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2016 1
2017 2
2018 11
2019 6
2020 2
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Page 1
MF-8, a novel promising arylpiperazine-hydantoin based 5-HT7 receptor antagonist: In vitro drug-likeness studies and in vivo pharmacological evaluation.
Latacz G, Lubelska A, Jastrzębska-Więsek M, Partyka A, Kucwaj-Brysz K, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Latacz G, et al. Among authors: Lubelska A. Bioorg Med Chem Lett. 2018 Mar 1;28(5):878-883. doi: 10.1016/j.bmcl.2018.02.003. Epub 2018 Feb 3. Bioorg Med Chem Lett. 2018. PMID: 29439902
Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H3 receptor ligands.
Łażewska D, Kaleta M, Schwed JS, Karcz T, Mogilski S, Latacz G, Olejarz A, Siwek A, Kubacka M, Lubelska A, Honkisz E, Handzlik J, Filipek B, Stark H, Kieć-Kononowicz K. Łażewska D, et al. Among authors: Lubelska A. Bioorg Med Chem. 2017 Oct 15;25(20):5341-5354. doi: 10.1016/j.bmc.2017.07.058. Epub 2017 Jul 29. Bioorg Med Chem. 2017. PMID: 28797771
Novel naphthyloxy derivatives - Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation.
Łażewska D, Kaleta M, Hagenow S, Mogilski S, Latacz G, Karcz T, Lubelska A, Honkisz E, Handzlik J, Reiner D, Satała G, Filipek B, Stark H, Kieć-Kononowicz K. Łażewska D, et al. Among authors: Lubelska A. Bioorg Med Chem. 2018 May 15;26(9):2573-2585. doi: 10.1016/j.bmc.2018.04.023. Epub 2018 Apr 11. Bioorg Med Chem. 2018. PMID: 29681486
Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation.
Kucwaj-Brysz K, Warszycki D, Podlewska S, Witek J, Witek K, González Izquierdo A, Satała G, Loza MI, Lubelska A, Latacz G, Bojarski AJ, Castro M, Kieć-Kononowicz K, Handzlik J. Kucwaj-Brysz K, et al. Among authors: Lubelska A. Eur J Med Chem. 2016 Apr 13;112:258-269. doi: 10.1016/j.ejmech.2016.02.024. Epub 2016 Feb 9. Eur J Med Chem. 2016. PMID: 26900658
In the search for a lead structure among series of potent and selective hydantoin 5-HT7 R agents: The drug-likeness in vitro study.
Latacz G, Lubelska A, Jastrzębska-Więsek M, Partyka A, Sobiło A, Olejarz A, Kucwaj-Brysz K, Satała G, Bojarski AJ, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Latacz G, et al. Among authors: Lubelska A. Chem Biol Drug Des. 2017 Dec;90(6):1295-1306. doi: 10.1111/cbdd.13106. Epub 2017 Oct 3. Chem Biol Drug Des. 2017. PMID: 28886235
Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats.
Alachkar A, Łażewska D, Latacz G, Frank A, Siwek A, Lubelska A, Honkisz-Orzechowska E, Handzlik J, Stark H, Kieć-Kononowicz K, Sadek B. Alachkar A, et al. Among authors: Lubelska A. Int J Mol Sci. 2018 Oct 29;19(11):3386. doi: 10.3390/ijms19113386. Int J Mol Sci. 2018. PMID: 30380674 Free PMC article.
The role of aryl-topology in balancing between selective and dual 5-HT7R/5-HT1A actions of 3,5-substituted hydantoins.
Kucwaj-Brysz K, Kurczab R, Żesławska E, Lubelska A, Marć MA, Latacz G, Satała G, Nitek W, Kieć-Kononowicz K, Handzlik J. Kucwaj-Brysz K, et al. Among authors: Lubelska A. Medchemcomm. 2018 May 8;9(6):1033-1044. doi: 10.1039/c8md00168e. eCollection 2018 Jun 1. Medchemcomm. 2018. PMID: 30108992 Free PMC article.
Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT₆ Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo.
Kurczab R, Ali W, Łażewska D, Kotańska M, Jastrzębska-Więsek M, Satała G, Więcek M, Lubelska A, Latacz G, Partyka A, Starek M, Dąbrowska M, Wesołowska A, Jacob C, Kieć-Kononowicz K, Handzlik J. Kurczab R, et al. Among authors: Lubelska A. Molecules. 2018 Oct 3;23(10):2529. doi: 10.3390/molecules23102529. Molecules. 2018. PMID: 30282913 Free PMC article.
Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands.
Szczepańska K, Karcz T, Mogilski S, Siwek A, Kuder KJ, Latacz G, Kubacka M, Hagenow S, Lubelska A, Olejarz A, Kotańska M, Sadek B, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: Lubelska A. Eur J Med Chem. 2018 May 25;152:223-234. doi: 10.1016/j.ejmech.2018.04.043. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29723785
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction.
Felicetti T, Cannalire R, Pietrella D, Latacz G, Lubelska A, Manfroni G, Barreca ML, Massari S, Tabarrini O, Kieć-Kononowicz K, Schindler BD, Kaatz GW, Cecchetti V, Sabatini S. Felicetti T, et al. Among authors: Lubelska A. J Med Chem. 2018 Sep 13;61(17):7827-7848. doi: 10.1021/acs.jmedchem.8b00791. Epub 2018 Aug 17. J Med Chem. 2018. PMID: 30067360
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