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Page 1
Trimeric Architecture Ensures the Stability and Biological Activity of the Calf Purine Nucleoside Phosphorylase: In Silico and In Vitro Studies of Monomeric and Trimeric Forms of the Enzyme.
Int J Mol Sci. 2023 Jan 21;24(3):2157. doi: 10.3390/ijms24032157.
Int J Mol Sci. 2023.
PMID: 36768477
Free PMC article.
Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state.
Wielgus-Kutrowska B, Breer K, Hashimoto M, Hikishima S, Yokomatsu T, Narczyk M, Dyzma A, Girstun A, Staroń K, Bzowska A.
Wielgus-Kutrowska B, et al. Among authors: dyzma a.
Bioorg Med Chem. 2012 Nov 15;20(22):6758-69. doi: 10.1016/j.bmc.2012.08.045. Epub 2012 Sep 17.
Bioorg Med Chem. 2012.
PMID: 23040896
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Purine nucleoside phosphorylase activity decline is linked to the decay of the trimeric form of the enzyme.
Wielgus-Kutrowska B, Modrak-Wójcik A, Dyzma A, Breer K, Zolkiewski M, Bzowska A.
Wielgus-Kutrowska B, et al. Among authors: dyzma a.
Arch Biochem Biophys. 2014 May 1;549:40-8. doi: 10.1016/j.abb.2014.03.009. Epub 2014 Mar 28.
Arch Biochem Biophys. 2014.
PMID: 24686197
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