
Lipid-laden CAFs then enhance tumor progression by providing lipids for mitochondrial oxidative phosphorylation via ABCA8a transporter. Together, our study links CAF heterogeneity to epigenetic dysregulation in tumor cells, highlighting a previously unappreciated metabolic …
Lipid-laden CAFs then enhance tumor progression by providing lipids for mitochondrial oxidative phosphorylation via ABCA8a transporter. Toge …
Regulation of Stem Cell Aging by Metabolism and Epigenetics.
Ren R, Ocampo A, Liu GH, Izpisua Belmonte JC. Ren R, et al. Cell Metab. 2017 Sep 5;26(3):460-474. doi: 10.1016/j.cmet.2017.07.019. Epub 2017 Aug 17. Cell Metab. 2017. PMID: 28826795 Free article. Review.
This review focuses on current knowledge regarding the mechanisms of stem cell aging, and the links between cellular metabolism and epigenetic regulation. In addition, we discuss how these interactions sense and respond to environmental stress in order to maintain stem cel …
This review focuses on current knowledge regarding the mechanisms of stem cell aging, and the links between cellular metabolism and e …
Agrochemicals and obesity.
Ren XM, Kuo Y, Blumberg B. Ren XM, et al. Mol Cell Endocrinol. 2020 Sep 15;515:110926. doi: 10.1016/j.mce.2020.110926. Epub 2020 Jun 30. Mol Cell Endocrinol. 2020. PMID: 32619583 Free PMC article. Review.
Agrochemicals are a class of chemicals extensively used in agriculture, which have been widely detected in human. There is now considerable evidence linking human exposure to agrochemicals with obesity. This review summarizes human epidemiological evidence and experimental …
Agrochemicals are a class of chemicals extensively used in agriculture, which have been widely detected in human. There is now considerable …
Injectable, self-healing hydrogel adhesives with firm tissue adhesion and on-demand biodegradation for sutureless wound closure.
Ren H, Zhang Z, Cheng X, Zou Z, Chen X, He C. Ren H, et al. Sci Adv. 2023 Aug 18;9(33):eadh4327. doi: 10.1126/sciadv.adh4327. Epub 2023 Aug 16. Sci Adv. 2023. PMID: 37585520 Free PMC article.
Here, injectable and biocompatible hydrogel adhesives are developed via catalyst-free o-phthalaldehyde/amine (hydrazide) cross-linking reaction. The hydrogels demonstrate rapid and firm adhesion to various tissues, and an o-phthalaldehyde-mediated tissue adhesion mechanism …
Here, injectable and biocompatible hydrogel adhesives are developed via catalyst-free o-phthalaldehyde/amine (hydrazide) cross-linking …
Cross-Linking and Charging Molecular Magnetoelectronics.
Huang Y, Chen Y, Hu Y, Mitchell T, An L, Li Z, Benedict J, Li H, Ren S. Huang Y, et al. Nano Lett. 2021 May 12;21(9):4099-4105. doi: 10.1021/acs.nanolett.1c01146. Epub 2021 Apr 22. Nano Lett. 2021. PMID: 33886320
Here, we report a promising design strategy to shift the paradigm of next-generation molecular magnetoelectrics, which relies on the integration between molecular magnetism and electric conductivity though an in situ cross-linking strategy. Following this approach, we demo …
Here, we report a promising design strategy to shift the paradigm of next-generation molecular magnetoelectrics, which relies on the integra …
Detecting and interpreting DNA methylation marks.
Ren R, Horton JR, Zhang X, Blumenthal RM, Cheng X. Ren R, et al. Curr Opin Struct Biol. 2018 Dec;53:88-99. doi: 10.1016/j.sbi.2018.06.004. Epub 2018 Jul 19. Curr Opin Struct Biol. 2018. PMID: 30031306 Free PMC article. Review.
This review focuses on recent developments in characterizing the functional and structural links between the modification status of two DNA bases: 5-methylcytosine and 5-methyluracil (thymine)....
This review focuses on recent developments in characterizing the functional and structural links between the modification status of t …
RIPK3-MLKL necroptotic signalling amplifies STING pathway and exacerbates lethal sepsis.
Zhang X, Wu J, Liu Q, Li X, Yang Y, Wu L, Wu X, Zhao Y, Ren J. Zhang X, et al. Clin Transl Med. 2023 Jul;13(7):e1334. doi: 10.1002/ctm2.1334. Clin Transl Med. 2023. PMID: 37475188 Free PMC article.
Targeting necroptotic signaling ameliorates STING activation during DMXAA-induced intestinal injury and sepsis. CONCLUSIONS: These findings elucidate molecular mechanisms linking necroptosis to the STING pathway, and suggest a potential benefit of therapeutic targeting of …
Targeting necroptotic signaling ameliorates STING activation during DMXAA-induced intestinal injury and sepsis. CONCLUSIONS: These findings …
(S,Z)-1-Chloro-3-[(3,4,5-trimeth-oxy-benzyl-idene)amino]-propan-2-ol.
Ren Y, Qian S, Hai L, Fan W, Wu Y. Ren Y, et al. Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 8;67(Pt 2):o245. doi: 10.1107/S1600536810053420. Acta Crystallogr Sect E Struct Rep Online. 2011. PMID: 21522939 Free PMC article.
In the title compound, C(13)H(18)ClNO(4), the two meth-oxy groups at the meta positions of the attached benzene ring are close to being coplanar with the ring [the meth-oxy C atoms deviate by 0.267 (7) and 0.059 (7) A], whereas the third meth-oxy group at the para position is not …
In the title compound, C(13)H(18)ClNO(4), the two meth-oxy groups at the meta positions of the attached benzene ring are close to being copl …
Antibody-Targeted TNFRSF Activation for Cancer Immunotherapy: The Role of FcgammaRIIB Cross-Linking.
Liu L, Wu Y, Ye K, Cai M, Zhuang G, Wang J. Liu L, et al. Front Pharmacol. 2022 Jul 5;13:924197. doi: 10.3389/fphar.2022.924197. eCollection 2022. Front Pharmacol. 2022. PMID: 35865955 Free PMC article. Review.
Leveraging the interactions between antibodies and the inhibitory Fc receptor FcgammaRIIB to optimize co-stimulation agonistic activities dependent on FcgammaRIIB cross-linking selectively in tumor microenvironment represents the current frontier, which also includes cross …
Leveraging the interactions between antibodies and the inhibitory Fc receptor FcgammaRIIB to optimize co-stimulation agonistic activities de …
Towards an integrated understanding of dietary phenotypes.
Raubenheimer D, Hou R, Dong Y, Ren C, Cui Z. Raubenheimer D, et al. Philos Trans R Soc Lond B Biol Sci. 2023 Dec 4;378(1891):20220545. doi: 10.1098/rstb.2022.0545. Epub 2023 Oct 16. Philos Trans R Soc Lond B Biol Sci. 2023. PMID: 37839453 Review.
With accumulating information on the many facets of this association arises a need for systems-based approaches that integrate dietary components and their links with ecology, feeding, post-ingestive processes and the functional and ecological consequences of these interac …
With accumulating information on the many facets of this association arises a need for systems-based approaches that integrate dietary compo …
4,881 results