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Screening for drugs to reduce zebrafish aggression identifies caffeine and sildenafil.
Gutiérrez HC, Vacca I, Schoenmacker G, Cleal M, Tochwin A, O'Connor B, Young AMJ, Vasquez AA, Winter MJ, Parker MO, Norton WHJ. Gutiérrez HC, et al. Among authors: tochwin a. Eur Neuropsychopharmacol. 2020 Jan;30:17-29. doi: 10.1016/j.euroneuro.2019.10.005. Epub 2019 Nov 1. Eur Neuropsychopharmacol. 2020. PMID: 31679888 Free article.
A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation.
Winter MJ, Ono Y, Ball JS, Walentinsson A, Michaelsson E, Tochwin A, Scholpp S, Tyler CR, Rees S, Hetheridge MJ, Bohlooly-Y M. Winter MJ, et al. Among authors: tochwin a. Front Pharmacol. 2022 Apr 25;13:827686. doi: 10.3389/fphar.2022.827686. eCollection 2022. Front Pharmacol. 2022. PMID: 35548346 Free PMC article.
Functional brain imaging in larval zebrafish for characterising the effects of seizurogenic compounds acting via a range of pharmacological mechanisms.
Winter MJ, Pinion J, Tochwin A, Takesono A, Ball JS, Grabowski P, Metz J, Trznadel M, Tse K, Redfern WS, Hetheridge MJ, Goodfellow M, Randall AD, Tyler CR. Winter MJ, et al. Among authors: tochwin a. Br J Pharmacol. 2021 Jul;178(13):2671-2689. doi: 10.1111/bph.15458. Epub 2021 May 5. Br J Pharmacol. 2021. PMID: 33768524 Free article.
From mRNA Expression of Drug Disposition Genes to In Vivo Assessment of CYP-Mediated Biotransformation during Zebrafish Embryonic and Larval Development.
Verbueken E, Bars C, Ball JS, Periz-Stanacev J, Marei WFA, Tochwin A, Gabriëls IJ, Michiels EDG, Stinckens E, Vergauwen L, Knapen D, Van Ginneken CJ, Van Cruchten SJ. Verbueken E, et al. Among authors: tochwin a. Int J Mol Sci. 2018 Dec 10;19(12):3976. doi: 10.3390/ijms19123976. Int J Mol Sci. 2018. PMID: 30544719 Free PMC article.