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Effect of water deprivation for 48 hours on the pharmacokinetics and pharmacodynamics of azosemide in rats.
Ha HA, Lee SH, Kim SH, Kim ON, Lee MG. Ha HA, et al. Among authors: kim on. Res Commun Mol Pathol Pharmacol. 1996 Jul;93(1):109-28. Res Commun Mol Pathol Pharmacol. 1996. PMID: 8865375
After oral administration of azosemide, the values of AeAZ0 (591 vs 318 micrograms) and CLR (2.22 vs 0.875 mL/min/kg) decreased significantly in the water-deprived rats. The 12-h urine output per g kidney was also reduced significantly in the water-deprived rats after both …
After oral administration of azosemide, the values of AeAZ0 (591 vs 318 micrograms) and CLR (2.22 vs 0.875 mL/min/kg) decreased signi …
Effects of water deprivation on the pharmacokinetics and pharmacodynamics of bumetanide in rats.
Huang JY, Kim ON, Lee SH, Lee MG. Huang JY, et al. Among authors: kim on. Biopharm Drug Dispos. 1993 Aug;14(6):463-74. doi: 10.1002/bdd.2510140602. Biopharm Drug Dispos. 1993. PMID: 8218964
The kidney function based on CLIot (9.87 vs 2.14 ml min-1 kg-1) reduced significantly in water deprived rats. The 8-h urinary excretions of sodium (0.430 vs 0.0818 mmol), potassium (0.567 vs 0.270 mmol), and chloride (0.549 vs 0.0624 mmol) per 100 g body weight also reduce …
The kidney function based on CLIot (9.87 vs 2.14 ml min-1 kg-1) reduced significantly in water deprived rats. The 8-h urinary excreti …