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Page 1
In vitro susceptibility of chromoblastomycosis agents to antifungal drugs: A systematic review.
da Silva Hellwig AH, Heidrich D, Zanette RA, Scroferneker ML. da Silva Hellwig AH, et al. J Glob Antimicrob Resist. 2019 Mar;16:108-114. doi: 10.1016/j.jgar.2018.09.010. Epub 2018 Sep 25. J Glob Antimicrob Resist. 2019. PMID: 30266638
However, cure rates vary from 15% to 80% when these drugs are used as monotherapy. A systematic review of the in vitro susceptibility of CBM agents to antifungal drugs, alone and in combination, was conducted using the Cochrane methodology. ...Based on minimum inhibitory c …
However, cure rates vary from 15% to 80% when these drugs are used as monotherapy. A systematic review of the in vitro susceptibility …
Melanin and chromoblastomycosis agents: Characterization, functions, and relation with antifungals.
Koehler A, Heidrich D, Pagani DM, Corbellini VA, Scroferneker ML. Koehler A, et al. J Basic Microbiol. 2021 Mar;61(3):203-211. doi: 10.1002/jobm.202000664. Epub 2021 Feb 12. J Basic Microbiol. 2021. PMID: 33576034 Review.
It is synthesized in a pathway known as the pentaketide pathway, which has the agrochemical tricyclazole as an inhibitor, widely used in in vitro studies because it does not prevent the growth of fungi. There are different methodologies for qualitative and quantitative ana …
It is synthesized in a pathway known as the pentaketide pathway, which has the agrochemical tricyclazole as an inhibitor, widely used in in …
In vitro susceptibility of chromoblastomycosis agents to five antifungal drugs and to the combination of terbinafine and amphotericin B.
Daboit TC, Massotti Magagnin C, Heidrich D, Czekster Antochevis L, Vigolo S, Collares Meirelles L, Alves K, Scroferneker ML. Daboit TC, et al. Mycoses. 2014 Feb;57(2):116-20. doi: 10.1111/myc.12111. Epub 2013 Jul 29. Mycoses. 2014. PMID: 23895037
In this sense, antifungal activity tests in vitro could be useful. However, trials with chromoblastomycosis agents are scarce. The aim of this study was to evaluate both the in vitro susceptibility of 60 chromoblastomycosis agents to five antifungals and the combina …
In this sense, antifungal activity tests in vitro could be useful. However, trials with chromoblastomycosis agents are scarce. The ai …
Antifungal activity of azoles, allylamines, and 8-hidroxiquinolines, alone and in combination, against Malassezia pachydermatis in vitro and in vivo.
Merkel S, Pippi B, Reginatto P, Joaquim AR, Machado GRM, Heidrich D, Furasté ME, Silva JA, Konzen EJS, Scroferneker ML, Andrade SF, Fuentefria AM, Zanette RA. Merkel S, et al. J Mycol Med. 2024 Jun;34(2):101475. doi: 10.1016/j.mycmed.2024.101475. Epub 2024 Mar 11. J Mycol Med. 2024. PMID: 38479291
Susceptibility to the drugs was evaluated by in vitro broth microdilution and time-kill assays. The Toll-deficient Drosophila melanogaster fly model was used to assess the efficacy of drugs in vivo. In vitro tests showed that ketoconazole (KTZ) was the most active d …
Susceptibility to the drugs was evaluated by in vitro broth microdilution and time-kill assays. The Toll-deficient Drosophila melanog …
Hexokinase 2 from Saccharomyces cerevisiae: regulation of oligomeric structure by in vivo phosphorylation at serine-14.
Behlke J, Heidrich K, Naumann M, Müller EC, Otto A, Reuter R, Kriegel T. Behlke J, et al. Biochemistry. 1998 Aug 25;37(34):11989-95. doi: 10.1021/bi980914m. Biochemistry. 1998. PMID: 9718324
Homodimeric hexokinase 2 from Saccharomyces cerevisiae is known to have two sites of phosphorylation: for serine-14 the modification in vivo increases with glucose exhaustion [Kriegel et al. (1994) Biochemistry 33, 148-152], while for serine-157 it occurs in vitro with ATP …
Homodimeric hexokinase 2 from Saccharomyces cerevisiae is known to have two sites of phosphorylation: for serine-14 the modification in vivo …
Chromoblastomycosis caused by Rhinocladiella similis: Case report.
Heidrich D, González GM, Pagani DM, Ramírez-Castrillón M, Scroferneker ML. Heidrich D, et al. Med Mycol Case Rep. 2017 Apr 7;16:25-27. doi: 10.1016/j.mmcr.2017.04.002. eCollection 2017 Jun. Med Mycol Case Rep. 2017. PMID: 28458993 Free PMC article.
The pathogenic fungal species was identified as Rhinocladiella similis by ITS region sequencing. In vitro analyses indicate that the fungus was sensitive to posaconazole and itraconazole. ...
The pathogenic fungal species was identified as Rhinocladiella similis by ITS region sequencing. In vitro analyses indicate that the …
Magnesium degradation influenced by buffering salts in concentrations typical of in vitro and in vivo models.
Agha NA, Feyerabend F, Mihailova B, Heidrich S, Bismayer U, Willumeit-Römer R. Agha NA, et al. Mater Sci Eng C Mater Biol Appl. 2016 Jan 1;58:817-25. doi: 10.1016/j.msec.2015.09.067. Epub 2015 Sep 18. Mater Sci Eng C Mater Biol Appl. 2016. PMID: 26478376
Moreover, too fast or uncontrolled degradation is detrimental for the outcome in vivo. Therefore in vitro setups utilizing physiological conditions are promising for the material/degradation analysis prior to animal experiments. ...Additionally, different inorganic salts w …
Moreover, too fast or uncontrolled degradation is detrimental for the outcome in vivo. Therefore in vitro setups utilizing physiologi …
Blood compatibility of magnesium and its alloys.
Feyerabend F, Wendel HP, Mihailova B, Heidrich S, Agha NA, Bismayer U, Willumeit-Römer R. Feyerabend F, et al. Acta Biomater. 2015 Oct;25:384-94. doi: 10.1016/j.actbio.2015.07.029. Epub 2015 Jul 22. Acta Biomater. 2015. PMID: 26210283
CONCLUSIONS: The active regulation of corrosion mechanisms of magnesium alloys by different cell types should be more in the focus of research to bridge the gap between in vitro and in vivo observations and to understand the mechanism of action. This in turn could lead to …
CONCLUSIONS: The active regulation of corrosion mechanisms of magnesium alloys by different cell types should be more in the focus of resear …
Sporotrichosis by Sporothrix schenckii senso stricto with itraconazole resistance and terbinafine sensitivity observed in vitro and in vivo: Case report.
Vettorato R, Heidrich D, Fraga F, Ribeiro AC, Pagani DM, Timotheo C, Amaro TG, Vettorato G, Scroferneker ML. Vettorato R, et al. Med Mycol Case Rep. 2017 Oct 28;19:18-20. doi: 10.1016/j.mmcr.2017.10.001. eCollection 2018 Mar. Med Mycol Case Rep. 2017. PMID: 29204336 Free PMC article.
The initial treatment was itraconazole (200 mg/day), but in vitro antifungal susceptibility demonstrated high resistant to this and another six antifungals, with exception to terbinafine. ...
The initial treatment was itraconazole (200 mg/day), but in vitro antifungal susceptibility demonstrated high resistant to this and a …
82 results